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  • 其它产品项目整合
    • 项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
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    其它产品项目整合

  • Chlophedianol CAS Registry Number: 791-35-5 氯苯达诺


    CAS Name: 2-Chloro-a-[2-(dimethylamino)ethyl]-a-phenylbenzenemethanol
    Additional Names: 2-chloro-a-(2-dimethylaminoethyl)benzhydrol; 1-o-chlorophenyl-1-phenyl-3-dimethylamino-1-propanol; 1-phen...
    Literature References: Prepn: Henecka, Lorenz, DE 1083277 (1960); Lorenz et al., US 3031377 (1962, both to Bayer).

  • Cryofluorane CAS Registry Number: 76-14-2 1,2-二氯四氟乙烷


    CAS Name: 1,2-Dichloro-1,1,2,2-tetrafluoroethane
    Trademarks: Freon 114 (DuPont); Frigen 114 (Hoechst); Arcton 114 (ICI)
    Percent Composition: C 14.05%, Cl 41.48%, F 44.46%
    Literature References: Prepn: Henne, Org. React. 2, 49 (1944).

  • Dichlorodifluoromethane CAS Registry Number: 75-71-8 二氯二氟甲烷


    Additional Names: Difluorodichloromethane
    Trademarks: Arcton 12 (ICI); Freon 12 (DuPont); Frigen 12 (Hoechst); Genetron 12 (AlliedSignal); Halon; Isotron 2
    Percent Composition: C 9.93%, Cl 5...
    Literature References: Prepn: Henne, Org. React. 2, 49 (1944); Swarts, Chem. Zentralbl. 1907, II, 581. Manuf: Faith, Keyes Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 325-330.

  • Trichlorofluoromethane CAS Registry Number: 75-69-4 三氯氟甲烷


    Additional Names: Trichloromonofluoromethane; fluorotrichloromethane; fluorocarbon 11; FC 11
    Trademarks: Arcton 11 (ICI); Freon 11 (DuPont); Frigen 11 (Hoechst)
    Percent Composition: C 8.74%,...
    Literature References: Prepn: Henne, Org. React. 2, 64 (1944). Manuf: Faith, Keyes Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 325-330.

  • Fluoxymesterone CAS Registry Number: 76-43-7 氟甲睾酮


    CAS Name: (11b,17b)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
    Additional Names: 11b,17b-dihydroxy-9a-fluoro-17a-methyl-4-androsten-3-one; 9a-fluoro-11b-hydroxy-17a-methyltestosterone...
    Literature References: Prepn: Herr et al., J. Am. Chem. Soc. 78, 501 (1956). cf. Herr, US 2813881 (1957 to Upjohn). Comprehensive description: J. Kirschbaum, Anal. Profiles Drug Subs. 7, 251-275 (1978).

  • Chlormidazole CAS Registry Number: 3689-76-7 氯苄达唑


    CAS Name: 1-[(4-Chlorophenyl)methyl]-2-methyl-1H-benzimidazole
    Additional Names: 1-(p-chlorobenzyl)-2-methylbenzimidazole; 2-methyl-1-(p-chlorobenzyl)benzimidazole; clomidazole
    Percent Compo...
    Literature References: Prepn: Herrling et al., US 2876233 (1959 to Grünenthal).

  • Indocyanine Green CAS Registry Number: 3599-32-4 吲哚菁绿


    CAS Name: 2-[7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium inner salt, sodium salt
    Additional Name...
    Literature References: Prepn: Heseltine, Brooker, US 2895955 (1959 to Kodak).

  • Lethane® 60 (Rohm & Haas) CAS Registry Number: 301-11-1 2-硫氰酸基乙基月桂酸酯


    CAS Name: Dodecanoic acid 2-thiocyanatoethyl ester
    Additional Names: lauric acid 2-thiocyanatoethyl ester; lauric acid ester with 2-hydroxyethyl thiocyanate; 2-thiocyanoethyl dodecanoate; 2-thi...
    Literature References: Prepn: Hester, US 2220521 (1941 to Rohm Haas). Toxicity study: E. E. Kenaga, Bull. Entomol. Soc. Am. 12, 161 (1966).

  • Salacetamide CAS Registry Number: 487-48-9 醋水杨胺


    CAS Name: N-Acetyl-2-hydroxybenzamide
    Additional Names: N-acetylsalicylamide; acetsalicylamide
    Trademarks: Actylamide (Rougier)
    Percent Composition: C 60.33%, H 5.06%, N 7.82%, O 26.79%
    Literature References: Prepn: Hicks, J. Chem. Soc. 97, 1033 (1910); Anshutz, Mitarbeiter, Ann. 442, 25 (1925); BE 496438 (1950 to Soc. Belge de l'Azote Prod. Chim. Marly); Prost, Charlier, Experientia 18, 319 (1962). Metabolism: Rayet et al., Arch. Int. Pharmacodyn. Ther. 88, 159 (1951).

  • Tolycaine CAS Registry Number: 3686-58-6 托利卡因


    CAS Name: 2-(2-Diethylaminoacetamido)-m-toluic acid methyl ester
    Additional Names: 2-methyl-6-carbomethoxy-N-diethylaminoacetanilide; methyl 2-diethylaminoacetamido-m-toluate; 3-methyl-2-diethy...
    Literature References: Prepn: Hiltmann et al., DE 1018070 (1957 to Bayer); US 2921077 (1960 to Schenley).

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