Noformicin CAS Registry Number: 155-38-4 5-氨基-N-(3-氨基-3-亚氨基丙基)-3,4-二氢-2H-吡咯-2-甲酰胺
CAS Name: 5-Amino-N-(3-amino-3-iminopropyl)-3,4-dihydro-2H-pyrrole-2-carboxamide
Additional Names: N-(2-amidinoethyl)-5-imino-2-pyrrolidinecarboxamide; 2-[N-(2-amidinoethyl)carbamoyl]-5-iminopyrrolidine; b-(5-imino-2-pyrrolidinecarboxamido)propamidine; noformycin
Percent Composition: C 48.72%, H 7.67%, N 35.51%, O 8.11%
📌 参考资料/链接：
Literature References: Antiviral agent produced by Nocardia formica, culture no. N.R.R.L. 2470: Peck et al., US 2804463 (1957 to Merck Co.); Gray, Phytopathology 45, 281 (1955). Activity studies: Furusawa et al., Proc. Soc. Exp. Biol. Med. 116, 938 (1964); eidem, Med. Pharmacol. Exp. 12, 259 (1965). Synthesis of (+)- and (±)-forms: Diana, J. Med. Chem. 16, 857 (1973).
📄 详细内容
Derivative Type: (+)-Form dihydrochloride
Percent Composition: C 35.57%, H 6.34%, Cl 26.25%, N 25.92%, O 5.92%
Properties: The biologically active form. Crystals from methanol, dec 263-264°. [a]D25 +8.8° (methanol). Sol in water. Somewhat sol in organic solvents. pKa 9.4.
pKa: pKa 9.4
Optical Rotation: [a]D25 +8.8° (methanol)
Derivative Type: (±)-Form dihydrochloride
Properties: mp 252-254°.
Melting point: mp 252-254°
产品链接: 155-38-4››