CAS: 7245-02-5; 3-Methoxy-2-Phenyl-4H-Chromen-4-One

上下游产品

2-phenyl-chroman-3,4-dione dimethyl sulfate methanol (E)-2'-hydroxy-chalcone 1-Phenylindan-1,3-diol 3-methoxy-4-thioflavone 3-phenyl-4-methoxy-5-(o-hydroxyphenyl)-isoxazole 2'-Hydroxy-2-methoxyacetophenone

📜5H-Isochromeno[4,3-B]Chromen-12-Ium;Perchlorate置于trinitrate De Thallium,氢气体系中,化学反应生成 3-甲氧基黄酮
参考文献:Cis-Dimethoxylation De Perchlorates D'Alkoxy-3 Flavylium.
标题:Cis-Dimethoxylation De Perchlorates D'Alkoxy-3 Flavylium.
摘要:
DOI:10.1016/s0040-4039(01)81482-9

专利信息

专利号:US-7816544-B2
优先权日:2004-03-23
标 题:Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species
发明人：JONES II GUILFORD; GERARD BAUDOUIN; PORCO JR JOHN A
权利人:UNIV BOSTON
摘要:The present invention provides new strategies for the synthesis of compounds of the rocaglamide family and related natural products. In particular, the new biomimetic synthetic approach involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative followed by 1,3-dipolar cycloaddition of the oxidopyrylium species to a dipolarophile. This approach can be used for the formation of adducts containing an aglain core structure. Methods for the conversion of aglain core structures to aglain, rocaglamide and forbaglin ring systems are also provided. The present invention also relates to the use of rocaglamide/aglain/forbaglin derivatives for the manufacture of medicaments for use in the treatment of cancer or cancerous conditions, disorders associated with cellular hyperproliferation, or NF-κB-dependent conditions.

专利号:US-2008177093-A1
优先权日:2004-03-23
标题 :Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species

专利号:WO-2005092876-A1
优先权日:2004-03-23
标 题 :Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species

专利号:US-2011065786-A1
优先权日:2004-03-23
标题:Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species

专利号:EP-1493431-B1
优先权日:2003-07-03
标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
发明人：WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
权利人:MERCK PATENT GMBH
摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

专利号:CA-2560740-A1
优先权日:2004-03-23
标 题:Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species