其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Benzoctamine CAS Registry Number: 17243-39-9 苯佐他明

CAS Name: N-Methyl-9,10-ethanoanthracene-9(10H)-methanamine
Additional Names: 1-(methylaminomethyl)dibenzo[b,e]bicyclo[2.2.2]octadiene; 9-(methylaminomethyl)-9,10-dihydro-9,10-ethanoanthracene<...
Literature References: Prepn: BE 610863; P. Schmidt et al., US 3399201 (1962, 1968 to Ciba); Wilhelm, Schmidt, Helv. Chim. Acta 52, 1385 (1969). Pharmacology: Keberle et al., Present Status Psychotropic Drugs (Excerpta Medica, New York, 1969) p 123; Baltzer, Bein, Arch. Int. Pharmacodyn. Ther. 201, 25 (1973). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).

Haloxon CAS Registry Number: 321-55-1

CAS Name: Phosphoric acid bis(2-chloroethyl) 3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
Additional Names: 7-[[bis(2-chloroethoxy)phosphinyl]oxy]-3-chloro-4-methyl-2H-1-benzopyran-2-one;...
Literature References: Prepn: BE 610896 (1962 to Cooper, McDougall Robertson), C.A. 57, 13729g (1962). Toxicity data: Brown et al., Nature 194, 379 (1962).

Clobenzepam CAS Registry Number: 1159-93-9 氯苯西泮

CAS Name: 7-Chloro-10-[2-(dimethylamino)ethyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Additional Names: 7-chloro-10-(2-dimethylaminoethyl)dibenzo[b,e][1,4]diazepin-11(10H)-one; 7-chl...
Literature References: Prepn: BE 611926 (1962 to Parke, Davis), C.A. 57, 13785a (1962); GB 961106; Schmutz, Hunziker, US 3419547 (1964, 1968 both to Wander). Pharmacology: H. Ackermann et al., Med. Exp. 6, 205 (1962); F. Hunziker et al., Arzneim.-Forsch. 13, 324 (1963).

Cloforex CAS Registry Number: 14261-75-7 氯福雷司

CAS Name: [2-(4-Chlorophenyl)-1,1-dimethylethyl]carbamic acid ethyl ester
Additional Names: (p-chloro-a,a-dimethylphenethyl)carbamic acid ethyl ester; ethyl (p-chloro-a,a-dimethylphenethyl)carb...
Literature References: Prepn: BE 619886 (1963 to Troponwerke Dinklage), C.A. 59, 11359c (1963), corresp to GB 970565. Metabolism: Ryrfeldt, Acta Pharmacol. Toxicol. 28, 391 (1970); Buelow et al., Arzneim.-Forsch. 21, 86 (1971).

Paraflutizide CAS Registry Number: 1580-83-2 氟苄氯噻嗪

CAS Name: 6-Chloro-3-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Additional Names: 1,1-dioxo-3-(p-fluorophenylmethyl)-3,4-dihydro-6-chloro-1,2,4-ben...
Literature References: Prepn: BE 620829 (1962 to Lab. Dausse), C.A. 58, 12585g (1963), corresponds to GB 961641; FR M1374 (1962 to Lab. Dausse), C.A. 58, 2462c (1963). Synthesis: J. Klosa, J. Prakt. Chem. 33, 298 (1966).

Anagestone CAS Registry Number: 2740-52-5 阿那孕酮

CAS Name: (6a)-17-Hydroxy-6-methylpregn-4-en-20-one
Additional Names: 6a-methyl-4-pregnen-17a-ol-20-one
Percent Composition: C 79.95%, H 10.37%, O 9.68%
Literature References: Prepn: BE 624370 (1963 to Ortho), C.A. 60, 10764g (1964). GC determn in pharmaceutical tablets: A. P. Shroff, R. E. Huettemann, J. Pharm. Sci. 57, 882 (1968).

Benperidol CAS Registry Number: 2062-84-2 苯哌利多

CAS Name: 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Additional Names: 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-2-benzimidazolinone; 1-[1-[4-(p-f...
Literature References: Prepn: BE 626307 (1963 to Janssen), C.A. 60, 10690c (1964), corresp. to GB 989755.

Nifurprazine CAS Registry Number: 1614-20-6 硝呋拉嗪

CAS Name: 6-[2-(5-Nitro-2-furanyl)ethenyl]-3-pyridazinamine
Additional Names: 3-amino-6-[2-(5-nitro-2-furyl)vinyl]pyridazine; 1-(5-nitro-2-furyl)-2-(6-amino-3-pyridazyl)ethylene; furenapyridazi...
Literature References: Prepn: BE 630163 (1963 to Boehringer, Mann.), C.A. 60, 14516a (1964) corresp to GB 966832.

Rifamide CAS Registry Number: 2750-76-7 利福米特

CAS Name: 4-O-[2-(Diethylamino)-2-oxoethyl]-rifamycin
Additional Names: 2-[(1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,1...
Literature References: Prepn: BE 632770; Sensi, Maggi, US 3313804 (1963, 1967 both to Lepetit); Sensi et al., J. Med. Chem. 7, 596 (1964). Physical and chemical properties: Maggi et al., Farmaco Ed. Prat. 20, 147 (1965). Activity data: Pallanza et al., Arzneim.-Forsch. 15, 800 (1965); Monnier, Bourse, Pathol. Biol. 16, 901 (1968). Metabolic studies: Fürész et al., Arzneim.-Forsch. 15, 802 (1965); Maffii, Shiatti, Toxicol. Appl. Pharmacol. 8, 138 (1966). Toxicology: Dezulian et al., ibid. 126.

Niridazole CAS Registry Number: 61-57-4 尼立达唑

CAS Name: 1-(5-Nitro-2-thiazolyl)-2-imidazolidinone
Additional Names: 1-(5-nitro-2-thiazolyl)-2-oxotetrahydroimidazole; nitrothiamidazolTrademarks: Ambilhar (Novartis)
Percent Composition: C...
Literature References: Prepn: BE 632989 (1963 to Ciba), C.A. 61, 1873d (1964), corresp to GB 986562; Lambert et al., Experientia 20, 452 (1964).