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临床前CDMO研发化合物筛选
Thymidine (NSC 21548)
中文名称:beta-胸苷
CAS号:50-89-5
分子式: C10H14N2O5 分子量: 242.23
产品形式: free base
研发状态: Not yet recruiting
研发用途: Lynch Syndrome; Recurrent Uterine Corpus Carcinoma; Stage I Uterine Corpus Cancer; Stage II Uterine Corpus Cancer; Stage III Uterine Corpus Cancer; Stage IV Uterine Corpus Cancer
研究机构: Gynecologic Oncology Group; National Cancer Institute (NCI); GOG Foundation
研发日期: Jan-00
研发阶段: --
Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.
Ibudilast
中文名称:异丁司特
CAS号:50847-11-5
分子式: C14H18N2O 分子量: 230.31
产品形式: free base
研发状态: Completed
研发用途: Healthy Volunteers
研究机构: MediciNova
研发日期: June 24 2019
研发阶段: Phase 1
Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities.
O-Acetyl-L-carnitine hydrochloride
中文名称:乙酰-L-肉毒碱盐酸盐
CAS号:5080-50-2
分子式: C9H18ClNO4 分子量: 239.70
产品形式: Salt
研发状态: Recruiting
研发用途: Diabetic Peripheral Neuropathic Pain
研究机构: Haisco Pharmaceutical Group Co. Ltd.
研发日期: May 1 2023
研发阶段: Not Applicable
O-Acetyl-L-carnitine (Acetyl-L-carnitine, O-acetyl-L-carnitine, O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans. It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs.
Aspirin (NSC 27223)
中文名称:阿司匹林
CAS号:50-78-2
分子式: C9H8O4 分子量: 180.16
产品形式: free base
研发状态: Not yet recruiting
研发用途: Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA); Non-radiographic Axial Spondyloarthritis (Nr-axSpA); Axial Psoriatic Arthritis (axPsA); Acute Anterior Uveitis (AAU); Crohn Disease (CD); Ulcerative Colitis (UC); Reactive Arthritis (ReA)
研究机构: Southwest Hospital China
研发日期: Sep-24
研发阶段: --
Aspirin (NSC 27223, Acetylsalicylic acid, ASA) is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin induces autophagy and stimulates mitophagy.
DL-Buthionine-Sulfoximine
中文名称:D,L-蛋氨酸-(S,R)-亚磺酰亚胺
CAS号:5072-26-4
分子式: C8H18N2O3S 分子量: 222.31
产品形式: Free Base
研发状态: Completed
研发用途: Affected and Unaffected Knee in Adoloescent
研究机构: Kuopio University Hospital
研发日期: Jan-98
研发阶段: Not Applicable
DL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine) is an inhibitor of glutathione (GSH) synthesis.
Sorbitol
中文名称:山梨醇
CAS号:50-70-4
分子式: C6H14O6 分子量: 182.17
产品形式: free base
研发状态: Not yet recruiting
研发用途: Charcot-Marie-Tooth Disease (CMT)
研究机构: The Third Xiangya Hospital of Central South University
研发日期: Apr-23
研发阶段: Phase 2
Sorbitol (Glucitol) is a sugar alcohol and a sugar substitute.
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