CAS: 19396-03-3; Polyoxin A

专利信息

专利号:US-5110929-A
优先权日:1986-08-07
标题 :Process for the preparation of N-alkylated quaternary nitrogen containing aromatic heterocycles
发明人：PARADIES HENRICH H
权利人:MEDICE CHAM PHARM FABRIK PUTTE
摘要:The synthesis of 4-, 4-(1,1)-and 3,5-substituted N-alkyl-pyridinium salts as well as of 2-carboxamide substituted N(1,4)diazinium compounds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10-5 -10-7 Mol/Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharmaceuticals.

专利号:US-5112844-A
优先权日:1986-08-07
标 题:Imidazole derivatives and use as anti-bacteria, anti-fungal and anti-viral agents
发明人：PARADIES HENRICH H
权利人:PUETTER MEDICE CHEM PHARM
摘要:The synthesis of quaternary five membered N-n-alkyl-heterocycles, especially of 4-hydroxy-N(1)-n-alkyl-imidazolium, 2,5-substituted N(3)-n-alkyl-thiazolium and substituted N(2) pyrazolium salts are described. The N-surfactants obtained have a very small critical micelle concentration (CMC) of 10-5-10-7 Mol/Liter, and are capable of forming micelles of different sizes and forms depending on the nature of the anions. The N-detergents can be used as pharmaceuticals.

专利号:US-5118808-A
优先权日:1986-08-07
标 题 :Pharmaceutical preparations
发明人：PARADIES HENRICH H
权利人:PUETTER MEDICE CHEM PHARM
摘要:The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration (CMC) in the order of 10 -5 -10 -7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

专利号:US-5133973-A
优先权日:1986-08-07
标 题:Pharmaceutical preparations
发明人：PARADIES HENRICH
权利人:PUETTER MEDICE CHEM PHARM
摘要:The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration (CMC) in the order of 10-5-10-7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

专利号:US-5057518-A
优先权日:1986-08-07
标题:Pharmaceutical preparations
发明人：PARADIES HENRICH H
权利人:MEDICE HEM PHARM FABRIK PUTTER
摘要:The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration (CMC) in the order of 10-5-10-7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

专利号:US-5143917-A
优先权日:1986-08-07
标题 :Pharmaceutical preparations
发明人：PARADIES HENRICH H
权利人:PUETTER MEDICE CHEM PHARM
摘要:The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration ()CMC) in the order of 10-5-10-7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.