CAS: 881202-45-5; N1-(2-(1H-Indol-3-yl)Ethyl)-N4-(Pyridin-4-yl)Benzene-1,4-Diamine

上下游产品

16H17N3C16H17N3 4-bromopyridine hydr°Chloride

📜N1-(2-(1H-Indol-3-yl)Ethyl)Benzene-1,4-Diamine,4-溴吡啶盐酸盐置于4-溴吡啶盐酸盐体系中,用32的收率获得产物n-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺
参考文献:Inhibitors Of The Interaction Between Mdm2 And P53
标题:Inhibitors Of The Interaction Between Mdm2 And P53
摘要:本发明提供了式(I)的化合物,其用作p53-Mdm2相互作用的抑制剂,以及包含该式(I)的化合物的制药组合物,其中n,M,P,S,T,R1,R2,R3,R4,R5,R6,R7,X,Y,Q和z具有定义的含义.

专利信息

专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.