Biricodar CAS Registry Number: 159997-94-1 1,7-二(吡啶-3-基)庚烷-4-基(2S)-1-[2-氧代-2-(3,4,5-三甲氧基苯基)乙酰基]哌啶-2-羧酸酯
CAS Name: (2S)-1-[Oxo(3,4,5-trimethoxyphenyl)acetyl]-2-piperidinecarboxylic acid 4-(3-pyridinyl)-1-[3-(3-pyridinyl)propyl]butyl ester
Percent Composition: C 67.64%, H 6.85%, N 6.96%, O 18.55%
📌 参考资料/链接：
Literature References: Chemosensitizer that restores sensitivity to cytotoxic agents in multidrug resistant (MDR) cells. Prepn: D. M. Armistead et al., WO 9407858; eidem, US 5620971 (1994, 1997 both to Vertex). Effect on MDR mediated by P-glycoprotein: U. A. Germann et al., Anti-Cancer Drugs 8, 125 (1997); by multidrug resistance-associated protein (MRP): eidem, ibid. 141. Clinical pharmacology, pharmacokinetics: E. K. Rowinsky et al., J. Clin. Oncol. 16, 2964 (1998).
📄 详细内容
Derivative Type: Dicitrate
CAS Registry Number: 174254-13-8Trademarks: Incel (Vertex)
Percent Composition: C 55.92%, H 5.82%, N 4.25%, O 34.01%
Properties: Sol in water.
Therap-Cat: Antineoplastic adjunct (chemosensitizer).
Keywords: Antineoplastic Adjunct; Chemosensitizer.
产品链接: 159997-94-1››