CAS: 138-14-7; N1-(5-(4-((5-Aminopentyl)Amino)-4-Oxobutanamido)Pentyl)-N1-Hydroxy-N4-(5-(N-Hydroxyacetamido)Pentyl)Succinamide Methanesulfonate

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CAS号110-15-6 琥珀酸； 丁二酸 | CAS号64-19-7 冰醋酸

去铁胺,甲烷磺酸置于甲磺酸去铁敏,乙醇体系中,用 乙醇,水 用作溶剂,化学反应 24.0H,以to Yield Deferoxamine B Mesylate (299 G) With A Purity Of 98% (W/w)的收率获得甲磺酸去铁敏
参考文献:Multistage Process For The Preparation Of Highly Pure Deferoxamine Mesylate Salt
标题:Multistage Process For The Preparation Of Highly Pure Deferoxamine Mesylate Salt
摘要:本发明提供了一种纯化工艺,通过该工艺,由微生物产生的脱铁胺b与微生物产生的其他聚羟酰胺混合物可以转化为其甲磺酸盐,该甲磺酸盐基本上不含其他聚羟酰胺和氯离子.该过程包括将脱铁胺b吸附和脱附在吸附树脂上,从吸附树脂的洗脱液中直接沉淀脱铁胺自由碱,将脱铁胺b自由碱与甲磺酸接触,并通过沉淀分离脱铁胺b甲磺酸盐.该工艺最小化了脱铁胺b的分解.

专利信息

专利号:US-5367113-A
优先权日:1991-10-30
标题 :Method for synthesis of desferrioxamine B, analogs and homologs thereof
发明人：BERGERON JR RAYMOND J
权利人:UNIV FLORIDA
摘要:Synthesis of desferrioxamine B and analogs and homologs thereof beginning with O-protected, N-protected hydroxylamine, which is N-alkylated to produce a protected N-4-cyanoalkylhydroxylamine which is acylated with a suitable anhydride. The resulting half-acid amide is subjected to a series of high yield condensations and reductions which vide desferrioxamine B in high overall yield. Alternatively, polyether analogs of desferrioxamine B can be prepared by reacting an activated polyether with the O-protected, N-protected hydroxylamine and subjecting the resulting product to a series of similar steps.

专利号:WO-2025007089-A1
优先权日:2023-06-30
标 题:Compositions, methods and kits for nucleic acids synthesis and amplification
发明人：BERKMAN JENNIFER; URBONAS IGNAS; ABREU DANIELA CRUZ; LIU CHENGJING; YEN CHIA AN; ONG KIMBERLIE SOOHOO; WEI WEI; GOMEZ SILVAN MARIA CINTA
权利人:LIFE TECHNOLOGIES CORP; THERMO FISHER SCIENTIFIC BALTICS UAB
摘要:The present disclosure is directed to compositions, methods and kits useful for the synthesis of nucleic acid molecules. More specifically, compositions, methods and kits are provided for the amplification of nucleic acid molecules in an one-step qPCR or RT-qPCR procedure comprising a reverse transcriptase, a DNA polymerase, at least one dNTP, and at least one stabilizing agent, wherein said at least one stabilizing agent increases stability of an assembled polymerase chain reaction.

专利号:US-2015359913-A1
优先权日:2013-01-25
标题:Tetrazines/trans-cyclooctenes in solid phase synthesis of labeled peptides
发明人：REINER THOMAS; LEWIS JASON STUART; WEISSLEDER RALPH; ZEGLIS BRIAN
权利人:SLOAN KETTERING INST CANCER; GEN HOSPITAL CORP
摘要:This invention is in the field of labeled peptide construction for medical treatment and analysis. The invention relates to synthetic labeled peptide compositions, methods of synthesis, and methods of use for the synthetic labeled peptide compositions for medical treatment, imaging, and research purposes.

专利号:US-9005895-B2
优先权日:2010-06-21
标题:Compositions, methods and kits for nucleic acid synthesis and amplification
发明人：WOO CORA L; BERKMAN JENNIFER; YIM PRISCILLA W
权利人:WOO CORA L; BERKMAN JENNIFER; YIM PRISCILLA W; LIFE TECHNOLOGIES CORP
摘要:The present invention is directed to compositions, methods and kits useful for the synthesis of nucleic acid molecules. More specifically, compositions, methods and kits are provided for the amplification of nucleic acid molecules in a one-step RT-PCR procedure comprising one or more agents used to increase tolerance to PCR inhibitors.

专利号:US-4861705-A
优先权日:1983-01-31
标 题:Method for removing components of biological fluids
发明人：MARGEL SHLOMO
权利人:YEDA RES & DEV
摘要:There are provided magnetic and non-magnetic agarose and agar polyaldehyde beads with diameters ranging from 40 microns up to 1 cm, and processes for the synthesis of such beads. The polyaldehyde compounds e.g. polyacrolein, polymethacrolein or polyglutaraldehyde, were used as microspheres or as powders. The agarose-polyaldehyde beads are capable of covalently binding in a single step, through their aldehyde groups, compounds containing primary amino groups or thiol groups, such as proteins, antibodies, enzymes and drugs. The beads are useful for various biological applications e.g. affinity chromatography, hemoperfusion, ion exchange resins, cell labeling, diagnostic purposes and cell separation.

专利号:WO-2024151591-A1
优先权日:2023-01-10
标 题 :Microwave-assisted synthesis of polyacrylic beads and the use thereof
发明人：TEHRANI ROUZBEH AFSARMANESH; ALIMOHAMMADI FARBOD
权利人:UNIV TEMPLE
摘要:A novel method of synthesizing polyacrylic beads, comprising the steps of suspending a monomer and a cross-linking agent in a solution, heating the solution in a microwave reactor, cooling the solution, and collecting the polyacrylic beads. The polyacrylic beads can be used in to remove solutes from various solutions, including blood, porcine blood, dialysate, serum, contaminated water, wastewater, and combinations thereof.