CAS: 22430-23-5; (3R,4S,5S)-5-((S)-1,2-Dihydroxyethyl)-3,4-Dihydroxydihydrofuran-2(3H)-One

该化合物是一个源自L-mannonic酸的圆形酯,其特点是乳腺结构,通过L-mannonic酸的碳盒酸组的分子化而形成,该化合物一般是白色的,是白色的,是非白色的固体,由于极性功能组而溶于水中.L-mannonic γ-内酯因其在碳水化合物化学中的作用而闻名,可能表现出生物活动,有可能影响代谢途径.其分子结构包括一个六人环,有助于其稳定性和再活动.该化合物可参与各种化学反应,包括水解和酯化,使其对合成有机化学和生物化学感兴趣.此外,该化合物可作为其他生物活性化合物合成的中间体,或碳水化合物衍生物的建筑块.

英文名称(3R,4S,5S)-5-((S)-1,2-Dihydroxyethyl)-3,4-Dihydroxydihydrofuran-2(3H)-One
中文名称(3R,4S,5S)-5-((S)-1,2-二羟基乙基)-3,4-二羟基二氢呋喃-2(3H)-酮
IUPAC名称(3R,4S,5S)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one
其它别名(3R,4S,5S)-5-((S)-1,2-二羟乙基)-3,4-二羟基二氢呋喃-2(3H)-酮; L-Mannono-1,4-Lactone
CAS编号22430-23-5
MFCD编号:MFCD00064332
EINECS号:228-678-5
分子式:C6H10O6
分子量:178.14
产品CID: 1160232
产品分类有机原料→分子砌块→脂肪杂环类化合物→四氢呋喃类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: SXZYCXMUPBBULW-KLVWXMOXSA-N
InChI=1S/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3-,4+,5-/m0/s1…
计算化学: 氢键受体数6.0氢键供体数4.0可旋转键数2.0

相似化合物

1128-23-0 6322-07-2 1198-69-2

物理性质

熔点153-155 °C
沸点467.9±18.0 °C at 760 mmHg
闪点201.5±14.7 °C
密度1.8±0.1 g/cm3
PH:-50.8 º (c=1, water)
pKa:12.06±0.60(预测)
PSA:107.22
LogP:-3.0132
旋光度-50.8º(C=1,WATER)
折射率1.625
蒸汽压0.0±2.6 mmHg at 25°C
溶解性DMSO (Slightly), Methanol (Slightly, Heated), Water (Sparingly)
敏感性常温常压下稳定避免氧化剂
外观形态白色至类白色固体
储存条件−20°C

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
安全声明H303+H313+H333
WGK Germany3

上下游产品

合成工艺路线路线简述

海关参考信息

2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2006084800-A1
优先权日:2004-06-30
标题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotropic distillation
发明人：CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.

专利号:WO-2006005071-A1
优先权日:2004-06-30
标题:Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotrophic distillation
发明人：CHENAULT H KEITH
权利人:DU PONT; CHENAULT H KEITH
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.

专利号:US-2006084817-A1
优先权日:2004-06-30
标题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging
发明人：CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Aldaric acids, aldonic acids, and their corresponding salts are cyclized to the corresponding lactone or dilactone using gas sparging to remove water.

专利号:WO-2006005070-A1
优先权日:2004-06-30
标题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging

专利号:JP-2008515769-A
优先权日:2004-06-30
标题:Synthesis of aldonolactone, aldarolactone, and aldodilactone using azeotropic distillation

专利号:JP-2008505122-A
优先权日:2004-06-30
标题 :Synthesis of aldonolactone, aldarolactone, and aldodilactone using gas sparging