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Clobenzepam CAS Registry Number: 1159-93-9 氯苯西泮

CAS Name: 7-Chloro-10-[2-(dimethylamino)ethyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Additional Names: 7-chloro-10-(2-dimethylaminoethyl)dibenzo[b,e][1,4]diazepin-11(10H)-one; 7-chloro-10-(b-dimethylaminoethyl)-10,11-dihydro-11-oxo-5H-dibenzo[b,e][1,4]diazepine
Percent Composition: C 64.66%, H 5.75%, Cl 11.23%, N 13.31%, O 5.07%

📌 参考资料/链接：
Literature References: Prepn: BE 611926 (1962 to Parke, Davis), C.A. 57, 13785a (1962); GB 961106; Schmutz, Hunziker, US 3419547 (1964, 1968 both to Wander). Pharmacology: H. Ackermann et al., Med. Exp. 6, 205 (1962); F. Hunziker et al., Arzneim.-Forsch. 13, 324 (1963).

📄 详细内容

Properties: Colorless prisms from acetone-ether, mp 165-166°. uv max (alcohol): 230 nm (32,740).
Melting point: mp 165-166°
Absorption maximum: uv max (alcohol): 230 nm (32,740)
Derivative Type: Hydrochloride
CAS Registry Number: 2726-03-6
Trademarks: Tarpan (Wander)
Percent Composition: C 57.96%, H 5.44%, Cl 20.13%, N 11.93%, O 4.54%
Properties: Colorless prisms from alcohol-ether, mp 225-233°. LD50 orally in mice: 330 mg/kg (Hunziker).
Melting point: mp 225-233°
Toxicity data: LD50 orally in mice: 330 mg/kg (Hunziker)
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 1159-93-9››

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