Properties: Orthorhombic tablets from 5 parts methanol and 10 parts water. Very poisonous! Contains ½ mol H2O which is given up at 110° over P2O5 at 20 mm Hg. mp 171-175° with effervescence. Occasionally a few isolated crystals are found which melt at ~230°. [a]D25 +43.1° (c = 2.8 in methanol). Sol in alcohol, acetone, chloroform, benzene, and glacial acetic acid. Practically insol in water, ether, petr ether. Color reaction with H2SO4 and Ac2O like cholesterol. LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel).
Melting point: mp 171-175° with effervescence; Occasionally a few isolated crystals are found which melt at ~230°
Optical Rotation: [a]D25 +43.1° (c = 2.8 in methanol)
Toxicity data: LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)
Derivative Type: 3-Benzoylstrophanthidin
Percent Composition: C 70.85%, H 7.13%, O 22.02%
Properties: mp 230°. [a]D26 +47.8° (c = 1.07 in acetone).
Melting point: mp 230°
Optical Rotation: [a]D26 +47.8° (c = 1.07 in acetone)
Derivative Type: 3-(p-Bromobenzoyl)strophanthidin
Percent Composition: C 61.33%, H 6.00%, Br 13.60%, O 19.06%
Properties: mp 222-224°. [a]D20 +42.0° (c = 1.094 in acetone).
Melting point: mp 222-224°
Optical Rotation: [a]D20 +42.0° (c = 1.094 in acetone)
Derivative Type: Dihydrostrophanthidin
Percent Composition: C 67.96%, H 8.43%, O 23.61%
Properties: mp 100-103°, resolidifies and again melts at 190-195°. [a]D23 +34.9° (methanol).
Melting point: mp 100-103°
Optical Rotation: [a]D23 +34.9° (methanol)
Derivative Type: 16-Hydroxystrophanthidin
Additional Names: Strophadogenin
Percent Composition: C 65.69%, H 7.67%, O 26.63%
Properties: Long prisms from ethanol, dec 238-241°. [a]D23 +52.9° (c = 1.24 in 96% alc). uv max: 219 nm (log e 4.3).
Optical Rotation: [a]D23 +52.9° (c = 1.24 in 96% alc)
Absorption maximum: uv max: 219 nm (log e 4.3)
产品链接: 66-28-4››