Derivative Type: l-Form
Properties: Needles from water, ethanol or ethyl acetate, mp 139-140°. [a]D25 -54° (c = 1 in methanol); [a]D25 -60° (c = 1 in ethanol). pK 5.1. Soluble in water, acetone, alcohol, ethylene dichloride, glacial acetic acid. Aq solns are stable over a wide pH range at room temp. Rapidly loses optical activity in dil alkali to give the racemate. Has in vitro activity against Mycobacterium tuberculosis, M. ranae and M. phlei. LD50 in mice (g/kg): 3.5 i.v., 2 s.c. (Miyake).
Melting point: mp 139-140°
pKa: pK 5.1
Optical Rotation: [a]D25 -54° (c = 1 in methanol); [a]D25 -60° (c = 1 in ethanol)
Toxicity data: LD50 in mice (g/kg): 3.5 i.v., 2 s.c. (Miyake)
Derivative Type: Methyl ester
Percent Composition: C 51.92%, H 7.41%, N 6.06%, O 20.75%, S 13.86%
Properties: Needles from ether + hexane, mp 53-54°. [a]D25 -50.9° (methanol).
Melting point: mp 53-54°
Optical Rotation: [a]D25 -50.9° (methanol)
Derivative Type: d-Form
Properties: Crystals, mp 138-139°. [a]D25 +57° (methanol).
Melting point: mp 138-139°
Optical Rotation: [a]D25 +57° (methanol)
Derivative Type: dl-Form
Properties: Crystals from water, mp 123°.
Melting point: mp 123°
产品链接: 539-35-5››