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临床前CDMO研发化合物筛选
Rifapentine
中文名称:利福喷丁
CAS号:61379-65-5
分子式: C47H64N4O12 分子量: 877.03
产品形式: free base
研发状态: Not yet recruiting
研发用途: Pediatric HIV Infection; Latent Tuberculosis
研究机构: Brigham and Women''s Hospital; APIN Public Health Initiatives; University of Cape Town
研发日期: May-24
研发阶段: Phase 1
Rifapentine (MDL473) is an antibiotic, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.
5'-Adenylic acid
中文名称:腺苷酸
CAS号:61-19-8
分子式: C10H14N5O7P 分子量: 347.22
产品形式: free base
研发状态: Not yet recruiting
研发用途: Child Sexual Abuse
研究机构: University of Minnesota
研发日期: June 15 2024
研发阶段: Not Applicable
AMP, also known as 5'-Adenylic acid and Adenosine monophosphate, is a nucleotide that is found in RNA. It is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.
Quinine HCl Dihydrate
中文名称:奎宁盐酸盐二水合物
CAS号:6119-47-7
分子式: C20H24N2O2.HCl.2H2O 分子量: 396.91
产品形式: Hydrochloride dihydrate
研发状态: Unknown status
研发用途: Obesity
研究机构: Universitaire Ziekenhuizen KU Leuven
研发日期: October 29 2020
研发阶段: Phase 1
Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.
Glycerol phenylbutyrate
中文名称: 苯丁酸甘油酯
CAS号:611168-24-2
分子式: C33H38O6 分子量: 530.65
产品形式: Free Base
研发状态: Recruiting
研发用途: Corticobasal Syndrome (CBS)
研究机构: Technical University of Munich
研发日期: December 12 2023
研发阶段: Phase 2
Glycerol phenylbutyrate (GT4P, HPN-100M, Ravicti) is a nitrogen-binding agent and acts as a sigma-2 (σ2) receptor ligand with a pKi of 8.02. Glycerol phenylbutyrate is a prodrug in which phenylbutyrate (PBA) is released from the glycerol backbone by lipases in the gastrointestinal tract.
Icotinib (BPI-2009H)
中文名称:埃克替尼
CAS号:610798-31-7
分子式: C22H21N3O4 分子量: 391.42
产品形式: free base
研发状态: Unknown status
研发用途: Non-small Cell Lung Cancer
研究机构: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
研发日期: Jun-16
研发阶段: Phase 3
Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
Teicoplanin
中文名称:替考拉宁
CAS号:61036-62-2
分子式: C77H77N9O31Cl2.R 分子量: 1709.39
产品形式: free base
研发状态: Completed
研发用途: Kidney Failure Chronic; Antibiotics; Hemodialysis
研究机构: University Hospital Ghent; University Ghent
研发日期: September 15 2016
研发阶段: --
Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
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