合成工艺路线中心备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目整合推广和市场调研服务, 请致函联系我们
数据库发展方向
1. 智能化融合：发展数据挖掘、集成、分析、可视化及人工智能工具，实现数据与文献、模型、计算等资源的有机融合，促进领域数智驱动科研新范式变革.
2. 标准化体系建设：以统一的数据标准管理体系为基础，系统整合全链条多源异构数据，聚焦高价值业务需求，精准构建结构合理、标注规范、语义清晰的数据资源.
3. 开放共享生态：开展数据提供方、使用方和服务方生态体系建设，实现多元主体间数据共享、共用、共治。.
4. 多模态数据处理：构建“全模态数据治理平台+高质量数据服务”一体化解决方案，提升非结构化数据处理能力.
客户展示
合成工艺路线中心
Atomoxetine CAS# 83015-26-3 托莫西汀
Atomoxetine is a selective inhibitor of noradrenaline reuptake; atomoxetine was originally called tomoxetine but changed to avoid any potential confusion with tamoxifen that might lead to errors in di...
Wickens, Zachary K.; Skakuj, Kacper; Morandi, Bill; Grubbs, Robert H. Catalyst-Controlled Wacker-Type Oxidation: Facile Access to Functionalized Aldehydes. Journal of the American Chemical Society. Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering. California Institute of Technology. Pasadena, USA 91125. Volume 136. Issue 3. Pages 890-893. 2014
Elagolix sodium CAS# 832720-36-2 恶拉戈利钠
Elagolix, also known as NBI56418 and ABT-620, is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultima...
Reference: Chen, Chen; Wu, Dongpei; Guo, Zhiqiang; Xie, Qiu; Reinhart, Greg J.; Madan, Ajay; Wen, Jenny; Chen, Takung; Huang, Charles Q.; Chen, Mi; Chen, Yongsheng; Tucci, Fabio C.; Rowbottom, Martin; Pontillo, Joseph; Zhu, Yun-Fei; Wade, Warren; Saunders, John; Bozigian, Haig; Struthers, R. Scott. Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Journal of Medicinal Chemistry. Volume 51. Issue 23. Pages 7478-7485. Journal. (2008).
Gepirone CAS# 83928-76-1 吉哌隆
Gepirone is a selective 5-HT(1A) agonist that significantly reduces depression. Gepirone is a drug of the azapirone group which is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone...
Improved synthesis method for gepironeBy: Ye, Guangming; et alDier Junyi Daxue Xuebao (2005), 26(2), 223-224
Canagliflozin CAS# 842133-18-0 卡格列净
Canagliflozin (INN, trade name Invokana) is a drug for the treatment of type 2 diabetes. It was developed by Mitsubishi Tanabe Pharma and is marketed under license by Janssen, a division of Johnson & ...
Nomura, Sumihiro; Sakamaki, Shigeki; Hongu, Mitsuya; Kawanishi, Eiji; Koga, Yuichi; Sakamoto, Toshiaki; Yamamoto, Yasuo; Ueta, Kiichiro; Kimata, Hirotaka; Nakayama, Keiko; Tsuda-Tsukimoto, Minoru. Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Co-transporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus. Journal of Medicinal Chemistry. Volume 53. Issue 17. Pages 6355-6360. Journal. (2010).
Bedaquiline CAS# 843663-66-1 贝达喹啉
Bedaquiline, also known as TMC207 and R207910, is a diarylquinoline anti-tuberculosis drug, which was discovered by a team led by Koen Andries at Janssen Pharmaceutica. Bedaquiline blocks the proton p...
Saga, Yutaka; Motoki, Rie; Makino, Sae; Shimizu, Yohei; Kanai, Motomu; Shibasaki, Masakatsu. Catalytic Asymmetric Synthesis of R207910. Journal of the American Chemical Society. Volume 132. Issue 23. Pages 7905-7907. Journal. (2010).
Cabozantinib CAS# 849217-68-1 卡博替尼
Cabozantinib, also known as XL-184 or BMS-907351, is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds...
Laus, Gerhard; Schreiner, Erwin; Nerdinger, Sven; Kahlenberg, Volker; Wurst, Klaus; Vergeiner, Stefan; Schottenberger, Herwig. Crystal structures of intermediates in a new synthesis of antitumor drug cabozantinib. Heterocycles. Volume 93. Issue 1, Spec. Issue. Pages 323-332. Journal; Online Computer File. (2016).
Afatinib CAS# 850140-72-6 阿法蒂尼(BIBW2992)
Afatinib, also know as BIBW 2992, is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. EGFR/HER2 tyrosine kinase inhibitor BIBW 2992 irrevers...
Kovacevic, Tatjana; Mesic, Milan; Avdagic, Amir; Zegarac, Miroslav. An alternative synthesis of the non-small cell lung carcinoma drug afatinib. Tetrahedron Letters. Volume 59. Issue 47. Pages 4180-4182. Journal; Online Computer File. (2018).
Alogliptin CAS# 850649-61-5 阿格列汀
Alogliptin is a DPP-4 inhibitor used for the treatment of Type 2 diabetes. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypog...
Ji, Jianjian; Chen, Caiyou; Cai, Jiayu; Wang, Xinrui; Zhang, Kai; Shi, Liyang; Lv, Hui; Zhang, Xumu. Highly enantioselective synthesis of non-natural aliphatic α-amino acids via asymmetric hydrogenation. Organic & Biomolecular Chemistry. Volume 13. Issue 28. Pages 7624-7627. Journal; Online Computer File. (2015).
Seladelpar CAS# 851528-79-5 司拉德帕
Seladelpar is a highly selective agonist of the peroxisome proliferator-activated receptor delta (PPARδ) (human PPARδ EC₅₀ ≈ 2 nM; >750-fold and >2,500-fold selectivity vs PPARα/γ) in cell assays. In...
Patent#: WO2005042478
Samidorphan CAS# 852626-89-2
Samidorphan, also known as ALKS-33 and RDC-0313, is an opioid modulator. In preclinical studies, Samidorphan demonstrated potent and selective antagonism at the μ-opioid receptor (MOR) with a reporte...
Patent#: WO2012005795
我们的宗旨: 净化, 简洁, 高效Purifying, concise, efficient !我们的口号: 减少中间商赚差价!
即日起可免费注册成为会员, 建立企业产品库, 免费上传产品目录, 企业介绍等. 让你的产品直接呈现给客户.
试运营阶段,所有广告业务5折优惠
分类广告投放
依据化学成分的不同, 针对不同的企业和产品, 我们提供分类产品广告投放.客户展示
优秀企业推荐
