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Chlophedianol CAS Registry Number: 791-35-5 氯苯达诺

CAS Name: 2-Chloro-a-[2-(dimethylamino)ethyl]-a-phenylbenzenemethanol
Additional Names: 2-chloro-a-(2-dimethylaminoethyl)benzhydrol; 1-o-chlorophenyl-1-phenyl-3-dimethylamino-1-propanol; 1-phenyl-1-(o-chlorophenyl)-3-dimethylaminopropanol; a-(dimethylaminoethyl)-o-chlorobenzhydrol; clofedanol
Trademarks: Tussistop
Percent Composition: C 70.46%, H 6.96%, Cl 12.23%, N 4.83%, O 5.52%

📌 参考资料/链接：
Literature References: Prepn: Henecka, Lorenz, DE 1083277 (1960); Lorenz et al., US 3031377 (1962, both to Bayer).

📄 详细内容

Properties: mp 120°. LD50 i.v. in mice: 70 mg/kg (Lorenz).
Melting point: mp 120°
Toxicity data: LD50 i.v. in mice: 70 mg/kg (Lorenz)
Derivative Type: Hydrochloride
CAS Registry Number: 511-13-7
Trademarks: Coldrin (Nippon Shinyaku); Pectolitan (3M Pharma); Refugal (Bayer); Ulone (3M Pharma); ULO (3M Pharma)
Percent Composition: C 62.58%, H 6.49%, Cl 21.73%, N 4.29%, O 4.90%
Properties: Crystals, mp 190-191°. Freely sol in water, methanol, ethanol. Sparingly sol in ether, benzene, ethyl acetate. LD50 orally in rats: 350 mg/kg; s.c. in mice: 95 mg/kg (Lorenz).
Melting point: mp 190-191°
Toxicity data: LD50 orally in rats: 350 mg/kg; s.c. in mice: 95 mg/kg (Lorenz)
Therap-Cat: Antitussive.
Keywords: Antitussive.
产品链接: 791-35-5››

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