CAS: 13007-92-6; Chromium(0) Hexacarbonyl

该化合物是铬的协调化合物,其特点是其八面形对地测量,中央铬原子环绕着6个一氧化碳(CO),这种化合物通常是在室内温度上挥发性,黄色的固体,以其高反活性和毒性闻名.六碳氢铬在苯和甲苯等有机溶剂中溶解,但在水中溶解较少.它经常用于有机合成,并用作含铬材料的前体.该化合物对空气和湿度十分敏感,在接触时形成氧化铬和二氧化碳.由于其毒性性质,在处理六碳酸铬时必须采取适当的安全防范措施,因为它会通过吸入或皮肤接触对健康造成危害.其独特的特性使它成为协调化学和工业应用的一个主题.

结构式图片

相似化合物

14040-11-0 13939-06-5 14516-54-2

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

carbon monoxide chromium(II) acetate chromium(III) fluoride chromium (III) ion(Z)-α,α'-dimethoxystilbene trans-α,α-dimethoxystilbene (η6-p-xylene)tricarbonylchromium(0) tricarbonyl(3-8-η-{2.2}paracyclophane)chromium

合成工艺路线路线简述

  • 合成目标产物 Chromium Hexacarbonyl 主要起始原料 Chromium, Pentacarbonyl[(Diethylamino)Phenylmethylene]-, (Oc-6-21)-
  • (文献来源)合成步骤主要原料 Chromium, Pentacarbonyl[(Diethylamino)Phenylmethylene]-, (Oc-6-21)-
三氯化铬置于一氧化碳,四氯化钛,Magnesium体系中,用 四氢呋喃 用作溶剂,以29-80的收率获得六羰基铬
参考文献:Magomedov,G. K.-I.; Morozova,L. V.; Sigachev,S. A.,Journal Of General Chemistry Of The Ussr,1988,Vol. 58,P. 433-435
标题:Magomedov,G. K.-I.; Morozova,L. V.; Sigachev,S. A.,Journal Of General Chemistry Of The Ussr,1988,Vol. 58,P. 433-435

专利信息


专利号:WO-9419366-A1
优先权日:1993-02-26
标题 :Chemical synthesis of squalamine
发明人:MORIARTY ROBERT M; GUO LIANG; TULADHAR SUDERSAN M
权利人:MAGAININ PHARMA
摘要:Methods for the chemical preparation or synthesis of the sterol antibiotic squalamine. Preferably, the preparation is by modifying the 3-position of a 3-oxo-7α-hydroxy-24z-ether protected alcohol group-5α-cholestane with a spermidino moiety to form a 3β-spermidino-7α-hydroxy-24z-ether protected group -5α-cholestane; deprotecting the 24-position of the 3β-spermidino-7α-hydroxy-24z-ether protected group-5α-cholestane to the free hydroxyl; and sulfating the 24-position of the 3β-spermidino-7α, 24-dihydroxy-5α-cholestane.

专利号:US-2014255328-A1
优先权日:2013-03-11
标 题:Hydrothermal Synthesis of Zinc Phlogopite
发明人:MCGUIRE MEAGHAN CLARK; BULL IVOR; JOHNSON GEOFFREY MARK
权利人:BASF SE
摘要:This invention relates to a synthetically derived zinc phlogopite platelets, of superior platelet diameter, effect pigments comprising such synthetically derived platelets and methods of forming said substrates. More specifically the disclosure describes an improved hydrothermal synthesis of zinc phlogopite suitable as a platelets for interference pigments, barrier and flame retardant applications.

专利号:US-6033624-A
优先权日:1995-02-15
标题 :Methods for the manufacturing of nanostructured metals, metal carbides, and metal alloys
发明人:GONSALVES KENNETH E; RANGARAJAN SRI PRAKASH
权利人:UNIV CONNETICUT
摘要:Methods for the manufacture of nanostructured metals, metal carbides, and metal alloys are presented, such metals including nanostructured aluminum, chromium, iron, molybdenum, vanadium, and steel. Preferably, the nanostructured steel is of the M50 type, and comprises iron, molybdenum, chromium, vanadium and carbon. Synthesis of M50 steel further comprising nanostructured aluminum, aluminum oxide, or aluminum nitride is also described. In accordance with an important feature of this invention, the grain size of the metals and metal alloys is in the nanometer range. In accordance with the method of the present invention, the nanostructured metals, metal carbides, and metal alloys are prepared via chemical synthesis from aluminum, iron, molybdenum, chromium and vanadium starting materials. Decomposition of metal precursors or co-precipitation or precipitation of metal precursors is followed by consolidation of the resulting nanostructured powders. Alternatively, nanostructured M50 steel may be obtained by mixing of nanocrystalline chromium, iron, molybdenum, and vanadium powders, followed by ball-milling, and consolidation. The nanostructured metals, metal carbides, and metal alloys of this invention find particular utility in the manufacture of cutting tools and bearings, and in ferrofluids, magnetic memory systems, and catalysis.

专利号:US-2004116724-A1
优先权日:1996-12-06
标 题:Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
发明人:KINNEY WILLIAM A; JONES STEVEN; ZHANG XUEHAI; RAO MEENA N; BULLIARD MICHEL; MECKLER HAROLD; LEE NANCY
摘要:A method is described for stereoselectively reducing an unsaturated alkyl ketone substituent attached to a fused ring base. In this method, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent. This reaction stereoselectively reduces the unsaturated alkyl ketone to an unsaturated alkyl alcohol. The unsaturated alkyl alcohol can be further reduced, if desired, to produce a saturated alkyl alcohol. The fused ring base can be, for example, a steroid ring base or a base of a vitamin D analog. The process in accordance with the invention can be used with an alkeneone substituent (e.g., a 22-ene-24-one substituent) or an alkyneone substituent (e.g., a 22-yne-24-one substituent) on a steroid ring base to make squalamine or other useful aminosterol compounds and intermediates for making aminosterol compounds.

专利号:US-7226661-B2
优先权日:2003-02-03
标题:Synthesis of quinones and phenols on solid support
发明人:MARTINEZ LUIS E
权利人:UNIV TEXAS
摘要:Generally, and in one form, the present invention is a method of making a benzene-modified compound on solid support that includes the steps of forming an (oxy)(aryl)carbene complex, esterifying the (oxy)(aryl)carbene complex to form an (ester)(aryl)carbene complex, and contacting the (ester)(aryl)carbene complex with a solid support such that the (ester)(aryl)carbene complex is bound to the solid support. In another form, the present invention includes compositions for the resulting (ester)(aryl)carbene complexes on solid support, such as any resulting solid support compounds formed after the initial coupling as well as those from any subsequent reaction, including those with linkers and on a solid support. The method and compositions of the present invention yield stable, durable, highly efficient and cost-effective as well as potentially biologically active lead compounds on solid support.

专利号:US-6610866-B2
优先权日:1996-12-06
标 题 :Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
发明人:KINNEY WILLIAM A; JONES STEVEN; ZHANG XUEHAI; RAO MEENA N; BULLIARD MICHEL; MECKLER HAROLD; LEE NANCY
权利人:MAGAININ PHARMA
摘要:A method is described for stereoselectively reducing an unsaturated alkyl ketone substituent attached to a fused ring base. In this method, the unsaturated alkyl ketone reacts with a chiral oxazaborolidine reagent. This reaction stereoselectively reduces the unsaturated alkyl ketone to an unsaturated alkyl alcohol. The unsaturated alkyl alcohol can be further reduced, if desired, to produce a saturated alkyl alcohol. The fused ring base can be, for example, a steroid ring base or a base of a vitamin D analog. The process in accordance with the invention can be used with an alkeneone substituent (e.g., a 22-ene-24-one substituent) or an alkyneone substituent (e.g., a 22-yne-24-one substituent) on a steroid ring base to make squalamine or other useful aminosterol compounds and intermediates for making aminosterol compounds.
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合成参考文献


摘要:Aitken, R. A.; Aitken, K. M., Science of Synthesis, (2010) 47, 1028.
摘要:Kosarev, S. A., Science of Synthesis Knowledge Updates, (2012) 2, 236.
摘要:L532: The Physical and Theoretical Chemistry Laboratory of Oxford University (2005). Material Safety Data Sheet (MSDS) for hexacarbonyl chromium.
摘要:Cellnik, T.; Jo, W.; Healy, A., Science of Synthesis: Knowledge Updates, (2024) 2, 366.
参考文献:10.1007/s11745-999-0399-z
摘要:Grandgirard A, Sergiel JP, Nour M, Demaison-Meloche J, Giniès C. Lymphatic absorption of phytosterol oxides in rats. Lipids. 1999 Jun;34(6):563–70. doi: 10.1007/s11745-999-0399-z.
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