Coumetarol CAS Registry Number: 4366-18-1 库美香豆素
CAS Name: 3,3'-(2-Methoxyethylidene)bis[4-hydroxy-2H-1-benzopyran-2-one]
Additional Names: 3,3'-(2-methoxyethylidene)bis[4-hydroxycoumarin]; 1-methoxy-2,2-bis[4-hydroxy-3-coumarinyl]ethane; 4,4'-dihydroxy-3,3'-(2-methoxyethylidene)dicoumarin; 2,2-bis[4'-hydroxy-3'-coumarinyl]ethyl methyl ether; cumetharol; cumethoxaethaneTrademarks: Dicoumoxyl (Labaz); Dicumoxane (Boots)
Percent Composition: C 66.31%, H 4.24%, O 29.45%
📌 参考资料/链接：
Literature References: Prepn: Veldstra et al., Rec. Trav. Chim. 72, 358 (1953); GB 736388 and NL 80005 (both 1955 to N. V. Amsterdamsche Chininefabriek), C.A. 50, 10795a, 16874b (1956). Stereodynamics: Laruelle, Tetrahedron Lett. 1970, 2235. Has antivitamin K action. Activity studies: de Jongh, Kok, Arch. Int. Pharmacodyn. 94, 470 (1953); Gilgenkrantz et al., Ann. Med. Nancy 3, 115 (1964). Series of articles on clinical studies: Hutinel, Lyon Med. 23, 1569-1604 (1964).
📄 详细内容
Properties: Crystals from ethanol or methanol, mp 156-157°.
Melting point: mp 156-157°
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 4366-18-1››