临床前CDMO研发筛选相关化合物如有产品调研服务, 请致函联系我们
客户展示
临床前CDMO研发化合物筛选
Artesunate (WR-256283)
中文名称:青蒿琥酯; 青蒿脂
CAS号:88495-63-0
分子式: C19H28O8 分子量: 384.42
产品形式: free base
研发状态: Not yet recruiting
研发用途: Severe Malarial Treatment
研究机构: Centre de Recherche Médicale de Lambaréné; Institute of Tropical Medicine University of Tuebingen
研发日期: September 1 2023
研发阶段: Phase 1 : Phase 2
Artesunate (WR-256283) is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.
Anle138b
中文名称:3-(1,3-苯并二恶唑-5-基)-5-(3-溴苯基)-1H-吡唑
CAS号:882697-00-9
分子式: C16H11BrN2O2 分子量: 343.17
产品形式: Free Base
研发状态: Completed
研发用途: Parkinson Disease
研究机构: MODAG GmbH; Aptuit; Quotient Sciences; Nottingham University Hospitals NHS Trust
研发日期: December 22 2020
研发阶段: Phase 1
Anle138b is a novel oligomer modulator and an aggregation inhibitor, blocking the formation of pathological aggregates of prion protein (PrP(Sc)) and of α-synuclein (α-syn) with good oral bioavailability, blood-brain-barrier penetration and no detectable toxicity. Anle138b shows a new approach for disease-modifying therapy in neurodegenerative diseases such as prion and Parkinson's disease.
G-1
中文名称: 1-((3aS,4R,9bR)-4-(6-溴苯并[d][1,3]二氧代l-5-基)-3a,4,5,9b-四氢-3H-环戊并[c]喹啉-8-基)乙酮
CAS号:881639-98-1
分子式: C21H18BrNO3 分子量: 412.28
产品形式: Free base
研发状态: Not yet recruiting
研发用途: Kidney Transplant Patients Eligible for a Solid Biopsy
研究机构: Assistance Publique - Hôpitaux de Paris; CGenetix; Institut National de la Santé Et de la Recherche Médicale France
研发日期: June 10 2024
研发阶段: --
G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30, G protein-coupled estrogen receptor 1, GPER) with Ki of 11 nM.
Amlodipine maleate
中文名称:马来酸氨氯地平
CAS号:88150-47-4
分子式: C24H29ClN2O9 分子量: 524.95
产品形式: Maleate
研发状态: Unknown status
研发用途: Primary Hypertension
研究机构: Peking University First Hospital; Ministry of Science and Technology of the People´s Republic of China; Southern Medical University China; CSPC Ouyi Pharmaceutical Co. Ltd.
研发日期: Feb-13
研发阶段: --
Amlodipine (Amvaz, UK-48340) maleate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
Serdemetan (JNJ-26854165)
中文名称:谢尔德梅坦(JNJ-26854165)
CAS号:881202-45-5
分子式: C21H20N4 分子量: 328.41
产品形式: free base
研发状态: Completed
研发用途: Neoplasms
研究机构: Johnson & Johnson Pharmaceutical Research & Development L.L.C.
研发日期: Nov-06
研发阶段: Phase 1
Serdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.
Vismodegib (GDC-0449)
中文名称:维莫地尼
CAS号:879085-55-9
分子式: C19H14Cl2N2O3S 分子量: 421.30
产品形式: free base
研发状态: Recruiting
研发用途: Basal Cell Carcinoma
研究机构: Stamford Pharmaceuticals Inc.
研发日期: April 9 2024
研发阶段: Phase 2
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
我们的宗旨: 净化, 简洁, 高效Purifying, concise, efficient !我们的口号: 减少中间商赚差价!
即日起可免费注册成为会员, 建立企业产品库, 免费上传产品目录, 企业介绍等. 让你的产品直接呈现给客户.
试运营阶段,所有广告业务5折优惠
分类广告投放
依据化学成分的不同, 针对不同的企业和产品, 我们提供分类产品广告投放.客户展示
优秀企业推荐
