项目整合精选

聚焦新型临床类新产品的整合与转化. 在创新药研发领域，传统的“单一产品、单打独斗”模式正在被一种更系统化的“项目整合”思维所取代。项目整合的核心，在于将散落在研发早期、中期的创新资产，通过资金、临床资源、产业生态等多维度要素的有机组合，实现从“科学发现”到“临床价值”，再到“商业成功”的跨越。研发与商业的战略整合：从“资产思维”到“组合思维”它要求我们超越单个分子的视野，拥抱一个由技术创新、临床需求、资本支持和商业洞察共同构成的复杂网络。在这个网络中，成功的标准不再是单一的“获批上市”，而是能否通过高效的整合，将科学上的突破，转化为临床上真正可及、商业上可持续、能够惠及患者的解决方案。近年来，药物发现已从传统的小分子化药拓展至更多元的分子类型，这些新型API在项目整合中呈现出独特的开发范式，项目整合的核心挑战在于递送系统的设计与肝外靶向能力的突破。
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

项目整合精选

Doripenem, S-4661

多利培南Chemical Name: (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[2(S)-(sulfamoylaminomethyl)pyrrolidin-4(S)-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid inner salt
CAS No. 148016-81-3
项目整合开发状态: ...
参考文献标题:A pyrrolidylthiocarbapenem derivative
文献作者:Nishitani,Y.; Irie,T.; Nishino,Y.(Shionogi & Co.Ltd.)
参考来源:EP 0528678; JP 1993294970; US 5317016

Doxpicodin hydrochloride(former USAN), Doxpicomine hydrochloride, LY-108380

多匹可明多匹可明Chemical Name: 1-(1,3-Dioxan-5-yl)-N,N-dimethyl-1-(3-pyridyl)methanamine hydrochloride
CAS No. 69494-04-8, 62904-73-8 (diHCl), 62904-71-6 (free base)
项目整合开发状态: Biological Testing
项目研究...
参考文献标题:Various 5-substituted and 2,5-disubstituted 1,3-dioxanes,a new class of analgesic agents
文献作者:Booher,R.N.; et al.
参考来源:J Med Chem 1977,20(7),885

Flavalfate, Dosmalfate, F-3616M, F-3616, Diotul

多司马酯Chemical Name: [mu7-[7-[[6-O-(6-Deoxy-2,3,4-tri-O-sulfo-alpha-L-mannopyranosyl)-2,3,4-tri-O-sulfo-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-[4-methoxy-3-(sulfooxy)phenyl]-4H-1-benzopyran-4-onato(7-)]...
参考文献标题:Sulfated diosmin deriv.
文献作者:Orjales-Venero,A.; Mosquera-Pestana,R.(FAES)
参考来源:EP 0558435; ES 2041216; JP 1994008677; US 5296469

Dopexamine, FPL-60278

多培沙明盐酸多培沙明Chemical Name: 4-[2-[[6-[(2-Phenylethyl)amino]hexyl]amino]ethyl]-1,2-benzenediol; 4-[2-[[(6-Phenethylamino)hexyl]amino]ethyl]pyrocathecol; N-(2-Phenylethyl)-N'-[2-(3,4-dihydroxyphenyl)ethyl]...
参考文献标题:Phenylethylamine derivatives and pharmaceutical use
文献作者:Farmer,J.B.; Ince,F.; Brown,R.A.; Dixon,J.(Rh鬾e-Poulenc Rorer Ltd.)
参考来源:CA 1191846; EP 0072061; US 5013760

Doxacurium chloride, BW-A938U, Nuromax

多库酯钠Chemical Name: trans,trans-2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy-3,1-propanediyl)]bis[6,7,8-trimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolinium] dichloride; (...
参考文献标题:Long duration neuromuscular blocking agents,pharmaceutical compsns.containing them and processes for their preparation
文献作者:El-Sayad,H.A.; Yeowell,D.A.; Swaringen,R.A.Jr.(GlaxoSmithKline plc)
参考来源:EP 0054309; US 4701460

新产品编号:55879

多柔比星-薮酮-镌酰-马雷酰亚胺Chemical Name: N'-[1-[4(S)-(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyloxy)-2(S),5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-2-yl]-2-hydroxyethylidene]-...
参考文献标题:Thioether conjugates
文献作者:Willner,D.; Trail,P.A.; King,D.H.; Hofstead,S.J.; Greenfield,R.S.; Braslawsky,G.R.(Bristol-Myers Squibb Co.)
参考来源:EP 0554708; JP 1994025012; US 5622929

Dromoprednate, Ro-12-7024

多泼尼酯Chemical Name: 11beta-Hydroxy-17a-(1-oxobutoxy)-D-homopregna-1,4-diene-3,20-dione; 11beta,17aalpha-Dihydroxy-D-homopregna-1,4-diene-3,20-dione 17a-butyrate; 17aalpha-Butyryloxy-11beta-hydroxy-D-ho...
参考文献标题:D-Homopregnanes
文献作者:F黵st,A.; Alig,L.; Kerb,U.; M黮ler,M.; Wiechert,R.; Kieslich,K.(Hoffmann-La Roche,Inc.)
参考来源:US 4202841

Docetaxol, Docetaxel, XRP-6976L, NSC-628503, RP-56976, Taxotere

多烯紫杉醇;多西他赛三水多烯紫杉醇 Chemical Name: N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol; [2aR-[2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11beta,12alpha,12aalpha,12balpha]]-beta-(tert-Butoxycarbon...
参考文献标题:Process for preparing derivs.of baccatine III and of 10-deacetyl baccatine III
文献作者:Colin,M.; Guenard,D.; Gueritte-Voegelein,F.; Potier,P.(Aventis SA)
参考来源:US 4924012

Doxofylline, DO-309, ABC-1213, ABC-12/3, Maxivent, Ventax, Ansimar

多索茶碱Chemical Name: 2-(7'-Theophyllinemethyl)-1,3-dioxolane; 7-(1,3-Dioxolan-2-ylmethyl)theophylline; 7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS No. 69975-86-6
项...
参考文献标题:Pharmaceutical composition with anti-bronchospasmodic and anti-tussive activity
文献作者:Franzone,J.S.; Tamietto,T.(Istituto Biologico Chemioterapico "ABC" SpA)
参考来源:BE 0868556; DE 2827497; FR 2421614; GB 1582510; JP 1123066C; JP 54138127; JP 57015088B; NL 7807152; US 4187308

Docebenone, A-61589, AA-861

多西苯醌Chemical Name: 2-(12-Hydroxy-5,10-docedadiynyl9-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione; 2,5,6-Trimethyl-3-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone; 2,3,5-Trimethyl-6-(12-hydroxy-5,10-...
参考文献标题:Quinone compounds and their use in suppressing the production of SRS-A in mammals
文献作者:Terao,S.; Shiraishi,M.; Maki,Y.(Takeda Chemical Industries,Ltd.)
参考来源:EP 0038160; GB 2074158; JP 81145280; JP 81154433; JP 82109739