其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Betahistine CAS Registry Number: 5638-76-6 倍他司汀

CAS Name: N-Methyl-2-pyridineethanamine
Additional Names: 2-[2-(methylamino)ethyl]pyridine; [2-(2-pyridyl)ethyl]methylamine
Percent Composition: C 70.55%, H 8.88%, N 20.57%
Literature References: Prepn: Löffler, Ber. 37, 161 (1904); Walter et al., J. Am. Chem. Soc. 63, 2771 (1941).

Trimecaine CAS Registry Number: 616-68-2 三甲卡因

CAS Name: 2-Diethylamino-2',4',6'-trimethylacetanilide
Additional Names: N-sym-trimethylphenyldiethylaminoacetamide; 2-diethylaminoacetyl-2',4',6'-trimethylanilideTrademarks: Mesocaine; Mesidic...
Literature References: Prepn: Löfgren, Lundqvist, US 2441498 (1948 to Astra); A. Borovansky et al., J. Am. Pharm. Assoc. 48, 402 (1959).

Chlorphenoxamide CAS Registry Number: 3576-64-5 克立法胺

CAS Name: 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]acetamide
Additional Names: N-(b-hydroxyethyl)-N-[p-(4-nitrophenoxy)benzyl]dichloroacetamide; N-(b-hydroxyethyl)-N-...
Literature References: Prepn: Logemann et al., Farmaco Ed. Sci. 13, 139 (1958); US 2824894 (1958 to Carlo Erba). Antiamebic activity and toxicity data: Carneri, G. Mal. Infett. Parassit. 10, 850 (1958), C.A. 53, 5519C (1959).

Tolcyclamide CAS Registry Number: 664-95-9 格列环脲

CAS Name: N-[(Cyclohexylamino)carbonyl]-4-methylbenzenesulfonamide
Additional Names: 1-cyclohexyl-3-p-tolylsulfonylurea; tolhexamide; glycyclamide; cyclamideTrademarks: Diaboral (Pharmacia)
...
Literature References: Prepn: Logemann, Artini, Ber. 90, 2527 (1957).

Sulfaguanole CAS Registry Number: 27031-08-9 磺胺胍诺

CAS Name: 4-Amino-N-[[(4,5-dimethyl-2-oxazolyl)amino]iminomethyl]benzenesulfonamide
Additional Names: N1-[(4,5-dimethyl-2-oxazolyl)amidino]sulfanilamide; 1-(4,5-dimethyloxazol-2-yl)-3-sulfanily...
Literature References: Prepn: Loop et al., GB 1185139 C.A. 73, 3909w (1970); eidem, US 3562258 (1970, 1971 both to Nordmark-Werke); Loop, Kohlmann, Arzneim.-Forsch. 23, 171 (1973). Toxicology: J. Kuhne et al., ibid. 178. Series of articles on pharmacology: ibid. 172-192.

Sulfamoxole CAS Registry Number: 729-99-7 磺胺二甲唑

CAS Name: 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide
Additional Names: N1-(4,5-dimethyl-2-oxazolyl)sulfanilamide; 2-(p-aminobenzenesulfonamido)-4,5-dimethyloxazole; 4,5-dimethyl-2-su...
Literature References: Prepn: Loop et al., US 2809966 (1957 to Nordmark-Werke). Series of articles on antimicrobial activity, pharmacology and clinical efficacy of mixture with trimethoprim: Arzneim.-Forsch. 26, 595-684 (1976). Toxicity data: F. Lagler et al., ibid. 634.

Sulfamethomidine CAS Registry Number: 3772-76-7 磺胺托嘧啶

CAS Name: 4-Amino-N-(6-methoxy-2-methyl-4-pyrimidinyl)benzenesulfonamide
Additional Names: N1-(6-methoxy-2-methyl-4-pyrimidinyl)sulfanilamide; 2-methyl-4-methoxy-6-sulfanilamidopyrimidine; 4-su...
Literature References: Prepn: Loop, Lührs, Ann. 580, 225 (1953); Loop, DE 926131 (1955 to Nordmark).

Dixanthogen CAS Registry Number: 502-55-6 二黄原酸

CAS Name: Thioperoxydicarbonic acid diethyl ester
Additional Names: dithiobis[thioformic acid] O,O-diethyl ester; O,O-diethyl dithiobis[thioformate]; bisethylxanthogen; diethyl xanthogenate; et...
Literature References: Prepn: Losse, Wottgen, J. Prakt. Chem. 13, 260 (1961). Metabolic studies: Gutenmann, Lisk, J. Agric. Food Chem. 19, 200 (1971). Toxicity: G. W. Bailey, J. L. White, Residue Rev. 10, 97 (1965).

Terbacil CAS Registry Number: 5902-51-2 甲醇中特草定

CAS Name: 5-Chloro-3-(1,1-dimethylethyl)-6-methyl-2,4(1H,3H)-pyrimidinedione
Additional Names: 3-tert-butyl-5-chloro-6-methyluracilTrademarks: Sinbar (DuPont)
Percent Composition: C 49.89%, ...
Literature References: Prepn: Loux, US 3235357 (1966 to du Pont). Herbicidal activity and physical properties: G. D. Hill, Jr. et al., 2nd Symp. New Herbic. 1965, 313, C.A. 66, 18234b (1967). Metabolism and mode of action: Herholdt, Diss. Abstr. Int. B 30, 1978 (1969).

Hexestrol Bis( b -diethylaminoethyl ether) CAS Registry Number: 2691-45-4 2,2'-[(1,2-二乙基乙基)双(p-苯氧)]双(tri乙基)胺

CAS Name: 2,2'-[(1,2-Diethyl-1,2-ethanediyl)bis(4,1-phenyleneoxy)]bis[N,N-diethylethanamine]
Additional Names: 2,2'''-[(1,2-diethylethylene)bis(p-phenyleneoxy)]bis(triethylamine); 4,4'-bis(b-di...
Literature References: Prepn: Lowe et al., J. Chem. Soc. 1951, 3286.