其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
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其它产品项目整合

Ferric Formate CAS Registry Number: 555-76-0

Percent Composition: C 18.87%, H 1.58%, Fe 29.25%, O 50.29%
Literature References: Prepn: Weinland, Reihlin, Ber. 46, 3144 (1913); Starke, J. Inorg. Nucl. Chem. 25, 823 (1963). May contain 1 or 2 H2O.

DBMC CAS Registry Number: 497-39-2 4,6-二叔丁基间甲酚

CAS Name: 2,4-Bis(1,1-dimethylethyl)-5-methylphenol
Additional Names: 4,6-di-tert-butyl-m-cresol; 3-methyl-4,6-di-tert-butylphenol
Percent Composition: C 81.76%, H 10.98%, O 7.26%
Literature References: Prepn: Weinrich, Ind. Eng. Chem. 35, 264 (1943).

Metanil Yellow CAS Registry Number: 587-98-4 酸性金黄G

CAS Name: 3-[[4-(Phenylamino)phenyl]azo]benzenesulfonic acid monosodium salt
Additional Names: C.I. Acid Yellow 36; m-[(p-anilinophenyl)azo]benzenesulfonic acid sodium salt; sodium salt of meta...
Literature References: Prepn: Welcher, Organic Analytical Reagents vol. 4 (Van Nostrand, 1948) p 516; Colour Index vol. 4 (3rd ed., 1971) p 4045.

Benzylhydrochlorothiazide CAS Registry Number: 1824-50-6 6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺

CAS Name: 6-Chloro-3,4-dihydro-3-(phenylmethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Additional Names: 3-benzyl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-d...
Literature References: Prepn: Werner et al., J. Am. Chem. Soc. 82, 1161 (1960); Novello et al., J. Org. Chem. 25, 970 (1960); Ugi, US 3108097 (1963).

a -Naphtholphthalein CAS Registry Number: 596-01-0 α-萘酚酞指示剂

CAS Name: 3,3-Bis(4-hydroxynaphthalenyl)-1(3H)-isobenzofuranone
Additional Names: 3,3-bis(4-hydroxy-1-naphthyl)phthalide; di-p-a-naphtholphthalide; p-a-naphtholphthalein
Percent Composition:...
Literature References: Prepn: Werner, J. Chem. Soc. 113, 20 (1918). Commercial prepn contains a small amount of the isomeric 3,3-bis(2-hydroxy-1-naphthyl)phthalide.

Dydrogesterone CAS Registry Number: 152-62-5 地屈孕酮

CAS Name: (9b,10a)-Pregna-4,6-diene-3,20-dione
Additional Names: 10a-pregna-4,6-diene-3,20-dione; 6-dehydro-retro-progesterone; 10a-isopregnenone
Trademarks: Dufaston (ISM); Duphaston (Roxan...
Literature References: Prepn: Westerhof, Reerink, Rec. Trav. Chim. 79, 771 (1960); Rappoldt, Westerhof, ibid. 80, 43 (1961).

Amolanone CAS Registry Number: 76-65-3 阿莫拉酮

CAS Name: 3-[2-(Diethylamino)ethyl]-3-phenyl-2(3H)-benzofuranone
Additional Names: 3-(2-diethylaminoethyl)-2-oxo-3-phenyl-2,3-dihydrobenzofuran; g-diethylamino-a-(o-hydroxyphenyl)-a-phenylbutyr...
Literature References: Prepn: Weston, Brownell, J. Am. Chem. Soc. 74, 653 (1952).

Homochlorcyclizine CAS Registry Number: 848-53-3 苯甲庚嗪

CAS Name: 1-[(4-Chlorophenyl)phenylmethyl]hexahydro-4-methyl-1H-1,4-diazepine
Additional Names: N-(p-chlorobenzhydryl)-N'-methylhomopiperazine; 1-(4-chlorodiphenylmethyl)-4-methyl-2,3,4,5,6,7-h...
Literature References: Prepn: Weston, Sommers, US 2655498 (1953 to Abbott); eidem, J. Am. Chem. Soc. 76, 5805 (1954). HPLC determn of enantiomers in urine: M. Nishikata et al., J. Chromatogr. 612, 239 (1993).

Oxanamide CAS Registry Number: 126-93-2 奥沙那胺

CAS Name: 2-Ethyl-3-propyloxiranecarboxamide
Additional Names: 2,3-epoxy-2-ethylhexanamide; 2-ethyl-3-propylglycidamide; 2-ethyl-3-propyl-2,3-epoxypropionamide
Percent Composition: C 61.12%,...
Literature References: Prepn: Wheeler et al., J. Org. Chem. 25, 1021 (1960).

Cyclopenthiazide CAS Registry Number: 742-20-1 环戊噻嗪

CAS Name: 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Additional Names: 6-chloro-3-cyclopentylmethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothi...
Literature References: Prepn: Whitehead et al., J. Org. Chem. 26, 2814 (1961); BE 587225 (1960 to Ciba). Pharmacology: W. E. Barrett et al., Arch. Int. Pharmacodyn. 131, 325 (1961).