其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Methenolone CAS Registry Number: 153-00-4 美替诺龙

CAS Name: (5a,17b)-17-Hydroxy-1-methylandrost-1-en-3-one
Additional Names: 1-methyl-D1-androsten-17b-ol-3-one; méténolone
Percent Composition: C 79.42%, H 10.00%, O 10.58%
Literature References: Prepn: Wiechert, Kaspar, Ber. 93, 1710 (1960); Popper, DE 1023764 (1958 to Schering, AG).

Sulfaloxic Acid CAS Registry Number: 14376-16-0 磺胺洛西酸

CAS Name: 2-[[[4-[[[[(Hydroxymethyl)amino]carbonyl]amino]sulfonyl]phenyl]amino]carbonyl]benzoic acid
Additional Names: 4'-(carbamoylsulfamoyl)phthalanilic acid hydroxymethyl derivative; 4'-(car...
Literature References: Prepn: Wiedemann, Strassburger, DE 960190 (1957 to von Heyden), C.A. 53, 6547i (1959).

Ethambutol CAS Registry Number: 74-55-5 乙胺丁醇

CAS Name: 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol
Additional Names: (+)-2,2'-(ethylenediimino)di-1-butanol; d-N,N'-bis(1-hydroxymethylpropyl)ethylenediamine; EMB
Percent Composition: C 58....
Literature References: Prepn: Wilkinson et al., J. Am. Chem. Soc. 83, 2212 (1961); eidem, J. Med. Chem. 5, 835 (1962). Pharmacology: Kulig et al., Diss. Pharm. Pharmacol. 23, 463 (1971), C.A. 76, 81239d (1972). Comprehensive description: C. S. Lee, L. Z. Benet, Anal. Profiles Drug Subs. 7, 231-249 (1978). Mechanism of action: W. H. Beggs in Antibiotics vol. 5(pt. 1), F. E. Hahn, Ed. (Springer-Verlag, New York, 1979) pp 43-66.

Titanocene Dichloride CAS Registry Number: 1271-19-8 二氯二茂钛

CAS Name: Dichlorobis(h5-2,4-cyclopentadien-1-yl)titanium
Additional Names: dichlorodi-p-cyclopentadienyltitanium; biscyclopentadienyltitanium(IV) dichloride
Percent Composition: C 48.24%, H...
Literature References: Prepn: Wilkinson, Birmingham, J. Am. Chem. Soc. 76, 4281 (1954). Structure: Clearfield et al., Can. J. Chem. 53, 1622 (1975).

Tiadenol CAS Registry Number: 6964-20-1 2,2'-(十亚甲基二硫代)二乙醇

CAS Name: 2,2'-[1,10-Decanediylbis(thio)]bisethanol
Additional Names: 2,2'-(decamethylenedithio)diethanol; 1,10-bis(2-hydroxyethylthio)decaneTrademarks: Delipid (Coop. Farm.); Eulip (SIT); Fonl...
Literature References: Prepn: Williams, Cossar, US 3021215 (1962 to Eastman Kodak); Lafon, DE 2038836 (1971 to Orsymonde), C.A. 75, 35528d (1971). Series of articles on pharmacology, metabolism, and toxicology: Therapie 27, 395-444 (1972).

Dimethisoquin CAS Registry Number: 86-80-6 奎尼卡因

CAS Name: 2-[(3-Butyl-1-isoquinolinyl)oxy]-N,N-dimethylethanamine
Additional Names: 3-butyl-1-[2-(dimethylamino)ethoxy]isoquinoline; 1-(b-dimethylaminoethoxy)-3-n-butylisoquinoline; quinisocain...
Literature References: Prepn: Wilson et al., J. Am. Chem. Soc. 71, 937 (1949); Anderson et al., J. Am. Pharm. Assoc. Sci. Ed. 41, 643 (1952); Ullyot, US 2612503 (1952 to SK F). Clinical studies: Robinson: South. Med. J. 50, 367 (1957). Toxicity study: Fellows, Macko, J. Pharmacol. Exp. Ther. 103, 306 (1951).

Dicofol CAS Registry Number: 115-32-2 三氯杀螨醇

CAS Name: 4-Chloro-a-(4-chlorophenyl)-a-(trichloromethyl)benzenemethanol
Additional Names: 4,4'-dichloro-a-(trichloromethyl)benzhydrol; 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethanol; di(p-chlo...
Literature References: Prepn: Wilson, Craig, US 2812280; Wilson, Wolffe, US 2812362 (both 1957 to Rohm Haas); Bergmann, Kaluszyner, J. Org. Chem. 23, 1306 (1958); GB 831421 (1960 to Metal Thermit Corp.). Miticidal activity: J. S. Baker, F. B. Maughan, J. Econ. Entomol. 49, 458 (1956). Toxicology: R. B. Smith et al., Toxicol. Appl. Pharmacol. 1, 119 (1959). Metabolism: J. R. Brown et al., ibid. 15, 30 (1969); K. Tabata et al., Appl. Entomol. Zool. 14, 490 (1979). Review of carcinogenic risk: IARC Monographs 30, 87-101 (1983).

Allocholesterol CAS Registry Number: 517-10-2 别胆固醇

CAS Name: (3b)-Cholest-4-en-3-ol
Additional Names: coprostenol; 4:5-coprosten-3-ol
Percent Composition: C 83.87%, H 11.99%, O 4.14%
Literature References: Prepn: Windaus, Ann. 453, 101 (1927); Schoenheimer, Evans, J. Biol. Chem. 114, 567 (1936). Sepn from cholesterol: Stoll, Z. Physiol. Chem. 246, 10 (1937).

p-Diaminoazobenzene CAS Registry Number: 538-41-0 对二氨基偶氮苯

CAS Name: 4,4'-Azobisbenzenamine
Additional Names: 4,4'-azodianiline; p-azoaniline; 4,4'-diaminoazobenzene
Percent Composition: C 67.91%, H 5.70%, N 26.40%
Literature References: Prepn: Witt, Kopetschini, Ber. 45, 1136 (1912); Brode et al., J. Am. Chem. Soc. 77, 2762 (1955). Lab procedure starting with p-aminoacetanilide; Santurri et al., Org. Synth. 40, 18 (1960).

Sodium Tetraphenylborate CAS Registry Number: 143-66-8 四苯硼钠

Additional Names: Tetraphenylboron sodium
Trademarks: Kalignost
Percent Composition: C 84.23%, H 5.89%, B 3.16%, Na 6.72%
Literature References: Prepn: Wittig, Raff, Ann. 573, 195 (1950); US 2853525 (1958); Heyl, GB 705719 (1954); Kozlova, Pal'm, Zh. Obshch. Khim. 31, 2922 (1961); Holtzapfel, Richter, ibid. 32, 1358 (1962).