网站主页>>>研发精选>>>临床前CDMO研发筛选相关化合物
CDMO是Contract Development and Manufacturing Organization的缩写,即合同定制研发生产组织。它是一种为制药企业及生物技术公司提供医药(特别是创新药)工艺研发及制备、工艺优化、放大生产、注册和验证批生产以及商业化生产等定制服务的机构. 在传统代工基础上增加了研发和工艺优化能力,是高技术壁垒的工艺研发能力与规模生产能力的深度结合. 1, 工艺开发与优化:创新性合成路线设计、工艺参数优化. 2, 中试放大:实验室工艺向规模化生产的转化 3, 注册批生产:支持客户新药申报的验证批生产. 4, 商业化生产:药品上市后的大规模生产供应. 全球医药CDMO行业保持较高景气度。根据弗若斯特沙利文预测:2026年全球CDMO市场规模:预计达1,189亿美元 2033年全球CDMO市场规模:预计达3,385亿美元. CDMO作为医药产业链专业化分工的产物,已经从单纯的CMO代工模式升级为"研发+生产"一体化的高附加值服务。当前,在多肽、ADC、CGT等新型药物赛道的驱动下,全球及中国CDMO市场保持高速增长。中国CDMO企业凭借完整的供应链体系、工程师红利和一体化服务能力,全球市占率有望持续提升,行业正从"成本优势"竞争迈向"体系优势"竞争的新阶段。
如有产品调研服务, 请致函联系我们

客户展示

示例图片

临床前CDMO研发化合物筛选

  • Homoharringtonine (CGX-635)

    中文名称:高三尖杉酯碱
    CAS号:26833-87-4
    分子式: C29H39NO9 分子量: 545.62
    产品形式: free Base
    研发状态: Recruiting
    研发用途: Hereditary Hemorrhagic Telangiectasia; Arteriovenous Malformations; Telangiectasia; Epistaxis; GastroIntestinal Bleeding; Cerebral Arteriovenous Malformations; Vascular Malformation
    研究机构: Cure HHT; Augusta University; The Cleveland Clinic; Mayo Clinic; Massachusetts General Hospital; Columbia University; Oregon Health and Science University; University of California Los Angeles; University of California San Francisco; University of Colorado Denver; University of North Carolina Chapel Hill; University of Pennsylvania; University of Texas; University of Utah; Washington University School of Medicine; Yale University; Health Resources and Services Administration (HRSA); Children''s Hospital of Philadelphia
    研发日期: November 13 2023
    研发阶段: --
    Homoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.

  • Indapamide

    中文名称:吲达帕胺
    CAS号:26807-65-8
    分子式: C16H16ClN3O3S 分子量: 365.83
    产品形式: free base
    研发状态: Unknown status
    研发用途: Pharmacogenomics
    研究机构: Ain Shams University
    研发日期: March 15 2022
    研发阶段: Phase 4
    Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

  • Amoxicillin

    中文名称: 阿莫西林
    CAS号:26787-78-0
    分子式: C16H19N3O5S 分子量: 365.40
    产品形式: Free Base
    研发状态: Recruiting
    研发用途: Penicillin Allergy
    研究机构: Geisinger Clinic
    研发日期: March 4 2024
    研发阶段: Early Phase 1
    Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.

  • Canertinib (CI-1033)

    中文名称:卡奈替尼
    CAS号:267243-28-7
    分子式: C24H25ClFN5O3 分子量: 485.94
    产品形式: Free Base
    研发状态: Completed
    研发用途: Lung Neoplasms
    研究机构: Pfizer
    研发日期: Jan-03
    研发阶段: Phase 2
    Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.

  • Reparixin (Repertaxin)


    CAS号:266359-83-5
    分子式: C14H21NO3S 分子量: 283.39
    产品形式: free base
    研发状态: Recruiting
    研发用途: Myelofibrosis (PMF); Post Essential Thrombocythemia Myelofibrosis (ET-MF); Post Polycythemia Vera Related Myelofibrosis (PV-MF)
    研究机构: Icahn School of Medicine at Mount Sinai; Dompé Farmaceutici S.p.A
    研发日期: June 27 2023
    研发阶段: Phase 2
    Reparixin (Repertaxin, DF 1681Y) is a potent and specific inhibitor of CXCR1 with IC50 of 1 nM. Reparixin (Repertaxin) inhibits PMN migration induced by CXCL8 (IC50 = 1 nM) and rodent PMN chemotaxis induced by CXCL1 and CXCL2. Repertaxin inhibits the response of human PMN to CXCL1, which interacts with CXCR2 (IC50 = 400 nM).

  • Endovion (NS 3728)

    中文名称:1-(3,5-双(三氟甲基)苯基)-3-(4-溴-2-(2H-四唑-5-基)苯基)脲
    CAS号:265646-85-3
    分子式: C16H9BrF6N6O 分子量: 495.18
    产品形式: Free base
    研发状态: Unknown status
    研发用途: Metastatic Colorectal Cancer
    研究机构: Scandion Oncology A/S; TFS Trial Form Support
    研发日期: May 14 2020
    研发阶段: Phase 1 : Phase 2
    Endovion (NS 3728, SCO-101) is a potent anion channel inhibitor that blocks the Volume Regulated Anion Channels (VRAC).

  • 免费注册, 助力研发,生产, 销售.

    招募中心

    我们的宗旨: 净化, 简洁, 高效Purifying, concise, efficient !我们的口号: 减少中间商赚差价!

    即日起可免费注册成为会员, 建立企业产品库, 免费上传产品目录, 企业介绍等. 让你的产品直接呈现给客户.

    试运营阶段,所有广告业务5折优惠

    分类广告投放

    依据化学成分的不同, 针对不同的企业和产品, 我们提供分类产品广告投放.

    客户展示

    示例图片
    优秀企业推荐
    ×

    通知