CAS: 20427-56-9; Tetraoxoruthenium

该化合物是一种挥发性,高度氧化的化合物,主要用于专门的化学合成和催化用途,其强烈的氧化性特性使其在有机转化中具有价值,特别是对于碳-碳双环或氧化酒精到碳基化合物中的价值. RuO4还用于电子材料的薄膜沉降,因为它在减少时能够形成二氧化亚球(RuO2),处理需要严格的预防措施,因为其毒性和浓度形式的爆炸性.关键优势包括其高度的再活动性,氧化反应中的选择性和先进材料科学的实用性. 它通常在原地产生或用作受控应用的稀释溶液.

结构式图片

欧盟法规

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上下游产品

CAS号7440-18-8 钌 | CAS号7722-64-7 高锰酸钾 | CAS号14380-61-1 hyp°Chlorite | CAS号14521-18-7 Ruthenium fluoride | CAS号25604-36-8 trans-tetraammi... | CAS号67251-55-2 monoruthenium(V... | CAS号80937-33-3 oxygen | CAS号7440-18-8 钌 | CAS号14014-88-1 溴化钌(III)水合物 | CAS号10049-08-8 三氯化钌 | CAS号13896-65-6 无水化钌(III)碘

合成工艺路线路线简述

  • 合成目标产物 Ruthenium Tetroxide 主要起始原料 Ruthenium
  • (文献来源)合成步骤主要原料 Ruthenium
📜Ruthenium(Iv) Oxide 以 Not Given 用作溶剂,化学反应生成四氧化钌
参考文献:Baranaev,M. K.; Vereskunnov,V. G.; Zakharova,K. P.,Atomnaya Energiya,1964,Vol. 17,P. 502-503
标题:Baranaev,M. K.; Vereskunnov,V. G.; Zakharova,K. P.,Atomnaya Energiya,1964,Vol. 17,P. 502-503

专利信息


专利号:EP-4092127-A1
优先权日:2021-05-18
标题:Enzyme-catalytic method for the direct stereoselective synthesis of gamma-(acyloxy) carboxylic acids
发明人:PARVE JAAN; KUDRJASHOVA MARINA; GATHERGOOD NICHOLAS; PARVE OMAR
权利人:TALLINN UNIV OF TECHNOLOGY
摘要:The present invention is a method for the stereoselective straightforward synthesis of gamma-acyloxy carboxylic acids of novel structure starting from racemic gamma-hydroxy carboxylic acid salts that are obtained by alkaline hydrolysis of the racemic gamma-lactones. The salt is acylated by enzyme catalysis in an organic solvent containing an acyl donor and an immobilised lipase, on stirring at room temperature (ca 20 °C) until reaching the conversion rate required. After that, the reaction mixture is acidified and extracted and the product treated with catalytic amount of para-toluenesulfonic acid in toluene during the time required for the relactonisation of the unreacted salt enantiomer. Thereafter, the target gamma-acyloxy carboxylic acid formed from one enantiomer of the starting compound and relactonised gamma-lactone formed from the other, unreacted enantiomer of the starting compound are isolated using a routine separation method, such as distillation, extraction with NaHCO3 water solution followed by acidification or column chromatography.

专利号:US-12281135-B2
优先权日:2019-07-25
标 题 :Synthesis of 6-azido-6-deoxy-2-n-acetyl-hexosamine-nucleoside diphosphate
发明人:HOOGENBOOM JORIN; WIJDEVEN MARIA ANTONIA; VERKADE JORGE MERIJN MATHIEU; VAN DELFT FLORIS LOUIS; VAN BERKEL SANDER SEBASTIAAN
权利人:SYNAFFIX BV
摘要:The current invention concerns methods for the synthesis of 6-azido-6-deoxy-2-N-acetyl-monosaccharide-nucleoside diphosphate, in particular 6-azido-6-deoxy-2-N-acetyl-D-galactosamine-nucleoside diphosphate or 6-azido-6-deoxy-2-N-acetyl-D-glucosamine-nucleoside diphosphate. The synthesis method according to the invention is characterized by being highly efficient and high yielding. Also part of the present invention are key intermediates of this process.

专利号:US-2023183177-A1
优先权日:2020-04-24
标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
发明人:GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
权利人:PHARMAZELL GMBH
摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.

专利号:WO-2023039068-A1
优先权日:2021-09-08
标题:Compositions and methods for synthesis of peptide nucleic acid intermediates
发明人:COULL JAMES M; GILDEA BRIAN D
权利人:NEUBASE THERAPEUTICS INC
摘要:The present disclosure provides intermediates for the synthesis of peptide nucleic acid (PNA) backbones and monomers, such as cyclic intermediates, and methods of making the same.

专利号:US-12018313-B2
优先权日:2016-12-28
标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles
发明人:EMBREE MALLORY
权利人:NATIVE MICROBIALS INC
摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.

专利号:US-9856251-B2
优先权日:2008-09-03
标题:Substituted berbines and processes for their synthesis
发明人:WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides processes for the synthesis of substituted berbine compounds. Also provided are intermediates used in the synthesis of substituted berbine compounds.

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合成参考文献


参考文献:10.3390/molecules19056534
摘要:Piccialli V. Ruthenium tetroxide and perruthenate chemistry. Recent advances and related transformations mediated by other transition metal oxo-species. Molecules. 2014 May 21;19(5):6534–82.
参考文献:10.1186/s40824-021-00226-6
摘要:Jeong WY, Kwon M, Choi HE, Kim KS. Recent advances in transdermal drug delivery systems: a review. Biomaterials Research. 2021 Jul 28;25(1):24. doi: 10.1186/s40824-021-00226-6.
摘要:Swartzendruber DC. Studies of epidermal lipids using electron microscopy. Semin Dermatol. 1992 Jun;11(2):157–61.
参考文献:10.1159/000211287
摘要:Menon GK, Bommannan DB, Elias PM. High-frequency sonophoresis: permeation pathways and structural basis for enhanced permeability. Skin Pharmacol. 1994;7(3):130–9. doi: 10.1159/000211287.
参考文献:10.1007/bf00179344
摘要:Curley RW, Panigot MJ, Hansen AP, Fesik SW. Stereospecific assignments of glycine in proteins by stereospecific deuteration and 15N labeling. Journal of Biomolecular NMR. 1994 May;4(3):335–40. doi: 10.1007/bf00179344.
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