CAS: 507-16-4; Thionyl Bromide

该化合物是一种化学化合物,其特点是用作有机合成的试剂,特别是用于将酒精转化为溴化物;是一种无色的,无黄色的液体,其气味很浓,众所周知,它具有反应性,能够在水解过程中释放有毒气体;硫基溴是一种极分子,它有助于有机溶剂中的溶解性;它有一个相对较低的沸点,它具有挥发性,需要小心处理;该化合物通常储存在密封的容器中,以防止吸收水分,因为它与水发生强烈反应,生产二氧化硫和氢溴;在安全方面,硫基溴被归类为危险,在处理时必须使用适当的个人防护设备;其应用范围超出有机合成,将它用于其他含溴化合物的准备,在化学反应中展示其多功能.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

sulfur dioxide potassium bromide thionyl chloride boron tribromide1-Bromomethyl-4-(2-chloro-ethoxy)-benzene 2-(3-benzylbenzyloxy)ethanol hydrogen sulfide sulfur dioxide

合成工艺路线路线简述

  • 合成目标产物 Thionyl Bromide 主要起始原料 Sulfur Dioxide And Phosphorus Pentabromide
  • (文献来源)合成步骤主要原料 Sulfur Dioxide 和 Phosphorus Pentabromide
📜氢溴酸置于氯化亚砜体系中,化学反应生成 二溴亚砜
参考文献:Besson,A.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1896,Vol. 122,P. 815-820
标题:Besson,A.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1896,Vol. 122,P. 815-820

专利信息


专利号:US-2008032964-A1
优先权日:2006-04-10
标题:Process for the synthesis of azetidinone
发明人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

专利号:US-4910310-A
优先权日:1988-10-03
标 题:Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives
发明人:CAMPBELL ARTHUR L; BEHLING JAMES R; BABIAK KEVIN A; NG JOHN S; MUELLER RICHARD A; FLEET GEORGE W J
权利人:SEARLE & CO
摘要:Novel intermediates and method for the chemical synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives are provided. A preferred intermediate is 1,5-dideoxy-1,5-imino-3, 4-O-isopropylidene-L-fucitol which is used to prepare the HIV inhibitor 1,5-dideoxy-1,5-imino-[N-ω-methyl caproate]-L-fucitol. These compounds are prepared in a short synthesis from the known compound 2,3-O-isopropylidene-D-lyxono-1,4-lactone or in a multi-step synthesis from D-galactose.

专利号:US-7355036-B2
优先权日:2001-07-03
标 题 :Two-stage protective groups for the synthesis of biopolymers
发明人:GUEIMIL RAMON; SCHEFFLER MATTHIAS; STAEHLER PEER F; BEIJER BARBRO
权利人:FEBIT AG
摘要:The invention relates to a method for the synthesis of a nucleic acid by gradual breakdown from protected synthesis building blocks carrying two-stage protective groups. The two-stage protective groups are split by means of a first exposure step and a subsequent chemical treatment step

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:US-4598160-A
优先权日:1983-07-15
标题 :Intermediate phenolic compounds for the catalytic synthesis of chromans
发明人:TRUESDALE LARRY K
权利人:HOFFMANN LA ROCHE
摘要:A catalytic synthesis of chromans in racemic or optically active forms, including intermediates thereto; the synthesis employs an asymmetric palladium (II) catalyzed oxidative cyclization of a 2-homoallylphenol and provides intermediates useful in making chromans, especially vitamin E in racemic or optically active forms.

专利号:US-3978084-A
优先权日:1973-12-03
标题 :Synthesis of biotin
发明人:CONFALONE PASQUALE NICHOLAS; USKOKOVIC MILAN RADOJE; PIZZOLATO GIACOMO
权利人:HOFFMANN LA ROCHE
摘要:Synthesis of biotin from 4-carbomethoxy-2-(4,5-dihydrothiophen-3(2H)-one)-valeric acid methyl ester, and thiophene intermediates in this synthesis.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Ouyang, Y.; Shou, J.-Y.; Qing, F.-L., Science of Synthesis: Special Topics, (2022) 1, 260.
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