Meet the molecules of the year 2026 满足2026年的分子

C&EN editors' annual roundup of some of the most interesting molecules we’ve covered this year （C&EN编辑者们每年对今年我们所报道的一些最有趣的分子进行综述）
📰来源: C&EN
📆 日期: 2026-10-26
🔗来源: https://cen.acs.org/synthesis/molecules-of-year-2026/104/web/2026/10

Chemists make 3D molecules from flat precursors 化学家用平地先质制造出三维分子

Single carbon insertion forges complex spirocycles in one step （单碳插入在一步内形成复杂的螺旋循环）
📰来源: C&EN
📆 日期: 2026-10-20
🔗来源: https://cen.acs.org/synthesis/spirocycle-carbon-insertion-3D/104/web/2026/10

Mousanes scurry into the medicinal chemist’s toolbox Moussanes冲入药用化学家的工具箱

Serially spiro-fused cyclobutanes could be a new motif for drugmakers （连续喷出环丁烷可能是毒品制造者的新动机）
📰来源: C&EN
📆 日期: 2026-10-16
🔗来源: https://cen.acs.org/synthesis/medicinal-chemistry/mousanes-scurry-medicinal-chemists-toolbox/104/web/2026/10

Aralez Bio creates noncanonical amino acids 阿列兹 生物生成非氨基酸

The start-up uses Nobel Prize–winning science to expand drugmakers’ options in making peptide drugs （创业者利用诺贝尔奖获奖科学来扩大毒品制造者制造活泼药物的选择）
📰来源: C&EN
📆 日期: 2026-10-12
🔗来源: https://cen.acs.org/synthesis/biocatalysis/aralez-start-up-unnatural-amino-acids/104/web/2026/10

This molecule lives on the brink of self-destruction 这种分子生活在自毁的边缘

Chemists coax strong electrophile to coexist peacefully with nucleophilic groups （化学家同轴强电费 与核细胞组和平共处）
📰来源: C&EN
📆 日期: 2026-05-20
🔗来源: https://cen.acs.org/synthesis/synthesis-oxonium-nucleophile/104/web/2026/05

Copper finally joins the metallocene club 小铜终于加入了冶金会

More than 70 years after ferrocene’s discovery, cuprocene fills a long-standing gap in the sandwich menu （70多年后,铁甲的发现, Cuprocene填补了三明治菜单中长期存在的空白）
📰来源: C&EN
📆 日期: 2026-02-16
🔗来源: https://cen.acs.org/synthesis/cuprocene-copper-sandwich-complex/104/web/2026/02

2 unusual alkenes stretch the limits of molecular geometry 2个不寻常的折叠物会拉长分子几何的极限

The extremely strained structures of cubene and 1,7-quadricyclene could be handy in drug synthesis （立方体和1,7-四氯环乙烷结构极为紧张,在药物合成方面可能十分有用。）
📰来源: C&EN
📆 日期: 2026-01-21
🔗来源: https://cen.acs.org/synthesis/cubene-quadricyclene-distorted-alkene/104/web/2026/01

The first all-carbon ring that’s stable at room temperature 第一个在室温下稳定的全碳环

Researchers thread cyclo[48]carbon into a supramolecular assembly, rendering it stable enough to characterize
📰来源: C&EN
📆 日期: 2025-08-14
🔗来源: https://cen.acs.org/physical-chemistry/chemical-bonding/firstcarbon-ring-s-stable-room/103/web/2025/08

Chimpanzees use the same plants we do to treat similar illnesses 黑猩猩用同样的植物治疗类似的疾病

A new review of recent studies shows the great apes rely on medicinal plants to heal infections, but the plants’ chemistry remains mostly a mystery （对最近研究的新回顾显示 巨猿依靠药用植物来治疗感染 但植物的化学特性 大多仍然是个谜）
📰来源: C&EN
📆 日期: 2025-08-08
🔗来源: https://cen.acs.org/pharmaceuticals/drug-discovery/Chimpanzees-use-same-plants-treat-we-do-to-treat-similar-illnesses/103/web/2025/08

Yogurt-derived hydrogels for regenerative medicine 用于再生医学的酸奶衍生水凝胶

This hydrogel mimics biological tissue, boosting blood vessel formation and immune response （这种水凝胶会模仿生物组织,促进血管形成和免疫反应.）
📰来源: C&EN
📆 日期: 2025-08-08
🔗来源: https://cen.acs.org/biological-chemistry/natural-products/Yogurt-derived-hydrogels-regenerative-medicine/103/web/2025/08

Chemistry in Pictures: Golden film 图片中的化学:金相片

📰来源: C&EN
📆 日期: 2025-08-07
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Golden-film/103/web/2025/08

Chemistry in Pictures: Photocatalysis 图片中的化学:光催化

📰来源: C&EN
📆 日期: 2025-08-06
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Photocatalysis/103/web/2025/08

Chemistry in Pictures: Fluorescent funnel 图片中的化学:荧光漏斗

📰来源: C&EN
📆 日期: 2025-07-25
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Fluorescent-funnel/103/web/2025/07

Moon dust and astronaut breath can keep people alive in space 月球尘埃和宇航员的呼吸可以让人在太空活下来

Scientists have found a way to get oxygen, water, and fuel from lunar dirt （科学家们已经找到方法从月球泥土中取出氧气、水和燃料）
📰来源: C&EN
📆 日期: 2025-07-23
🔗来源: https://cen.acs.org/physical-chemistry/astrochemistry/Moon-dust-astronaut-breath-keep/103/web/2025/07

Watch a new self-driving molecular machine in action 注意新的自动驾驶分子机器

Chemists use a cycle of enzymatic oxidation and chemical reduction to drive molecular rotation （化学家使用酶氧化和化学还原的循环来驱动分子自转）
📰来源: C&EN
📆 日期: 2025-07-18
🔗来源: https://cen.acs.org/materials/molecular-machines/Watch-new-self-driving-molecular/103/web/2025/07

Metal complexes rip open benzene 金属复合物 撕开苯

Scandium and chromium compounds team up to convert iconic molecule into linear product at room temperature （在室温下将相像分子转化为线性产品）
📰来源: C&EN
📆 日期: 2025-07-16
🔗来源: https://cen.acs.org/physical-chemistry/chemical-bonding/Metal-complexes-rip-open-benzene/103/web/2025/07

Chemistry in Pictures: That’s no moon 图片中的化学: 这不是月亮

That’s an organometallic complex （这是一个有机金属综合体）
📰来源: C&EN
📆 日期: 2025-07-14
🔗来源: https://cen.acs.org/synthesis/catalysis/Chemistry-Pictures-s-moon/103/web/2025/07

Greening Chemistry: Time is a terrible reagent to waste 绿化化学:时间是浪费的可怕试剂

Hours spent on chemical reactions can’t be recycled. Let’s make sure we conserve the ultimate nonrenewable resource （用在化学反应上的小时不能被回收。 让我们确保保护最终的不可再生资源）
📰来源: C&EN
📆 日期: 2025-07-14
🔗来源: https://cen.acs.org/synthesis/green-chemistry/Greening-chemistry-Time-terrible-reagent/103/web/2025/07

Atom-swapped morphine may help create safer painkillers 原子刮去的吗啡可能有助于制造更安全的止痛药

By putting a carbon atom in place of a core oxygen, chemists constructed an opioid that blocks pain with less respiratory depression in mice （通过将碳原子取而代之,化学家们制造出一种类阿片,将小鼠呼吸压抑程度较低的疼痛阻断）
📰来源: C&EN
📆 日期: 2025-07-11
🔗来源: https://cen.acs.org/synthesis/medicinal-chemistry/Atom-swapped-morphine-help-create/103/web/2025/07

Skeletal editing: How close are we to true cut-and-paste chemistry? 骨骼编辑:我们离真正的剪贴化学有多近?.

Reactions that alter organic scaffolds by a single atom are already proving useful, but time will tell if they’ll fundamentally change how molecules are made （由单个原子改变有机脚手架的反应已经证明是有用的,）
📰来源: C&EN
📆 日期: 2025-07-10
🔗来源: https://cen.acs.org/synthesis/Skeletal-editing-cutpaste-chemistry/103/web/2025/07

New myosin inhibitors can drug the brain without stopping the heart 新的肌氨酸抑制剂可以在不阻断心脏的情况下给大脑下药

Potential indications for these more-specific compounds include brain cancer and methamphetamine addiction （这些较特定化合物的潜在迹象包括脑癌和甲基苯丙胺上瘾）
📰来源: C&EN
📆 日期: 2025-07-09
🔗来源: https://cen.acs.org/biological-chemistry/New-myosin-inhibitors-drug-brain/103/web/2025/07

Chemistry in Pictures: Janus double emulsions 图片中的化学: Janus双乳胶

Submitted by Narani Rakesh, National Dong Hwa University （国家东华大学Narani Rakesh提交）
📰来源: C&EN
📆 日期: 2025-07-02
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Janus-double-emulsions/103/web/2025/06

Chemistry in Pictures: Porphyrin pellets 图片中的化学: Porphyrin 粒

📰来源: C&EN
📆 日期: 2025-06-18
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Porphyrin-pellets/103/web/2025/06

Magnetic stirrers linked to issues with reproducing chemistry results 与产生化学结果的问题有关的磁搅动器

From the lab that found impurities on your stir bar—your flask’s placement on a stirrer plate can mess with your reaction too （从实验室里发现了你的搅拌棒上的杂质... 你的瓶子放在搅拌盘上也会弄乱你的反应）
📰来源: C&EN
📆 日期: 2025-06-17
🔗来源: https://cen.acs.org/research-integrity/reproducibility/Magnetic-stirrers-linked-issues-reproducing/103/web/2025/06

Modified polymer could help people with PEG allergies 改良聚合物可以帮助PEG过敏症患者

Tweaking the polyethylene glycol layer around lipid nanoparticles could prevent rare reactions to drugs, including some COVID-19 vaccines （将聚乙烯甘醇层绕入脂质纳米粒子可以防止对药物的稀有反应,包括一些COVID-19疫苗.）
📰来源: C&EN
📆 日期: 2025-06-16
🔗来源: https://cen.acs.org/synthesis/medicinal-chemistry/Modified-polymer-help-people-PEG/103/web/2025/06

Honeywell to buy Johnson Matthey’s catalyst technology unit Johnson Matthey的催化剂技术单位

The conglomerate says the purchase will complement its UOP chemical technology business （集团说,购买将补充其UOP化学技术业务）
📰来源: C&EN
📆 日期: 2025-06-09
🔗来源: https://cen.acs.org/synthesis/catalysis/Honeywell-buy-Johnson-Mattheys-catalyst/103/web/2025/05

‘Perplexanes’ achieve mind-bending molecular topology `三聚烷 ' 实现心动分子地貌

Zirconium helps to weave entangled nanocarbon cages in high yields （ium有助于高产量地将被缠绕的纳米碳笼编织在一起）
📰来源: C&EN
📆 日期: 2025-06-09
🔗来源: https://cen.acs.org/synthesis/Perplexanes-achieve-mind-bending-molecular/103/web/2025/06

Chemistry in Pictures: Ruby shards 图片中的化学: Ruby shards

📰来源: C&EN
📆 日期: 2025-06-05
🔗来源: https://cen.acs.org/materials/electronic-materials/Chemistry-Pictures-Ruby-shards/103/web/2025/06

Protein catalysts designed to do non-natural chemistry 用于非自然化学的蛋白质催化剂

Researchers couple AI and chemical know-how to create tools for cyclopropanation and silylation reactions （研究人员对人工智能和化学专门技能进行配对,以创建环传播和闪烁反应的工具）
📰来源: C&EN
📆 日期: 2025-05-26
🔗来源: https://cen.acs.org/synthesis/biocatalysis/Protein-catalysts-designed-non-natural/103/web/2025/05

Chemistry in Pictures: Color control 图片中的化学: 色彩控制

📰来源: C&EN
📆 日期: 2025-05-15
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Color-control/103/web/2025/05

Osmium ensnared in a hydrocarbon ring 被碳氢化合物圈所困

Chemists make new class of planar organometallic compounds （化学家制造出新种类的板状有机金属化合物）
📰来源: C&EN
📆 日期: 2025-05-01
🔗来源: https://cen.acs.org/synthesis/Osmium-ensnared-hydrocarbon-ring/103/web/2025/05

Glitter and glow 闪闪发光

📰来源: C&EN
📆 日期: 2025-04-22
🔗来源: https://cen.acs.org/materials/nanomaterials/Glitter-glow/103/web/2025/04

Going big with δ-cyclodextrin

The first scaled-up synthesis of this 9-sugar ring could expand its applications （这个9糖圈的首次放大合成 可以扩大其应用）
📰来源: C&EN
📆 日期: 2025-04-14
🔗来源: https://cen.acs.org/synthesis/process-chemistry/bigcyclodextrin/103/web/2025/04

More cross-coupling with less metal 与金属较少的交叉连接

Low-cost sodium salt may enable chemists to assemble molecules more efficiently and safely （低成本钠盐可使化学家更有效地和安全地组装分子）
📰来源: C&EN
📆 日期: 2025-04-10
🔗来源: https://cen.acs.org/synthesis/catalysis/cross-coupling-less-metal/103/web/2025/03

Interstellar benzene likely can’t form as predicted 星际苯不可能像预测的那样形成

Experimental data refute decades-old theoretical ion-molecule reaction pathway of benzene formation in space （实验数据反驳了数十年的理论离子-分子反应途径）
📰来源: C&EN
📆 日期: 2025-04-03
🔗来源: https://cen.acs.org/acs-news/meetings/Interstellar-benzene-likely-t-form/103/web/2025/03

Chemists create matchmaking app for biocatalysis 化学家为生物催化创建匹配应用

Machine learning model Catnip helps chemists find biocatalysts to try in synthesis （机器学习模型 Catnip 帮助化学家找到生物催化剂 尝试合成）
📰来源: C&EN
📆 日期: 2025-04-03
🔗来源: https://cen.acs.org/acs-news/acs-meeting-news/Chemists-create-matchmaking-app-biocatalysis/103/web/2025/03

Chemistry in Pictures: Beautiful waste 图片中的化学:美丽的废物

📰来源: C&EN
📆 日期: 2025-04-02
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Beautiful-waste/103/web/2025/04

Chemistry in Pictures: Coralline crystals 图片中的化学:珊瑚晶体

📰来源: C&EN
📆 日期: 2025-03-28
🔗来源: https://cen.acs.org/synthesis/Chemistry-Pictures-Coralline-crystals/103/web/2025/03

2 ways to stick nitrogen into alkenes 将氮气粘入烷烃的两种方法

2 new methods expand synthetic chemists’ options for cutting double bonds and installing new bonds to nitrogen （2个新方法扩大了合成化学家削减双键和安装氮新键的选择）
📰来源: C&EN
📆 日期: 2025-03-14
🔗来源: https://cen.acs.org/synthesis/2-ways-stick-nitrogen-alkenes/103/web/2025/03

Berkelocene puts exotic berkelium in a sandwich 贝克洛辛在三明治里放出异国情调的贝克来

Researchers find bonding surprises at the extreme end of organometallic chemistry （研究人员在有机金属化学的极端端 发现了令人惊奇的惊喜）
📰来源: C&EN
📆 日期: 2025-02-28
🔗来源: https://cen.acs.org/analytical-chemistry/Berkelium-carbon-bonding/103/web/2025/02

Carbon-atom transfer with spiro style 有斯皮罗风格的碳原子转移

New reagent sticks carbon atoms onto olefins to create unusual 3D structures （新的试剂将碳原子粘接到烯烃上,以创建不寻常的立体结构）
📰来源: C&EN
📆 日期: 2025-02-24
🔗来源: https://cen.acs.org/synthesis/Carbon-atom-transfer-spiro-style/103/web/2025/02

Something smells off about this enzyme 有东西闻到这个酶的味道

A newly discovered enzyme swiftly makes a stink （新发现的酶会很快发臭）
📰来源: C&EN
📆 日期: 2025-02-21
🔗来源: https://cen.acs.org/biological-chemistry/biochemistry/Something-smells-off-enzyme/103/web/2025/02

A new path to elusive fluorinated oxetanes 通向难以捉摸的氟化牛的一条新路

Copper catalyst surgically inserts difluorinated carbene into small heterocycles （铜催化剂外科手术将二氟化碳插入小型异能循环）
📰来源: C&EN
📆 日期: 2025-02-20
🔗来源: https://cen.acs.org/synthesis/new-path-elusive-fluorinated-oxetanes/103/web/2025/02

New method makes high-entropy oxides in a flash 新方法在闪光中产生高直径氧化物

Photoflash-driven synthesis is cheap, fast, and allows variety of substrates （光发驱动的合成是便宜的、快的,并允许各种底物）
📰来源: C&EN
📆 日期: 2025-02-11
🔗来源: https://cen.acs.org/synthesis/New-method-makes-high-entropy/103/web/2025/02

Mattiq and Heraeus partner on low-iridium electrocatalysis Mattiq和Heraeus搭档进行低纤维电解

📰来源: C&EN
📆 日期: 2025-02-07
🔗来源: https://cen.acs.org/synthesis/catalysis/Mattiq-Heraeus-partner-low-iridium/103/i3

Ecovyst and ChiralVision team up for enzyme immobilization Ecovyst和Chiral Vision 组队进行酶活化

📰来源: C&EN
📆 日期: 2025-02-07
🔗来源: https://cen.acs.org/synthesis/catalysis/Ecovyst-ChiralVision-team-enzyme-immobilization/103/i3

How Japan took the lead in the race to discover element 119 日本是如何率先发现119元素的

After a breakdown in US-Russia relations, Riken finds itself ahead of its rivals. And Lawrence Berkeley National Laboratory chases element 120 （在美俄关系破裂后,里肯发现自己领先对手. 而劳伦斯伯克利国家实验室 追逐元素120）
📰来源: C&EN
📆 日期: 2025-01-24
🔗来源: https://cen.acs.org/physical-chemistry/periodic-table/Japan-took-lead-race-discover/103/i2

Chemistry in Pictures: The littlest honeycomb 图片中的化学: 最小的蜂窝

📰来源: C&EN
📆 日期: 2025-01-13
🔗来源: https://cen.acs.org/materials/nanomaterials/Chemistry-Pictures-littlest-honeycomb/103/web/2025/01

Electrosynthesis goes wireless 电路合成无线

Light-powered microelectronics enable high-throughput experimentation （光能微电子可以进行高通量实验）
📰来源: C&EN
📆 日期: 2025-01-08
🔗来源: https://cen.acs.org/synthesis/Electrosynthesis-goes-wireless/103/web/2025/01

Skeletal editing strategy makes room for more nitrogen 骨骼编辑策略可以增加氮气

Sulfenylnitrene reagent expands N-heterocycles by a single N atom （磺酰硝基苯试剂由单一的N原子来扩大N-异氧循环）
📰来源: C&EN
📆 日期: 2025-01-06
🔗来源: https://cen.acs.org/synthesis/reagents/Skeletal-editing-strategy-makes-room/103/web/2025/01