其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Succinanilic Acid CAS Registry Number: 102-14-7 4-氧代-4-(苯氨基)丁酸

CAS Name: 4-Oxo-4-(phenylamino)butanoic acid
Additional Names: succinic acid monoanilide; N-phenylsuccinamic acid; N-phenylbutanedioic acid monoamide
Percent Composition: C 62.17%, H 5.74%, ...
Literature References: Prepd by boiling succinic anhydride with aniline in benzene: Menschutkin, Ann. 162, 176 (1872); Warren, Briggs, Ber. 64, 29 (1931); L. F. Fieser, Experiments in Organic Chemistry (Boston, 3rd ed., 1955) p 105.

a , a¢ -Dibromo-d-camphor CAS Registry Number: 514-12-5 3,3-二溴-1,7,7-三甲基双环[2.2.1]庚烷-2-酮

CAS Name: d-3,3-Dibromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
Additional Names: d-3,3-dibromo-2-bornanone; dibromated camphor
Percent Composition: C 38.74%, H 4.55%, Br 51.55%, O 5.16%
Literature References: Prepd by brominating a-bromocamphor: Lowry, J. Chem. Soc. 73, 569 (1898). Conformation: Brutcher et al., J. Am. Chem. Soc. 81, 4915 (1959). Review: J. L. Simonsen, L. N. Owen, The Terpenes vol. 2 (Cambridge University Press, London, 2nd ed., 1949) pp 401, 405.

Tropylium Bromide CAS Registry Number: 5376-03-4

CAS Name: Cycloheptatrienylium bromide
Additional Names: cycloheptatrienocarbonium bromide
Percent Composition: C 49.16%, H 4.13%, Br 46.72%
Literature References: Prepd by bromination of 1,3,5-cycloheptatriene in carbon tetrachloride, followed by removal of the CCl4 and heating the residue in vacuo for several days: von Doering, Knox, J. Am. Chem. Soc. 79, 352 (1957); King, Stone, Inorg. Synth. 7, 99 (1963).

p-Bromoacetanilide CAS Registry Number: 103-88-8 4'-溴乙酰苯胺

CAS Name: N-(4-Bromophenyl)acetamide
Additional Names: 4'-bromoacetanilide; monobromoacetanilide; bromoanilide
Trademarks: Antisepsin; Asepsin; Bromoantifebrin
Percent Composition: C 44.8...
Literature References: Prepd by bromination of acetanilide: Remmers, Ber. 7, 346 (1874); Merker, Vona, J. Chem. Educ. 26, 613 (1949); Knowles, Alt, US 3012035 (1959 to Monsanto).

Dibromogallic Acid CAS Registry Number: 602-92-6 二溴五倍子酸

CAS Name: 2,6-Dibromo-3,4,5-trihydroxybenzoic acid
Additional Names: 2,6-dibromogallic acid; gallobromol
Percent Composition: C 25.64%, H 1.23%, Br 48.74%, O 24.40%
Literature References: Prepd by bromination of gallic acid: Etti, Ber. 11, 1879 (1878).

a -Bromoisobutyric Acid CAS Registry Number: 2052-01-9 2-溴代异丁酸

CAS Name: 2-Bromo-2-methylpropanoic acid
Percent Composition: C 28.77%, H 4.22%, Br 47.85%, O 19.16%
Literature References: Prepd by bromination of isobutyric acid: Markownikow, Ann. 153, 228 (1870); Smissman, J. Am. Chem. Soc. 76, 5805 (1954).

Bromolysergide CAS Registry Number: 478-84-2 2-溴麦角酸二乙基酰胺

CAS Name: (8b)-2-Bromo-9,10-didehydro-N,N-diethyl-6-methylergoline-8-carboxamide
Additional Names: D-2-bromolysergic acid diethylamide; 2-bromo-N,N-diethyl-D-lysergamide; bromo-LSDPercent Compo...
Literature References: Prepd by bromination of lysergide, q.v.: Troxler, Hofmann, Helv. Chim. Acta 40, 2160 (1957). Serotonin antagonist without the hallucinogenic activity of LSD: J. P. Bennett, S. H. Snyder, Brain Res. 94, 523 (1975).

d-Camphocarboxylic Acid CAS Registry Number: 18530-30-8 (+)-樟脑羧酸

CAS Name: 4,7,7-Trimethyl-3-oxobicyclo[2.2.1]heptane-2-carboxylic acid
Additional Names: d-2-oxo-3-bornanecarboxylic acid; d-3-camphorcarboxylic acid; d-2-oxo-3-camphanecarboxylic acid; d-3-car...
Literature References: Prepd by carboxylation of d-camphor: Brühl, Ber. 24, 3373 (1891).

Nicotinyl Alcohol CAS Registry Number: 100-55-0 3-吡啶甲醇

CAS Name: 3-Pyridinemethanol
Additional Names: b-pyridylcarbinol; 3-hydroxymethylpyridine; nicotinic alcoholTrademarks: Roniacol (Roche); Ronicol
Percent Composition: C 66.04%, H 6.47%, N 12...
Literature References: Prepd by catalytic hydrogenation of 3-pyridinecarboxaldehyde: Panizzon, Helv. Chim. Acta 24, supplemental issue in honor of Gadient Engi, p 26E (1941); by lithium aluminum hydride reduction of ethyl nicotinate: Rosenmund, Zymalkowski, Ber. 85, 156 (1952); Cohen, US 2520037 (1950); Mosher, Tessieri, J. Am. Chem. Soc. 73, 4926 (1951); of methyl nicotinate: Bohlmann, Ber. 86, 1423 (1953). From 3-cyanopyridine: Chase, US 2615896 (1952 to Hoffmann-La Roche); from 3-aminomethylpyridine: Schläpfer, US 2547048 (1951 to Hoffmann-La Roche); from thionicotinic acid S-methyl ester: Ruzicka, Prelog, US 2509171 (1950 to Ciba).

p-Aminoacetanilide CAS Registry Number: 122-80-5 对氨基乙酰苯胺

CAS Name: N-(4-Aminophenyl)acetamide
Additional Names: 4'-aminoacetanilide; acetyl-p-phenylenediamine
Percent Composition: C 63.98%, H 6.71%, N 18.65%, O 10.65%
Literature References: Prepd by catalytic hydrogenation of 4¢-nitroacetanilide: Atkinson et al., J. Chem. Soc. 1954, 2023. Crystal and molecular structure: M. Haisa et al., Acta Crystallogr. 33B, 2449 (1977).