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  • 其它产品项目整合
    • 项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
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    其它产品项目整合

  • Pipobroman CAS Registry Number: 54-91-1 哌泊溴烷


    CAS Name: 1,4-Bis-(3-bromo-1-oxopropyl)piperazine
    Additional Names: 1,4-bis-(3-bromopropionyl)piperazineTrademarks: Amedel (Dainippon); Vercyte (Abbott)
    Percent Composition: C 33.73%, H 4.53...
    Literature References: Prepn: Horrom, Carbon, DE 1138781 (1962 to Abbott), C.A. 58, 7955c (1963); Groszkowski, Rocz. Chem. 38, 229 (1964), C.A. 60, 14506a (1964). Structure-cytostatic effect studies: Groszkowski et al., J. Med. Chem. 11, 621 (1968); Oteleanu, Retezeanu, Farmacia (Bucharest) 16, 279 (1968), C.A. 69, 33591w (1968).

  • Piposulfan CAS Registry Number: 2608-24-4 哌泊舒凡


    CAS Name: 1,4-Bis[3-[(methylsulfonyl)oxy]-1-oxopropyl]piperazine
    Additional Names: 1,4-dihydracryloylpiperazine dimethanesulfonate; 1,4-bis(3-hydroxypropionyl)piperazine dimethanesulfonate; N,N...
    Literature References: Prepn: Horrom, Carbon, DE 1177162 (1964 to Abbott), C.A. 61, 13329a (1964).

  • Glycine Sulfate CAS Registry Number: 513-29-1 甘氨酸硫酸盐


    Additional Names: Triglycine sulfate
    Percent Composition: C 22.29%, H 5.30%, N 13.00%, O 49.49%, S 9.92%
    Literature References: Prepn: Horsford, Ann. 60, 1 (1846); see also Matthias, Miller, Remeika, Phys. Rev. 104, 849 (1956). Crystal growing during prepn: Konstantinova et al., Kristallografiya 4, 69-73 and 125-129 (1959).

  • Tropine Benzylate CAS Registry Number: 3736-36-5 托品醇二苯羟乙酸酯


    CAS Name: endo-a-Hydroxy-a-phenylbenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
    Additional Names: 1aH,5aH-tropan-3a-ol benzilate; benzilic acid 3a-tropanyl ester; glykin; BAT; BT...
    Literature References: Prepn: Hromatka et al., Monatsh. Chem. 83, 1321 (1952).

  • Anilinephthalein CAS Registry Number: 509-77-3 3,3-二(4-氨基苯基)苯酞


    CAS Name: 3,3-Bis(4-aminophenyl)-1(3H)-isobenzofuranone
    Additional Names: 3,3-bis(p-aminophenyl)phthalide
    Percent Composition: C 75.93%, H 5.10%, N 8.86%, O 10.11%
    Literature References: Prepn: Hubacher, J. Am. Chem. Soc. 73, 5885 (1951).

  • Phenolphthalol CAS Registry Number: 81-92-5 2-[双(4-羟基苯基)甲基]苄醇


    CAS Name: 2-[Bis(4-hydroxyphenyl)methyl]benzenemethanol
    Additional Names: o-[bis(p-hydroxyphenyl)methyl]benzyl alcohol; dihydroxyphenylmethenylbenzyl alcohol; 2-(4,4'-dihydroxybenzhydryl)benzyl...
    Literature References: Prepn: Hubacher, J. Am. Chem. Soc. 74, 5216 (1952); Schultz, Geller, Arch. Pharm. 288, 234 (1955); Bulcsu, DE 1141293 (1962 to Iromedica), C.A. 59, 1535b (1963).

  • Sulfamethizole CAS Registry Number: 144-82-1 磺胺甲二唑


    CAS Name: 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
    Additional Names: N1-(5-methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; 2-sulfanilamido-5-methyl-1,3,4-thiadiazole; 5-methyl-2...
    Literature References: Prepn: Hübner, US 2447702 (1948 to Lundbeck).

  • Captodiamine CAS Registry Number: 486-17-9 卡普托胺


    CAS Name: 2-[[[4-(Butylthio)phenyl]phenylmethyl]thio]-N,N-dimethylethanamine
    Additional Names: 2-[p-(butylthio)-a-phenylbenzylthio]-N,N-dimethylethylamine; p-butylmercaptobenzhydryl b-dimethyla...
    Literature References: Prepn: Hübner, Petersen, US 2830088 (1958). Pharmacological studies: R. Kopf, I. Moller-Nielsen, Arzneim.-Forsch. 8, 154 (1958).

  • A-Denopterin CAS Registry Number: 25663-23-4 N-[4-[[1-(2,4-二氨基-6-蝶啶基)乙基]甲基氨基]苯甲酰基]-L-谷氨酸


    CAS Name: N-[4-[[1-(2,4-Diamino-6-pteridinyl)ethyl]methylamino]benzoyl]-L-glutamic acid
    Additional Names: 4-amino-N10,9-dimethylpteroylglutamic acid
    Percent Composition: C 53.84%, H 5.16%, N...
    Literature References: Prepn: Hultquist et al., J. Am. Chem. Soc. 71, 619 (1949); Hultquist, Smith, GB 667098 (1952 to Am. Cyanamid).

  • Denopterin CAS Registry Number: 22006-84-4 N-(4-{[1-(2-氨基-4-氧代-1,4-二氢-6-蝶啶基)乙基](甲基)氨基}苯甲酰基)谷氨酸


    CAS Name: N-[4-[[1-(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)ethyl]methylamino]benzoyl]-L-glutamic acid
    Additional Names: 9,10-dimethylpteroylglutamic acid; N10,9-dimethylfolic acid
    Trademarks...
    Literature References: Prepn: Hultquist et al., J. Am. Chem. Soc. 71, 619 (1949); Hultquist, Smith, GB 667098 (1952 to Am. Cyanamid).

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