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临床前CDMO研发化合物筛选
Riociguat (BAY 63-2521)
中文名称: 利奥西呱
CAS号:625115-55-1
分子式: C20H19FN8O2 分子量: 422.42
产品形式: free base
研发状态: Not yet recruiting
研发用途: Migraine Without Aura
研究机构: Danish Headache Center
研发日期: April 1 2023
研发阶段: Not Applicable
Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension.
Methacholine chloride
中文名称:氯化乙酰甲胆碱
CAS号:62-51-1
分子式: C8H18NO2.Cl 分子量: 195.69
产品形式: chloride
研发状态: Completed
研发用途: Endothelial Dysfunction
研究机构: Indiana University; National Heart Lung and Blood Institute (NHLBI)
研发日期: Nov-03
研发阶段: Not Applicable
Methacholine (Mecholyl, Acetyl-β-methylcholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system but has little effects on the nicotinic receptors.
Gastrodin
中文名称:天麻素
CAS号:62499-27-8
分子式: C13H18O7 分子量: 286.28
产品形式: free base
研发状态: Unknown status
研发用途: Cognitive Decline
研究机构: Huazhong University of Science and Technology
研发日期: Feb-06
研发阶段: Phase 4
Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.
Dimethyl Fumarate
中文名称: 富马酸二甲酯
CAS号:624-49-7
分子式: C6H8O4 分子量: 144.13
产品形式: free base
研发状态: Not yet recruiting
研发用途: Pancreatic Cancer
研究机构: Tianjin Medical University Cancer Institute and Hospital
研发日期: May 1 2024
研发阶段: Phase 2 : Phase 3
Dimethyl fumarate (DMF,Tecfidera,BG-12) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression.
Edetate calcium disodium
中文名称:依地酸钙钠
CAS号:62-33-9
分子式: C10H12CaN2Na2O8 分子量: 374.27
产品形式: disodium salt
研发状态: Withdrawn
研发用途: Heavy Metal Toxicity
研究机构: Mt. Sinai Medical Center Miami
研发日期: Jul-17
研发阶段: Phase 4
Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning.
Dopamine HCl
中文名称:盐酸多巴胺
CAS号:62-31-7
分子式: C8H11NO2.HCl 分子量: 189.64
产品形式: Hydrochloride
研发状态: Not yet recruiting
研发用途: Depression
研究机构: University College London; King''s College London; Queen Mary University of London; University of Dublin Trinity College
研发日期: Jun-24
研发阶段: Not Applicable
Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
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