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Etoperidone CAS Registry Number: 52942-31-1 依托哌酮

CAS Name: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one
Percent Composition: C 60.39%, H 7.47%, Cl 9.38%, N 18.53%, O 4.23%

📌 参考资料/链接：
Literature References: Psychotropic drug related structurally to trazodone, q.v. Prepn: G. Palazzo, DE 2351739; idem, US 3857845 (both 1974 to Angelini). Pharmacology and acute toxicity: R. Lisciani et al., Arzneim.-Forsch. 28, 417 (1978); M. T. Ramacci et al., ibid. 29, 294 (1979). Clinical evaluation: P. Bertoletti, G. Clin. Med. 58, 393 (1977). Teratology study: S. Barcellona et al., Toxicology 8, 87 (1977). Acute cardiovascular toxicity study: R. Lisciani et al., ibid. 10, 151 (1978).

📄 详细内容

Properties: Liq, bp0.5 230°.
Boiling point: bp0.5 230°
Derivative Type: Hydrochloride
CAS Registry Number: 57775-22-1Trademarks: Axiomin (Promeco); Depracer (Lepori); Etoran (Il Dong); Staff (Sigma-Tau); Tropene (Degussa)
Percent Composition: C 55.07%, H 7.05%, Cl 17.11%, N 16.90%, O 3.86%
Properties: Crystals from isopropanol, mp 197-198°. pH (2% aq soln): 4.1 ± 0.2. Sol in water, alc; slightly sol in chloroform. Practically insol in acetone, benzene, ether. LD50 in mice, rats (mg/kg): 580, 720 orally; 72, 62 i.v.; 135, 120 i.p. (Lisciani).
Melting point: mp 197-198°
Toxicity data: LD50 in mice, rats (mg/kg): 580, 720 orally; 72, 62 i.v.; 135, 120 i.p. (Lisciani)
Therap-Cat: Antidepressant.
Keywords: Antidepressant.
产品链接: 52942-31-1››

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