其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Monacetin CAS Registry Number: 26446-35-5 甘油单乙酸酯

CAS Name: 1,2,3-Propanetriol monoacetate
Additional Names: acetin; monoacetin; glyceryl monoacetate
Percent Composition: C 44.77%, H 7.51%, O 47.71%
Literature References: Obtained along with the di- and triacetates by heating glycerol with glacial acetic acid.

Triclobisonium Chloride CAS Registry Number: 79-90-3 曲比氯铵

CAS Name: N,N,N',N'-Tetramethyl-N,N'-bis[1-methyl-3-(2,2,6-trimethylcyclohexyl)propyl]-1,6-hexanediaminium dichloride
Additional Names: hexamethylenebis[dimethyl[1-methyl-3-(2,2,6-trimethylcycl...
Literature References: Obtained as the hemihydrate. Prepn: Goldberg, Teitel, US 3064052 (1962 to Hoffmann-La Roche). Clinical application: Edelson et al., Antibiot. Annu. 1958-1959, 110; Robinson, Harmon, ibid. 113. Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 507-521 (1973).

Scillabiose CAS Registry Number: 40525-07-3 海葱二糖

CAS Name: 6-Deoxy-4-O-b-D-glucopyranosyl-L-mannose
Additional Names: 4-O-D-glucopyranosyl-L-rhamnose; glucosidorhamnose
Percent Composition: C 44.17%, H 6.80%, O 49.03%
Literature References: Obtained by acid hydrolysis of scillaren A: Stoll et al., Helv. Chim. Acta 16, 703 (1933); Zemplén, C.A. 33, 4202 (1939); from glucoscilliphäosid: Stoll et al., Helv. Chim. Acta 35, 2495 (1952). Structure: Stoll, Renz, Enzymologia 7, 362 (1939), C.A. 34, 62983 (1940).

Protoverine CAS Registry Number: 76-45-9

CAS Name: (3b,4a,6a,7a,15a,16b)-4,9-Epoxycevane-3,4,6,7,14,15,16,20-octol
Percent Composition: C 61.70%, H 8.25%, N 2.66%, O 27.39%
Literature References: Obtained by alkaline hydrolysis of protoveratrine A: Poethke, Arch. Pharm. 275, 571 (1937); Stoll, Seebeck, Helv. Chim. Acta 36, 718 (1953). Structure: Kupchan et al., Chem. Ind. (London) 1958, 1626; J. Am. Chem. Soc. 81, 1009 (1959); 82, 2242 (1960). Comparative toxicity: O. Krayer et al., J. Pharmacol. Exp. Ther. 82, 167 (1944); K. Tanaka, ibid. 113, 89 (1955).

Gallic Acid CAS Registry Number: 149-91-7 没食子酸; 3,4,5-三羟基苯甲酸

CAS Name: 3,4,5-Trihydroxybenzoic acid
Percent Composition: C 49.42%, H 3.55%, O 47.02%
Literature References: Obtained by alkaline or acid hydrolysis of the tannins from nutgalls; also by enzymatic hydrolysis using spent broths from Penicillium glaucum or Aspergillus niger which contain tannase: A. G. Perkin, O. Gunnell, J. Chem. Soc. 69, 1303 (1896); Hsias, Huang Hai No. 7, 51 (1946), C.A. 42, 3901i (1948); Cochrane, Econ. Bot. 2, 145 (1948); Toth, Henster, Acta Chim. Acad. Sci. Hung. 2, 209 (1952). Prepn from tannin containing materials: Krueger et al., US 2723992 (1955 to Mallinckrodt). Synthesis from aliphatic materials: Shipchandler et al., J. Chem. Soc. Perkin Trans. 1 1975, 1400. Biosynthesis: Haslam et al., J. Chem. Soc. 1961, 1854. Study of polymorphic forms: E. Lindpainter, Mikrochemie 27, 21 (1939). Toxicity studies: J. W. Dollahite et al., Am. J. Vet. Res. 23, 1264 (1962).

Reserpic Acid CAS Registry Number: 83-60-3 利舍平酸

CAS Name: (3b,16b,17a,18b,20a)-18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid
Additional Names: reserpinolic acid
Percent Composition: C 65.98%, H 7.05%, N 7.00%, O 19.98%
Literature References: Obtained by controlled alkaline hydrolysis of reserpine: Dorfman et al., Helv. Chim. Acta 37, 59 (1954); Schlittler, US 2824874 (1958).

Isobutyl Iodide CAS Registry Number: 513-38-2 碘代异丁烷

CAS Name: 1-Iodo-2-methylpropane
Percent Composition: C 26.11%, H 4.93%, I 68.96%
Literature References: Obtained by distilling isobutyl alcohol and HI, or from isobutyl alcohol, iodine and phosphorus.

Isobutyl Thiocyanate CAS Registry Number: 591-84-4 2-甲基丙酯硫氰酸酯

Additional Names: Isobutyl sulfocyanate
Percent Composition: C 52.13%, H 7.87%, N 12.16%, S 27.83%
Literature References: Obtained by distilling potassium isobutyl sulfate with NaCSN.

Sodium Metaborate CAS Registry Number: 7775-19-1 偏硼酸钠

Percent Composition: B 16.43%, Na 34.94%, O 48.63%
Literature References: Obtained by fusing equivalent mol wts of borax and sodium carbonate.

Penicillin S CAS Registry Number: 575-54-2

CAS Name: (2S,5R,6R)-6-[[[(3-Chloro-2-butenyl)thio]acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Additional Names: g-chlorocrotylmercaptomethylpenicillin<...
Literature References: Obtained by growing a penicillin-producing mold in a culture medium contg g-chlorocrotylmercaptoacetic acid: Ford et al., J. Am. Chem. Soc. 70, 3522 (1948); Ford et al., Antibiot. Chemother. 3, 1149 (1953).