CAS: 10402-90-1; 3-(4-(2-Ethoxy-2-Phenylethyl)Piperazin-1-yl)-2-Methyl-1-Phenylpropan-1-One

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CAS号54749-87-0 1-(2-Ethoxy-2-p... | CAS号93-55-0 苯丙酮

合成工艺路线路线简述

    📜2-Ethoxy-2-Phenylethan-1-Amine,3-[bis(2-Chloroethyl)Amino]-2-Methyl-1-Phenylpropan-1-One 反应生成易咳嗪
    参考文献:Murakami,Yasusi
    标题:Murakami,Yasusi

    专利信息


    专利号:US-2014378538-A1
    优先权日:2011-12-14
    标 题:Methods of responding to a biothreat
    发明人:BANCEL STEPHANE
    权利人:MODERMA THERAPEUTICS INC
    摘要:The present disclosure provides for devices, in particular mobile devices, which may be used in the synthesis of modified nucleic acid molecules, in particular modified mRNA molecules. The device for making the modified nucleosides, modified nucleotides and modified nucleic acids (e.g., mRNA) disclosed herein may be mobile devices comprising at least one sample block for insertion of one or more sample vessels, a device base with electronic control units for the sample block, a voltage supply, and one or more reagent(s) for the synthesis of at least one nucleic acid.

    专利号:US-9790531-B2
    优先权日:2012-08-14
    标 题 :Enzymes and polymerases for the synthesis of RNA
    发明人:WANG YUXUN; RAMAKRISHNAN DIVAKAR; DE FOUGEROLLES ANTONIN; WHORISKEY SUSAN
    权利人:MODERNATX INC
    摘要:The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.

    专利号:US-2024002331-A1
    优先权日:2022-06-08
    标 题 :Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
    发明人:ALI MIR; BOESCH AUSTIN WAYNE; DRUMMOND DARYL CLARK; KUHLMAN WILLIAM; NIELSEN ULRIK
    权利人:TIDAL THERAPEUTICS INC
    摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

    专利号:US-2025205169-A1
    优先权日:2023-12-13
    标 题:Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
    发明人:ALI MIR
    权利人:TIDAL THERAPEUTICS INC
    摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

    专利号:US-2015211039-A1
    优先权日:2012-08-14
    标题:Enzymes and polymerases for the synthesis of rna

    专利号:WO-2014028429-A2
    优先权日:2012-08-14
    标 题 :Enzymes and polymerases for the synthesis of rna

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Krautscheid Y, Senning CJ, Sartori SB, Singewald N, Schuster D, Stuppner H. Pharmacophore modeling, virtual screening, and in vitro testing reveal haloperidol, eprazinone, and fenbutrazate as neurokinin receptors ligands. J Chem Inf Model. 2014 Jun 23;54(6):1747-57. doi: 10.1021/ci500106z. Epub 2014 Jun 12. doi: 10.1016/j.ijpharm.2008.11.007. Epub 2008 Nov 18. French. French. German. German. German. French. German. German. German. German. Japanese. French. Japanese. Japanese. Japanese. German.

    合成参考文献


    摘要:U.S. Patent 3,448,192.
    摘要:Oyo Yakuri. Pharmacometrics., 2(314), 1968
    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
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