CAS: 556-33-2; H-Gly-Gly-Gly-Oh

相似化合物

28320-73-2 170941-79-4 2566-20-3

上下游产品

CAS号75719-94-7 (2S,3R,4S,5S,6R... | CAS号2566-20-3 N-苄氧羰基-L-亮氨酰甘氨酰甘氨酸 | CAS号56-40-6 甘氨酸 | CAS号15474-96-1 氯乙酰基甘氨酰甘氨酸 | CAS号27440-17-1 N-carboxy-glycy... | CAS号28320-73-2 N-[N-[N-[叔丁氧羰基]... | CAS号29022-11-5 Fm°C-甘氨酸 | CAS号637-84-3 四聚甘氨酸 | CAS号31384-90-4 血管紧张素转化酶底物 | CAS号1145-32-0 苯甲酰甘氨酰基氨基乙酸 | CAS号471-46-5 草酰二胺 | CAS号20228-72-2 Z-Gly-Gly-Gly-G... | CAS号106-57-0 甘氨酸酐 | CAS号556-50-3 双甘肽 | CAS号56-40-6 甘氨酸 | CAS号2566-20-3 N-苄氧羰基-L-亮氨酰甘氨酰甘氨酸 | CAS号23380-20-3 2-[[2-[(2-forma... | CAS号28320-73-2 N-[N-[N-[叔丁氧羰基]...

Fmoc-甘氨酸置于ethyl(Hydroxyimino) Cyanoacetate,N,N'-二异丙基碳二亚胺,哌啶体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 0.33H,反应生成 甘氨酰-甘氨酰-甘氨酸
参考文献:用于评估难溶性分选酶 A 抑制剂文库对医学相关细菌的抗菌活性,毒性和酶抑制的优化方案
标题:用于评估难溶性分选酶 A 抑制剂文库对医学相关细菌的抗菌活性,毒性和酶抑制的优化方案
摘要:增加抗菌素耐药性是一个主要的全球健康问题.传统抗生素施加选择压力,从而促进耐药微生物的积累.相比之下,抗毒力策略是不太有效的抗菌剂,但不太可能选择耐药性,可以与现有的抗生素结合以提高其活性,并且在某些情况下可以克服对其他抗菌剂的抗菌素耐药性.sortase A 抑制剂 (Srtais) 代表了这一类的一个令人兴奋的例子.然而,许多报道的例子表明水溶性差,这使它们的生物学评估和活性变得复杂.这包括使用有机溶剂的抗菌浓度或无法溶解这些化合物的条件进行最小抑制浓度 (Mic) 评估的报告.在此处,反式查耳酮 (Tc),黄连素 (Br),姜黄素 (Cur) 和槲皮素 (Qc)),包括对各种共溶剂浓度影响的比较评估,以及它们对多种疾病相关细菌的抗菌活性的比较评估菌株(甲氧西林敏感和耐药金黄色葡萄球菌,大肠杆菌和铜绿假单胞菌),分选酶 A 酶的抑制和对哺乳动物细胞 (Hek-293) 的毒性,使用这些优化的条件.在
DOI:10.1016/j.Bmc.2021.116527

专利信息

专利号:US-11053227-B2
优先权日:2017-12-20
标 题:Process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction and novel synthesis intermediates
发明人：COLLI CORRADO; BERTOLINI GIORGIO; SADA MARA; GARIS FARIS; NISIC FILIPPO; BIANCHI ALDO; BIAGGI CINZIA; DI FABIO ROMANO; RONZONI SILVANO; BERTUOLO STEFANIA; PRANDI ADOLFO; MAIORANA STEFANO
权利人:OLON SPA
摘要:Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention are also said novel synthesis intermediates and the use thereof in the preparation of active pharmaceutical ingredients, among which vilanterol and the salts thereof.

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-6040423-A
优先权日:1990-08-31
标题 :Process for synthesis of peptides
发明人：FRANK RONALD; GULER SINAN
权利人:BIOTECHNOLOG FORSCHUNG GMBH
摘要:The invention relates to a process for the rapid synthesis of support-bound or free peptides, a device for carrying out the process, a flat material with peptides bound to it which are prepared according to the process, and to a use for the flat material.

专利号:US-12024731-B2
优先权日:2017-05-03
标 题 :Methods and enzyme catalysts for the synthesis of non-canonical amino acids
发明人：BOVILLE CHRISTINA E; BRINKMANN-CHEN SABINE; BULLER ANDREW R; ROMNEY DAVID K; PRIER CHRISTOPHER K; KOCH PHILIPP; SCHEELE REMKES A
权利人:CALIFORNIA INST OF TECHN
摘要:The present disclosure provides methods for preparing β-substituted tryptophan compounds. The methods include: combining i) an unsubstituted indole or a substituted indole, ii) a β-substituted serine, and iii) a tryptophan synthase β-subunit (i.e., a TrpB); and maintaining the resulting mixture under conditions sufficient to form the β-substituted tryptophan. The TrpB contains at least one amino acid mutation which promotes formation of an amino-acrylate intermediate. New TrpB variants and new β-substituted tryptophan analogs are also described.

专利号:US-6110668-A
优先权日:1996-10-07
标 题:Gene synthesis method
发明人：STRIZHOV NICOLAI; KONCZ CSABA; SCHELL JEFF
权利人:MAX PLANCK GESELLSCHAFT
摘要:A method of gene synthesis is disclosed. The gene synthesis method permits the codons of [m] natural gene to be changed to allow preferential transcription and translation of the synthetic gene in transgenic organisms. The method utilizes a combination of enzymatic and chemical synthesis of DNA and significantly reduces the cost, time and number of steps required for construction of synthetic genes.

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.