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临床前CDMO研发化合物筛选
Oxytetracycline (Terramycin)
中文名称:土霉素
CAS号:79-57-2
分子式: C22H24N2O9 分子量: 460.43
产品形式: free base
研发状态: Unknown status
研发用途: Acne Vulgaris II or III Degree; Boils
研究机构: Laboratorios Goulart S.A.
研发日期: May-10
研发阶段: Phase 3
Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.
Sertraline HCl
中文名称:盐酸舍曲林
CAS号:79559-97-0
分子式: C17H17Cl2N.HCl 分子量: 342.69
产品形式: HCl
研发状态: Not yet recruiting
研发用途: Opioid Induced Respiratory Depression; Depressive Disorder; Anxiety Disorders
研究机构: Leiden University Medical Center
研发日期: March 15 2023
研发阶段: Phase 1
Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.
Cefixime
中文名称: 头孢克肟
CAS号:79350-37-1
分子式: C16H15N5O7S2 分子量: 453.45
产品形式: free base
研发状态: Recruiting
研发用途: Pediatric Cancer; Solid Tumor
研究机构: Fundació Sant Joan de Déu
研发日期: January 15 2022
研发阶段: Not Applicable
Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
Cyclosporine
中文名称:环孢菌素
CAS号:79217-60-0
分子式: C62H111N11O12 分子量: 1202.61
产品形式: free base
研发状态: Not yet recruiting
研发用途: Hyperglycemia; Renal Transplant Complication Primary Non-Function; Diabetes
研究机构: Rigshospitalet Denmark; Aarhus University Hospital; Odense University Hospital
研发日期: April 1 2024
研发阶段: Phase 4
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
Diammonium Glycyrrhizinate
中文名称: 甘草酸二铵
CAS号:79165-06-3
分子式: C42H62O16.2H3N 分子量: 856.99
产品形式: ammonium salt
研发状态: Recruiting
研发用途: Acute Nasopharyngitis
研究机构: G.ST Antivirals GmbH
研发日期: April 2 2024
研发阶段: Phase 2
Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.
Masitinib (AB1010)
中文名称: 马赛替尼
CAS号:790299-79-5
分子式: C28H30N6OS 分子量: 498.64
产品形式: free base
研发状态: Completed
研发用途: Multiple Myeloma
研究机构: AB Science
研发日期: Feb-05
研发阶段: Phase 2
Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.
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