CAS: 50847-11-5; 1-(2-Isopropylpyrazolo[1,5-A]Pyridin-3-yl)-2-Methylpropan-1-One

上下游产品

CAS号7583-90-6 1-氨基-2-甲基吡啶碘化物 | CAS号97-72-3 异丁酸酐 | CAS号126959-38-4 2-异丙基吡唑并[1,5-a]... | CAS号101162-39-4 2-(2-hydroxy-1-... | CAS号79-31-2 异丁酸 | CAS号94144-52-2 1-(2-Isopropylp... | CAS号115619-23-3 3-(1-chloro-2-m... | CAS号59942-92-6 2-Isopropylpyra...

1-氨基-2-甲基吡啶碘化物,异丁酸酐置于potassium Carbonate体系中,用 水,乙酸乙酯 作为反应溶剂,化学反应 9.0H,以51.3%的收率获得产物异丁司特
参考文献:Wo2007/146087
标题:Wo2007/146087

专利信息

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:WO-2017072796-A1
优先权日:2015-10-30
标题 :2-pyridone based compounds useful as potential phosphodiesterase3a (pde3a)inhibitors and a process for the preparation thereof
发明人：KUMAR G JAGADEESH; MAHENDAR B; SAIDULU M; BANERJEE S K; RAO V JAYATHIRTHA
权利人:COUNCIL SCIENT IND RES
摘要:Formula A wherein X = COOCH 3 , COOC 2 H 5 , CN Y = Methyl, Phenyl R = alkyl, substituted phenyl, napthyl, furonyl, thiophenyl, substituted quinolinyl The present invention related to compounds of general FormulaA. The invention provides the synthesis of 2-pyridones useful as potential cardio tonic agents and a process for the preparation thereof.

专利号:US-2015283095-A1
优先权日:2012-11-16
标 题:Nanoparticles with biodegradable and biocompatible polymer plga, loaded with the drug for human use pentoxifylline
发明人：CONSTANDIL CÓRDOVA LUIS ERNERTO; IBARRA DURÃ?N PAULA SOLEDAD; VILOS ORTIZ CRISTIAN ANDRES; VELÃ?SQUEZ CUMPLIDO LUIS; PELISSIER SERRANO TERESA; LAURIDO FUENZALIDA CLAUDIO AURELIO; HERNÃ?NDEZ KUNSTMANN ALEJANDRO
权利人:UNIV SANTIAGO CHILE
摘要:The invention relates to a novel pharmaceutical formulation comprising polymer nanoparticles of the biodegradable and biocompatible polymer poly(lactic-glycolic) acid (PLGA), loaded with the drug pentoxifylline, the method for the synthesis of the PLGA nanoparticles loaded with pentoxifylline, and to the use thereof in the effective treatment for the relief of chronic pain and for the prevention of chronic pain via the administration of a single dose.

专利号:WO-2009035652-A1
优先权日:2007-09-13
标 题 :Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof

专利号:US-10335382-B2
优先权日:2013-06-14
标 题:Use of hydrogen sulfide synthesis inhibitors for cancer therapy
发明人：HELLMICH MARK; ZHOU JIA; SZABO CSABA
权利人:HELLMICH MARK; ZHOU JIA; SZABO CSABA; UNIV TEXAS
摘要:In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-β-synthase (CBS) inhibitor, or a hydrogen sulfide neutralizing agent to a patient having a cancer associated with elevated production of hydrogen sulfide.

专利号:US-9751877-B2
优先权日:2012-09-21
标题 :Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; GREEN MICHAEL ERIC; PATEL NANDINI CHATURBHAI; STIFF CORY MICHAEL; TRAN TUAN PHONG; KAUFFMAN GREGORY WAYNE; STEPAN ANTONIA FRIEDERIKE; VERHOEST PATRICK ROBERT
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.