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  • 其它产品项目整合
    • 项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
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    其它产品项目整合

  • Picadex CAS Registry Number: 99-00-3 哌嗪荒酸


    CAS Name: 1-Piperazinecarbodithioic acid
    Additional Names: 1-piperazinecarbodithioic acid betaine; 1-piperazinecarbodithioic acid inner salt; piperazine carbon disulfide complex; piperazine dit...
    Literature References: Prepn: Schmidt, Wichmann, Ber. 24, 3237 (1891); Herz, ibid. 30, 1584 (1897). As anthelmintic: Leiper, Watkins, US 2814583 (1957 to Boots Pure Drug).

  • Hexacarbacholine Bromide CAS Registry Number: 306-41-2 溴己氨胆碱


    CAS Name: N,N,N,N',N',N'-Hexamethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diaminium dibromide
    Additional Names: 2,2'-[1,6-hexanediylbis(iminocarbonyloxy)]bis[N,N,N-trimethylethanamini...
    Literature References: Prepn: Schmied et al., AT 185371 (1956); DE 1021842 (1958 to Oesterreichische Stickstoffwerke).

  • Propiomazine CAS Registry Number: 362-29-8 丙酰马嗪


    CAS Name: 1-[10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]-1-propanone
    Additional Names: 10-dimethylaminoisopropyl-2-propionylphenothiazine; propionylpromethazinePercent Composition: C 70...
    Literature References: Prepn: Schmitt et al., Bull. Soc. Chim. Fr. 1957, 1474; Schmitt, FR addn. 71342 (addn. to FR 1176919 to Clin-Byla). Comprehensive description of the hydrochloride: K. B. Crombie, L. F. Cullen, Anal. Profiles Drug Subs. 2, 439-466 (1973). GC determn in plasma and urine: U. Ahs, G. Wickström, J. Chromatogr. 183, 229 (1980). Clinical use as sedative: W. F. Powell et al., Anesth. Analg. 49, 132 (1970); as hypnotic: M. Viukari, P. Miettinen, Neuropsychobiology 12, 134 (1984).

  • Propionylpromazine CAS Registry Number: 3568-24-9 丙酰二甲氨基丙吩噻嗪


    CAS Name: 1-[10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]-1-propanone
    Additional Names: 3-propionyl-10-(g-dimethylaminopropyl)phenothiazine; 10-(3-dimethylaminopropyl)-2-propionylphenoth...
    Literature References: Prepn: Schmitt et al., Bull. Soc. Chim. Fr. 1957, 938, 1474; Schmitt, FR addn. 71342 (1956 to Clin-Byla), C.A. 56, 3486h (1962).

  • Enallylpropymal CAS Registry Number: 1861-21-8 5-烯丙基-5-异丙基-1-甲基巴比妥酸


    CAS Name: 1-Methyl-5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
    Additional Names: 5-allyl-5-isopropyl-1-methylbarbituric acid; N-methyl-5-allyl-5-isopropylbarbituric acid Literature References: Prepn: Schnider, US 2072829 and GB 454779 (1937, 1936, both to Hoffmann-La Roche).

  • Vinyl Acetate CAS Registry Number: 108-05-4 乙酸乙烯酯


    CAS Name: Acetic acid ethenyl ester
    Additional Names: acetic acid vinyl ester
    Percent Composition: C 55.81%, H 7.02%, O 37.17%
    Literature References: Prepn: Schnizer, US 2859241 (1958 to Celanese); Sharp, Steitz, US 2860159 (1958 to Pan Am. Petroleum); Foster, Tobler, J. Am. Chem. Soc. 83, 851 (1961). Toxicity data: Smyth, Carpenter, J. Ind. Hyg. Toxicol. 30, 63 (1948). Study of chronic human exposure: Deese, Joyner, Am. Ind. Hyg. Assoc. J. 30, 449 (1969). Reviews: Leonard "Vinyl Acetate" in Vinyl and Diene Monomers (part 1), E. C. Leonard, Ed. (Wiley-Interscience, New York, 1970) pp 263-328; Faith, Keyes Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds (Wiley-Interscience, New York, 4th ed., 1975) pp 862-867; W. Daniels, "Poly(Vinyl Acetate)" in Kirk-Othmer Encyclopedia of Chemical Technology vol. 23 (Wiley-Interscience, New York, 3rd ed., 1983) pp 817-847. Review of toxicology and human exposure: Toxicological Profile for Vinyl Acetate (PB93-110898, 1992) 166 pp.

  • Homofenazine CAS Registry Number: 3833-99-6 高氟奋乃静


    CAS Name: Hexahydro-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1H-1,4-diazepine-1-ethanol
    Additional Names: 1-(b-hydroxyethyl)-4-[3-(2-trifluoromethylphenothiazin-10-yl)propyl]hexahydr...
    Literature References: Prepn: Schuler et al., US 3040043 (1962 to Degussa).

  • Pipazethate CAS Registry Number: 2167-85-3 匹哌氮酯


    CAS Name: 10H-Pyrido[3,2-b][1,4]benzothiadiazine-10-carboxylic acid 2-(2-piperidinoethoxy)ethyl ester
    Additional Names: 2-(2-piperidinoethoxy)ethyl 10H-pyrido[3,2-b][1,4]benzothiadiazine-10-car...
    Literature References: Prepn: Schuler et al., Ann. 673, 102 (1964); Schuler, US 2989529 (1961 to Degussa).

  • Mepazine CAS Registry Number: 60-89-9 甲哌啶嗪


    CAS Name: 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
    Additional Names: (N-methyl-3-piperidyl)methylphenothiazine; mepasin; pecazine; MPMPTrademarks: Paxital (Warner-Chilcott); Lacumi...
    Literature References: Prepn: Schuler, US 2784185 (1952 to Promonta).

  • Bromosalicylchloranilide CAS Registry Number: 3679-64-9 5-溴-4'-氯水杨酰苯胺


    CAS Name: 5-Bromo-N-(4-chlorophenyl)-2-hydroxybenzamide
    Additional Names: 5-bromo-4'-chlorosalicylanilide; N-5-bromosalicyloyl-p-chloroaniline
    Trademarks: Multifungin (Knoll)
    Percent Comp...
    Literature References: Prepn: Schuler, US 2802029 (1957 to Knoll); Lemaire et al., J. Pharm. Soc. 50, 831 (1961).

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