Properties: mp 87.5-88.8°. [a]D25 +13.7° (c = 2 in water). Sol in chloroform, methylene chloride; less sol in benzene; sparingly sol in water.
Melting point: mp 87.5-88.8°
Optical Rotation: [a]D25 +13.7° (c = 2 in water)
Derivative Type: Dihydrochloride
CAS Registry Number: 1070-11-7
Trademarks: Dexambutol (L'Arguenon); Ebutol (Kaken); Etibi (Gerot); Etapiam (Piam); Myambutol (Wyeth); Mycobutol (Cadila); Sural (Chinoin); Tibutol (Bracco)
Percent Composition: C 43.32%, H 9.45%, N 10.10%, O 11.54%, Cl 25.58%
Properties: mp 198.5-200.3°; also reported as mp 201.8-202.6°. [a]D25 +7.6° (c = 2 in water). Sol in water, DMSO; sparingly sol in ethanol; difficultly sol in acetone, chloroform.
Melting point: mp 198.5-200.3°; mp 201.8-202.6°
Optical Rotation: [a]D25 +7.6° (c = 2 in water)
Derivative Type: Mixture with isoniazid methane sulfonate
CAS Registry Number: 41663-50-7
Additional Names: (+)-2,2-(Ethylenediimino)dibutanol diisoniazide methanesulfonate; isobutol
Trademarks: Isoetam (Ferrer)
Literature References: Prepn: C. Ferrer-Salat et al.,
BE
753862;
US
3718655 (1971, 1973 both to Lab. Ferrer).
Properties: White powder, crystallizes as needles, mp 121-122° (dec). Sol in water, methanol, N,N-dimethylformamide. Insol in ethanol, ethyl ether, chloroform. uv max: 265 nm. [a]D20 +3° (c = 5% in water). LD50 in mice (g/kg): 2.800 orally; 2.210 i.p. (Ferrer-Salat).
Melting point: mp 121-122° (dec)
Optical Rotation: [a]D20 +3° (c = 5% in water)
Absorption maximum: uv max: 265 nm
Toxicity data: LD50 in mice (g/kg): 2.800 orally; 2.210 i.p. (Ferrer-Salat)
Therap-Cat: Antibacterial (tuberculostatic).
Keywords: Antibacterial (Tuberculostatic).
产品链接: 74-55-5››