📜三氯化铝置于sodium Nitrite体系中,化学反应生成亚硝酰氯 参考文献:Noyes,W. A.,Journal Of The American Chemical Society,1925,Vol. 47,P. 2163 标题:Noyes,W. A.,Journal Of The American Chemical Society,1925,Vol. 47,P. 2163
专利信息
专利号:US-6096898-A 优先权日:1999-10-22 标 题:One pot synthesis of 1,2,4-triazoles 发明人:PODHOREZ DAVID E; HULL JR JOHN W; BRADY CHRISTINE H 权利人:DOW AGROSCIENCES LLC 摘要:One pot synthesis of 1,2,4-triazoles uses thioimidate intermediate and 1,2-dichloroethane solvent.
专利号:US-4045422-A 优先权日:1974-04-15 标题 :Synthesis of α-nitrosoketal dimers 发明人:ROGIC MILORAD M; SWERDLOFF MICHAEL D; DEMMIN TIMOTHY R 权利人:ALLIED CHEM 摘要:Ketals of α-oximinoketones and methods for the preparation of these compounds including intermediates are described. The compounds disclosed include both α-oximinoketals and cyclic ketals of α-oximinoketones. Also disclosed is a class of α-nitrosoketal dimers produced during the synthesis of the corresponding α-oximinoketals and the method for their preparation.
专利号:US-6770763-B2 优先权日:2002-06-11 标题 :Asymmetric synthesis of amino-pyrrolidinones 发明人:MAGNUS NICHOLAS A; CONFALONE PASQUALE N; SAVAGE SCOTT A; YATES MATTHEW; WALTERMIRE ROBERT E; MELONI DAVID J; CAMPAGNA SILVIO 权利人:BRISTOL MYERS SQUIBB CO 摘要:A novel process for the asymmetric synthesis of an amino-pyrrolidinone of the type shown below from appropriate pyrrolidinones is described.These compounds are useful as intermediates for MMP and TACE inhibitors.
专利号:US-7737284-B2 优先权日:2001-01-18 标题 :Synthesis of temozolomide and analogs 发明人:KUO SHEN-CHUN; MAS JANET L; HOU DONALD CHEN-TUNG 权利人:SCHERING PLOUGH CORP 摘要:This invention relates to a novel process for the synthesis of Temozolomide, an antitumor compound, and analogs, and to intermediates useful in this novel process.
专利号:EP-0097994-B1 优先权日:1982-06-24 标 题:Method for the solid-phase synthesis of retro-inverso polypeptides 摘要:This invention relates to a method for the solid-phase synthesis of polypeptides containing retro-inverted peptide bonds, using polydimethylacrylamide-co-acryloylsarcosimethylester resin cross-linked with N, N min -ethylene-bis-acrylamide as the insoluble support for lengthening the polypeptide chain in stages by the addition of suitable amino acid derivatives and/or peptides in succession. In particular, the method described in the present invention allows the easy preparation, on the polymer matrix, of monoacylated gem-diamino residues using the reagent I, I-bis (trifluoroacetoxy) iodobenzene in mixed aqueous-organic solvents.
专利号:US-8012993-B2 优先权日:2006-12-28 标题 :Stable S-nitrosothiols, method of synthesis and use 发明人:MOLINER JOSE REPOLLES; COY FRANCISCO PUBILL; MANCINI MARISABEL MOURELLE; NIETO JUAN CARLOS DEL CASTILLO; LLORENTE LYDIA CABEZA; BONIN JUAN MARTINEZ; SALADRIGAS ANA MODOLELL 权利人:LACER SA 摘要:The present invention relates to stable S-nitrosothiols derivatives of formula (I) n nhaving vasodilating effect and which inhibit the aggregation of the platelets and which therefore are useful for the preparation of medicaments for treatment of NO related diseases. The invention also relates to a process for the synthesis of the compounds of formula (I).
摘要:Chiba, S.; Narasaka, K., Science of Synthesis Knowledge Updates, (2011) 4, 449. 摘要:Chiba, S.; Narasaka, K., Science of Synthesis Knowledge Updates, (2011) 4, 448. 摘要:Treacy, S. M.; Zhang, X.; Rovis, T., Science of Synthesis, (2021) , 627. 摘要:Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 832 摘要:IATA. Dangerous Goods Regulations. 38th ed. Montreal, Canada and Geneva, Switzerland: International Air Transport Association, Dangerous Goods Board, January, 1997., p. 187