CAS: 101-60-0; Porphine

该化合物是一种循环有机化合物,其特点是由四根甘蓝环组成的大型平板结构,由光桥连接在一起,这种独特的安排使得以与金属离子协调,形成金属洛托弗林,这些在血球和叶绿素等生物系统中至关重要.Porphyrin在电磁频谱可见的区域表现出强烈的吸收,导致其动态颜色,经常用于染色和颜料.它们通常溶于有机溶剂,在各种条件下表现出高度稳定性.此外,porphyrin可以参与各种化学反应,包括氧化和减少,使其在催化和光动力疗法中具有价值.它们形成金属复合的能力也加强了其在各种生物化学过程中的作用,包括电子转移和氧迁移.

结构式图片

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    专利信息


    专利号:US-2008086013-A1
    优先权日:2006-06-15
    标 题:Carbometallation of alkynes and improved synthesis of uniquinones
    发明人:LIPSHUTZ BRUCE H
    权利人:UNIV CALIFORNIA
    摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

    专利号:US-2006167289-A1
    优先权日:2003-12-05
    标题 :Practical, cost-effective synthesis of ubiquinones
    发明人:LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
    权利人:ZYMES LLC
    摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

    专利号:US-8618281-B2
    优先权日:2006-01-03
    标 题 :Geometric synthesis of porphyrin rods
    发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D
    权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE
    摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.

    专利号:US-6524446-B2
    优先权日:2001-03-27
    标 题 :Process for synthesis of a porphyrin compound using a molecular sieve catalyst under microwave irradiation
    发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; MOTKURI RADHA KISHAN; NAGABANDI SRINIVAS
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention provides an improved process for synthesis of porphyrin compounds of the general formula 1 n from pyrrole and aromatic aldehyde over zeolite molecular sieve catalysts using microwave heating, (solvent free) to provide an eco-friendly, economical, faster and selective heterogeneous method.

    专利号:US-4783529-A
    优先权日:1985-12-03
    标题 :Rapid synthesis of radiolabeled porphyrin complexes for medical application
    发明人:LAVALLEE DAVID K; MANSUY DANIEL; BATTIONI JEAN-PAUL
    权利人:RES CORP TECHNOLOGIES INC
    摘要:This invention relates to a novel method for the rapid synthesis of radiolabeled porphyrin complexes which are highly useful for biomedical application, i.e. conjugation to protein antibodies for use in tumor imaging and internal radiation therapy.

    专利号:US-6916982-B2
    优先权日:2000-07-21
    标题:Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays
    发明人:LOEWE ROBERT S; TOMIZAKI KIN-YA; LINDSEY JONATHAN S
    权利人:UNIV NORTH CAROLINA STATE
    摘要:The present invention provides methods, compounds, and compositions for the synthesis of light harvesting arrays, such arrays comprising: (a) a first substrate comprising a first electrode; and (b) a layer of light harvesting rods electrically coupled to said first electrode, each of said light harvesting rods comprising a polymer of Formula I:n nX 1 X m+1 ) m   (I)n nwherein m is at least 1; X 1 is a charge separation group, and X 2 through X m+1 are chromophores. At least one of X 2 through X m+1 has at least one perylene group coupled thereto.
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    合成参考文献


    参考文献:10.1007/s00894-010-0644-5
    摘要:Gheidi M, Safari N, Zahedi M. Theoretical investigation of the ring opening process of verdoheme to biliverdin in the presence of dioxygen. Journal of Molecular Modeling. 2010 Feb 16;16(8):1401–13. doi: 10.1007/s00894-010-0644-5.
    参考文献:10.1039/c1pp05074e
    摘要:Cormick MP, Quiroga ED, Bertolotti SG, Gabriela Alvarez M, Durantini EN. Mechanistic insight of the photodynamic effect induced by tri- and tetra-cationic porphyrins on Candida albicans cells. Photochemical & Photobiological Sciences. 2011 Oct;10(10):1556–61. doi: 10.1039/c1pp05074e.
    参考文献:10.1039/c1pp05125c
    摘要:Keane PM, Kelly JM. Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides. Photochemical & Photobiological Sciences. 2011 Oct;10(10):1578–86. doi: 10.1039/c1pp05125c.
    参考文献:10.1007/978-1-61779-188-8_7
    摘要:Bøe S, Prasmickaite L, Engesæter B, Hovig E. Light-directed delivery of nucleic acids. Methods Mol Biol. 2011;764():107–21. doi: 10.1007/978-1-61779-188-8_7.
    参考文献:10.1007/s00775-011-0816-5
    摘要:Ghosh A. Ab initio wavefunctions in bioinorganic chemistry: More than a succès d’estime JBIC Journal of Biological Inorganic Chemistry. 2011 Jul 14;16(6):819–20. doi: 10.1007/s00775-011-0816-5.
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