项目整合精选

聚焦新型临床类新产品的整合与转化. 在创新药研发领域，传统的“单一产品、单打独斗”模式正在被一种更系统化的“项目整合”思维所取代。项目整合的核心，在于将散落在研发早期、中期的创新资产，通过资金、临床资源、产业生态等多维度要素的有机组合，实现从“科学发现”到“临床价值”，再到“商业成功”的跨越。研发与商业的战略整合：从“资产思维”到“组合思维”它要求我们超越单个分子的视野，拥抱一个由技术创新、临床需求、资本支持和商业洞察共同构成的复杂网络。在这个网络中，成功的标准不再是单一的“获批上市”，而是能否通过高效的整合，将科学上的突破，转化为临床上真正可及、商业上可持续、能够惠及患者的解决方案。近年来，药物发现已从传统的小分子化药拓展至更多元的分子类型，这些新型API在项目整合中呈现出独特的开发范式，项目整合的核心挑战在于递送系统的设计与肝外靶向能力的突破。
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

项目整合精选

Sagamacin, Micronomicin sulfate, XK-62-2(free base), KW-1062(free base), Santemycin, Sagamicin

小诺米星Chemical Name: O-2-Amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1--4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1--6)]-2-deoxy-D-streptamine sulfate...
参考文献标题:
文献作者:Matsushima,H.; et al.
参考来源:JP 75126639

Nivadipine, Nilvadipine, CL-287389, SK&F-102362, FK-235, FR-34235, Escor, Nivadil

尼伐地平Chemical Name: 2-Cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 5-isopropyl 3-methyl ester
CAS No. 75530-68-6
项目整合开发状态: Launched-1989
项目研究机构: Fujisawa (Origina...
参考文献标题:1,4-Dihydropyridine derivatives and pharmaceutical method of the same
文献作者:Satu,Y.(Fujisawa Pharmaceutical Co.,Ltd.)
参考来源:BE 0879263; DE 2940833; FR 2438654; GB 2036722; US 4284634; US 4338322

Nicainoprol, RU-42924, CAS-924

尼卡普醇Chemical Name: (?-1,2,3,4-Tetrahydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1-(3-pyridinylcarbonyl)quinoline; (?-1,2,3,4-Tetrahydro-8-[2-hydroxy-3-(isopropylamino)propoxy]-1-nicotinoylquino...
参考文献标题:Nicainoprol
文献作者:Castar,J.; Serradell,M.N.; Hillier,K.
参考来源:Drugs Fut 1984,9(10),749

Nicorandil, RP-46417, SG-75, Adancor, Ikorel, Dancor, Sigmart

尼可地尔 N-(2-羟乙基)-3-吡啶甲酰胺 Chemical Name: N-(beta-Hydroxyethyl)nicotinamide nitrate ester; N-(2-Hydroxyethyl)pyridine-3-carboxamide nitrate ester
CAS No. 65141-46-0, 6265-73-2 (free base)
项目整合开发状态: ...
参考文献标题:SG-75
文献作者:Thorpe,P.J.; Castar,J.
参考来源:Drugs Fut 1979,4(2),134

Nizofenone fumarate, Y-9179, Ekonal

尼唑苯酮Chemical Name: 1-[2-(2-Chlorobenzoyl)-4-nitrophenyl]-2-(diethylaminomethyl)imidazole fumarate; (2-Chlorophenyl)[2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrophenyl]methanone fumarate; 2'-C...
参考文献标题:1-[2-(2-Chlorobenzoyl)-4-nitrophenyl]-2-(diethylaminomethyl)imidazole
文献作者:Nakanishi,M.; et al.(Welfide Corporation)
参考来源:US 3915981

Nizatidine, ZE-101, ZL-101, LY-139037, Zanizal, Nizax, Acinon, Axid

尼扎替丁Chemical Name: N-[2-[2-[(Dimethylamino)methyl]-4-thiazolylmethylthio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
CAS No. 76963-41-2
项目整合开发状态: Launched-1987
项目研究机构: Lilly (Originator), Ital...
参考文献标题:N-Methyl-N'-2-[[(2-dimethylaminomethyl)-4-thiazolyl]methylthio]ethyl-2-nitro-1,1-ethenediamine
文献作者:Pioch,R.P.(Eli Lilly and Company)
参考来源:EP 0049618; GB 2084581; JP 57091980; US 4375547

Nipradolol, Nipradilol, KT-210, K-351, Nipranol, Hypadil

尼普地洛Chemical Name: 3,4-Dihydro-8-(2-hydroxy-3-isopropylaminopropoxy)-3-nitroxy-2H-1-benzopyran; 3,4-Dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2H-1-benzopyran-3-ol 3-nitrate
CAS No. 8148...
参考文献标题:Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds
文献作者:Shiratsuohi,M.; Shimizu,N.; Shigyo,H.; Kyotani,Y.; Kunieda,H.; Kawamura,K.; Sato,S.; Akashi,T.; Nagakura,M.(Kowa Co.,Ltd.)
参考来源:EP 0042299; JP 57007481; JP 82106619

Nileprost, ZK-34798

尼来前列素Chemical Name: (E)-5-Cyano-5-[(1S,5R,6R,7R)-7-hydroxy-6-[(E)-(3S,4RS)-3-hydroxy-4-methyl-1-octenyl]-2-oxabicyclo[3.3.0]octan-3-yliden] pentanoic acid; (5E,9alpha,11alpha,13E,15S)-5-Cyano-6,9-epox...
参考文献标题:5-Cyano-prostacyclin derivs.
文献作者:Vorbr黦gen,H.; Skuballa,W.; Rad點hel,B.; Losert,W.; Loge,P.; M黮ler,B.; Mannesmann,G.(Schering AG)
参考来源:US 4219479

Nisoldipine, Bay-k-5552, Sular, Baymycard, Syscor

尼索地平Chemical Name: (?-2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid methyl 2-methylpropyl diester
CAS No. 63675-72-9
项目整合开发状态: Launched-1990
项目研究机构: Bayer (Originat...
参考文献标题:2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
文献作者:Wehinger,E.; et al.(Bayer AG)
参考来源:US 4154839

Nimesulide, NIM-03, R-805, Nise Gel, Orthobid, Guaxan, Antifloxil, Nimedex, Nisulid, Nimed, Aldoron, Mesulid, Aulin

尼美舒利Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
CAS No. 51803-78-2
项目整合开发状态: Launched-1985
项目研究机构: Boehringer Ingelheim (Originator), Helsinn (Originator), LPB (Originator), ...
参考文献标题:R-805
文献作者:Castar,J.; Chatterjee,S.S.
参考来源:Drugs Fut 1976,1(3),145