其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Glycolic Acid CAS Registry Number: 79-14-1 羟基乙酸

CAS Name: Hydroxyacetic acid
Additional Names: hydroxyethanoic acid
Percent Composition: C 31.59%, H 5.30%, O 63.11%
Literature References: Constituent of sugar cane juice. Made by the action of NaOH on monochloroacetic acid; also by electrolytic reduction of oxalic acid. Review: Sales brochure on hydroxyacetic acid from E. I. du Pont.

Agaritine CAS Registry Number: 2757-90-6 蘑菇氨酸

CAS Name: L-Glutamic acid 5-[2-[4-(hydroxymethyl)phenyl]hydrazide]
Additional Names: b-N-[g-L(+)-glutamyl]-4-hydroxymethylphenylhydrazine
Percent Composition: C 53.92%, H 6.41%, N 15.72%, O ...
Literature References: Constituent of the commercial, edible mushroom Agaricus bisporus (Lange) Sing. [Psalliota hortensis Cooke var. bispora], Agaricaceae (Agaricales). Isoln and structure: Levenberg, Fed. Proc. 19, 6 (1960); J. Am. Chem. Soc. 83, 503 (1961); Daniels et al., ibid. 3333; see also Levenberg in Methods Enzymol. 17 (Part A), 877 (1970). Synthesis: Kelly et al., J. Org. Chem. 27, 3229 (1962); Hinman, Kelly, US 3274232; US 3288848 (both 1966 to Upjohn).

p, a -Dimethylbenzyl Alcohol CAS Registry Number: 536-50-5 1-(4-甲基苯基)乙醇

CAS Name: a,4-Dimethylbenzenemethanol
Additional Names: p-tolylmethylcarbinol; methyl-p-tolylcarbinol; 4-(a-hydroxyethyl)toluene; 4-methyl-a-phenethyl alcohol; 1-p-tolyl-1-ethanol
Percent Co...
Literature References: Constituent of the essential oil from Curcuma longa L., Zingiberaceae and related plants: Dieterle, Kaiser, Arch. Pharm. 271, 337 (1933). Prepd from p-tolylmagnesium bromide and acetaldehyde in ether: v. Auwers, Kolligs, Ber. 55, 42 (1922); Eisenlohr, Schulz, Ber. 57, 1816 (1924); from 4-methylacetophenone: Gastaldi, Cherchi, Gazz. Chim. Ital. 45, II, 274 (1915).

Octacosanol CAS Registry Number: 557-61-9 1-二十八烷醇

CAS Name: 1-Octacosanol
Additional Names: n-octacosanol; octacosyl alcohol
Percent Composition: C 81.87%, H 14.23%, O 3.90%
Literature References: Constituent of vegetable waxes. Isoln from the wax found on green blades of wheat: Pollard et al., Biochem. J. 27, 1889 (1933); from carnauba wax: Koonce, Brown, Oil Soap (Chicago) 21, 231 (1944). Synthesis starting with behenic acid: Bleyberg, Ulrich, Ber. 64, 2504 (1931); Francis et al., Proc. Roy. Soc. (London) A 158, 691 (1937).

Diphencyprone CAS Registry Number: 886-38-4 二苯基环丙烯酮

CAS Name: 2,3-Diphenyl-2-cyclopropen-1-one
Additional Names: 1,2-diphenylcyclopropenone; DPC
Percent Composition: C 87.35%, H 4.89%, O 7.76%
Literature References: Contact allergen, possibly the smallest neutral aromatic specie. Prepn: R. Breslow et al., J. Am. Chem. Soc. 81, 247 (1959). Crystal structure: H. L. Ammon, ibid. 95, 7093 (1973). Strain energy: A. Greenberg et al., ibid. 105, 6855 (1983). Mechanism of photodissociation: Y. Hirata, N. Mataga, Chem. Phys. Lett. 193, 287 (1992). Report as contact sensitizer: B. M. Hausen, J. Stute, Chem. Ind. 1980, 699. Clinical evaluation in alopecia totalis: B. Monk, Clin. Exp. Dermatol. 14, 154 (1989); of children with alopecia areata: S. MacDonald Hull et al., Br. J. Dermatol. 125, 164 (1991). Review of clinical efficacy: E. Hoting, A. Boehm, ibid. 127, 625-629 (1992).

Benzyl Benzoate CAS Registry Number: 120-51-4 苯甲酸苄酯

CAS Name: Benzoic acid phenylmethyl ester
Additional Names: benzoic acid benzyl ester; benzylbenzenecarboxylate
Trademarks: Acarosan (Allergopharma); Antiscabiosum (Strathmann); Ascabiol (RP...
Literature References: Contained in Peru and Tolu balsams. Prepd by the action of sodium benzylate on benzaldehyde: Kamm, Kamm, Org. Synth. coll. vol. I, 104 (2nd ed., 1941); by the dry esterification of sodium benzoate and benzyl chloride in the presence of triethylamine: Thorp, Nottorf, Ind. Eng. Chem. 39, 1300 (1947). Toxicity studies: Graham, Kuizenga, J. Pharmacol. Exp. Ther. 84, 358 (1945); Draize et al., J. Pharmacol. Exp. Ther. 93, 26 (1948). Comprehensive description: M. M. A. Hassan, J. S. Mossa, Anal. Profiles Drug Subs. 10, 55-74 (1981).

Ferric and Ammonium Acetate Solution CAS Registry Number: 8006-27-7

CAS Name: Basham's mixture
Literature References: Contains 0.16-0.20% Fe and about 3.5% ammonium acetate w/v. Prepn: U.S.D. 25th ed, p 722.

Acriflavine CAS Registry Number: 8048-52-0 吖啶黄素

CAS Name: 3,6-Diamino-10-methylacridinium chloride mixt with 3,6-acridinediamine
Additional Names: neutral acriflavine; euflavine; trypaflavine; neutroflavine; gonacrine
Literature References: Contains 30-40% unmethylated compd. Prepn: L. Benda, Ber. 45, 1787 (1912); M. Gaillot, Q. J. Pharm. Pharmacol. 7, 63 (1934); J. Marshall, ibid. 514. Activity studies: C. H. Browning, W. Gilmour, J. Pathol. Bact. 18, 144 (1913); C. H. Browning et al., Br. Med. J. 1, 73 (1917); H. Berry, Q. J. Pharm. Pharmacol. 14, 149 (1941); H. McIlwain, Biochem. J. 35, 1311 (1941). Toxicology: J. Ungar et al., J. Pharmacol. Exp. Ther. 80, 217 (1944). Reviews: A. Adrien, The Acridines (St. Martin's Press, New York, 2nd ed., 1966); R. M. Acheson, Acridines (Interscience, New York, 2nd ed., 1973).

Ferrous Carbonate Mass CAS Registry Number: 8030-35-1

Additional Names: Blaud's mass; Vallet's mass
Trademarks: Fecarb (Ayerst)
Literature References: Contains 36-41% FeCO3, the remainder consisting of honey and sugar. Prepn: U.S.D. 25th ed., p 575.

Aluminum Boroformate CAS Registry Number: 8011-44-7

Additional Names: Aluminum boro-formicicum
Literature References: Contains about 33% Al2O3, 20% H3BO3, 15% formic acid, 32% H2O. Prepn: Hagers Handb. Pharm. Praxis 1, (Aluminum) p 368 (1930).