专利号:US-9433605-B2 优先权日:2006-03-23 标 题 :Method for promoting synthesis of tissue collagen 发明人:KAMIYA TOSHIKAZU; KAMIMURA AYAKO; KAWADA YOKO 权利人:KYOWA HAKKO BIO CO LTD 摘要:An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.
专利号:WO-2009128087-A3 优先权日:2008-04-17 标题:A method for synthesis of dibenzylidene sorbitol in high yields 发明人:GUPTA VIRENDRAKUMAR; SINGH SAURABH; MAKWANA UMESH 权利人:RELIANCE IND LTD; GUPTA VIRENDRAKUMAR; SINGH SAURABH; MAKWANA UMESH 摘要:The invention relates to a method for synthesis of dibenzylidene sorbitol, in high yields, the method comprising heating dimethyl benzaldehyde and D-sorbitol in the presence of a bronsted acid catalyst at a temperature in the range of 50 to 150 degrees wherein the heating is carried out by microwave irradiation. The invention also relates to dibenzyidene sorbitol synthesized by the method and to Clarified polyolefin prepared by using dibenzyidene sorbitol.
专利号:WO-9900440-A1 优先权日:1997-06-26 标 题:Synthesis of a dendritic polyalcohol 发明人:IHRE HENRIK; HULT ANDERS 权利人:PERSTORP AB; IHRE HENRIK; HULT ANDERS 摘要:A process for a double stage convergent synthesis of a polymeric polyalcohol substantially and preferably built up from polyester units and composed of a monomeric or polymeric core to which at least one hyperbranched dendritic branch (dendron) consisting of a number of branching generations is added. The branching generations comprise a polymeric or monomeric branching chain extender having three reactive functions of which two are hydroxyl groups and one is a carboxyl group. The two hydroxyl groups of the branching chain extender is in a first step ketal protected by reacting said two hydroxyl groups with a ketal. A second step includes protection of the carboxyl group of said branching chain extender. The ketal protected branching chain extender and the carboxyl protected chain extender are then employed for repeated addition in a number of step yielding a predetermined number of branching generations. The thus synthesized dendron is finally added to a core having reactive hydroxyl or epoxide groups and the ketal protected hydroxyl groups are optionally deprotected.
专利号:US-2021047609-A1 优先权日:2018-01-26 标 题 :Method For Promoting Synthesis Of Sorbitol Dehydrogenase And Coenzyme Pyrroloquinoline Quinone From Gluconobacter Oxydans 发明人:ZHENG YUGUO; KE XIA; LU YANGHUI; HU ZHONGCE; WU YANG 权利人:UNIV ZHEJIANG TECHNOLOGY; ZHEJIANG MED XINCHANG PHARM 摘要:The present invention discloses a method for promoting the fermentation of Gluconobacter oxydans to produce D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method comprises: Gluconobacter oxydans is inoculated to a fermentation culture medium, fermented and cultured under the conditions of 28-32° C. and 150-180 rpm for 6-24 hours, the fermented solution is centrifuged, and wet bacteria are collected, thus acquiring bacteria cells containing D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method promotes the synthesis of coenzyme pQQ and the enzyme activity of per unit volume D-sorbitol dehydrogenase, Gluconobacter oxydans cultured and acquired using the method is biotransformed to synthesize miglitol precursor 6-deoxy-6-amino(N-hydroxyethyl)-α-L-furan sorbose (6NSL), the conversion progress of the product 6NSL is increased by 21-35%, and a biotransformation step cycle is reduced from 48 hours to 36 hours. In addition, under a same substrate concentration (60 g/L), the cumulative concentration of the product 6NSL is increased by 10 g/L or more.
专利号:US-2015057366-A1 优先权日:2012-03-05 标题 :Synthesis of elemicin and topical analgesic compositions 发明人:LA GRANGE MARTIN JAMES 权利人:LA GRANGE MARTIN JAMES 摘要:The present invention is directed to the synthesis of elemicin and its isomeric form, and their use in topical analgesic formulations, including for dental and veterinary use. Various compositions include gels, films, dressings, cavity filling gels, having analgesic and/or antifungal properties.
专利号:US-6201101-B1 优先权日:1998-11-19 标 题:Catalyst and its use for the synthesis of polyol polyethers 发明人:TOZZOLA GABRIELLA; PO' RICCARDO; CARDI NICOLETTA 权利人:ENICHEM SPA 摘要:The present invention relates to a catalyst having general formula (I):wherein: M represents at least one cation of an element selected from earth-alkaline metals belonging to groups IIA, IIIA, VA, or transition metals belonging to groups IIB, IIIB, VB or VIIIB; n represents an integer between 0 and 2 and x is an integer between 2 and 5.The invention also relates to a process for the synthesis of polyol polyethers which uses a catalyst having general formula (I).
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