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Isopropamide Iodide CAS Registry Number: 71-81-8 异丙碘胺

CAS Name: g-(Aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-g-phenylbenzenepropanaminium iodide
Additional Names: (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium iodide; 2,2-diphenyl-4-diisopropylaminobutyramide methiodideTrademarks: Darbid (SK F); Priamide (Janssen); Tyrimide
Percent Composition: C 57.50%, H 6.92%, I 26.41%, N 5.83%, O 3.33%

📌 参考资料/链接：
Literature References: Anticholinergic. Prepn: P. Janssen et al., Arch. Int. Pharmacodyn. 103, 82 (1955); M. E. Speeter, US 2823233 (1958 to Bristol). Crystal and molecular structure: N. Datta et al., J. Chem. Soc. Perkin Trans. 2 1977, 781. Comprehensive description: R. S. Santoro et al., Anal. Profiles Drug Subs. 2, 315-338 (1973); A. Post, R. S. Santoro, ibid. 12, 721-732 (1983).

📄 详细内容

Properties: Crystals or amorphous powder, mp 198-201° (dec) (Janssen); also reported as mp 189.0-191.5° (Santoro). Sensitive to light. Freely sol in boiling water, in methanol, ethanol, chloroform. Practically insol in ether.
Melting point: mp 198-201° (dec) (Janssen); mp 189.0-191.5° (Santoro)
Derivative Type: Free base
Percent Composition: C 78.06%, H 8.93%, N 8.28%, O 4.73%
Properties: mp 84-86°.
Melting point: mp 84-86°
NOTE: Ingredient of
Stelabid (SK F) (also contg trifluoperazine, q.v.).
Therap-Cat: Antispasmodic.
Therap-Cat-Vet: Antiemetic; antidiarrheal.
Keywords: Antimuscarinic; Antispasmodic.
产品链接: 71-81-8››

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