网站主页>>>
项目整合精选>>>
项目整合精选>>>Asoprisnil CAS Registry Number: 199396-76-4 (8S,11R,13S,14S,17S)-11-[4-[(E)-羟基亚氨甲基]苯基]-17-甲氧基-17-(甲氧基甲基)-13-甲基-1,2,6,7,8,11,12,14,15,16-十氢环戊烯并[a]菲-3-酮
Asoprisnil CAS Registry Number: 199396-76-4 (8S,11R,13S,14S,17S)-11-[4-[(E)-羟基亚氨甲基]苯基]-17-甲氧基-17-(甲氧基甲基)-13-甲基-1,2,6,7,8,11,12,14,15,16-十氢环戊烯并[a]菲-3-酮
CAS Name: [C(E)]-4-[(11b,17b)-17-Methoxy-17-(methoxymethyl)-3-oxoestra-4,9-dien-11-yl]benzaldehyde-1-oxime
Additional Names: 11b-[4-(hydroxyiminomethyl)phenyl]-17b-methoxy-17a-(methoxymethyl)estra-4,9-dien-3-onePercent Composition: C 74.80%, H 7.85%, N 3.12%, O 14.23%
📌 参考资料/链接：
Literature References: Selective progesterone receptor modulator. Prepn: G. Schubert et al., EP 648778; eidem, US 5693628 (1995, 1997 both to Jenpharm). Clinical effects on menstrual and ovarian cyclicity in premenopausal women: K. Chwalisz et al., Hum. Reprod. 20, 1090 (2005). Review of pharmacology and therapeutic potential: D. DeManno et al., Steroids 68, 1019-1032 (2003); of early clinical experience: K. Chwalisz et al., Semin. Reprod. Med. 22, 113-119 (2004).
📄 详细内容
Properties: Crystals from isopropanol + CH2Cl2, mp 118° (dec). [a]D +197° (CHCl3). uv max (methanol): 264, 299 nm (e 20366, 20228).
Melting point: mp 118° (dec)
Optical Rotation: [a]D +197° (CHCl3)
Absorption maximum: uv max (methanol): 264, 299 nm (e 20366, 20228)
Therap-Cat: In treatment of uterine fibroids.
Keywords: Selective Progesterone Receptor Modulator (SPRM).
产品链接: 199396-76-4››