CAS: 4366-18-1; 3,3'-(2-Methoxyethane-1,1-Diyl)Bis(4-Hydroxy-2H-Chromen-2-One)
该化合物是一种合成合成化合物,被归类为可塑性衍生物,主要以其用作抗凝胶剂而闻名;它具有抑制合成维生素K依赖性凝胶因素的特性,从而影响血液凝胶凝固;Coumetarol的特点是水溶性相对较低,影响其生物利用率和药用动力学;该化合物通常通过口服施用,具有很长的半衰期,允许在治疗用途中一次性施用;其行动机制包括竞争性抑制维生素K-过氧化再次吸附酶,这是维生素K再生的关键酶,对于合成凝固系数因素II,VII,IX和X至关重要. Coumetatarol的抗凝胶效应使其在预防和治疗血栓性失调方面有用.然而,与其他抗凝胶剂一样,它需要仔细监测以控制出血并发症的风险.
- ⚠️《化妆品禁用原料目录》
- 英文名称3,3'-(2-Methoxyethane-1,1-Diyl)Bis(4-Hydroxy-2H-Chromen-2-One)
- 中文名称库美香豆素
- IUPAC名称3,3'-(2-methoxyethane-1,1-diyl)bis(4-hydroxy-2H-chromen-2-one)
- 其它别名Cumetharol; 3,3'-(2-Methoxyethylidene)Bis(4-Hydroxycoumarin); Cumethoxethan; Dicoumoxyl; Dicumoxane; 2-Hydroxy-3-[1-(2-Hydroxy-4-Keto-Chromen-3-yl)-2-Methoxy-Ethyl]Chromone; 2-Hydroxy-3-[1-(2-Hydroxy-4-Oxo-Chromen-3-yl)-2-Methoxy-Ethyl]Chromen-4-One; 2-Hydroxy-3-[1-(2-Hydroxy-4-Oxochromen-3-yl)-2-Methoxyethyl]Chromen-4-One
- CAS编号4366-18-1
- MFCD编号:MFCD00865269
- EINECS号:224-455-1
- FDA UNII编号:UO1VQB3SPZ
- 分子式:C21H16O7分子量:380.35
- 产品CID: 1446716
- 产品分类有机原料 → 苯丙烷和聚酮 → 香豆素及其衍生物
物理性质
上下游产品
CAS号1076-38-6 4-羟基香豆素; 4-羟基-1... | CAS号4819-75-4 甲氧基乙醛二乙缩醛合成工艺路线路线简述
- 合成目标产物 Coumetarol 主要起始原料 4-Hydroxycoumarin And Methoxyacetaldehyde Diethyl Acetal
- (文献来源)合成步骤主要原料 4-Hydroxycoumarin 和 Methoxyacetaldehyde Diethyl Acetal
📜4-羟基香豆素,甲氧基乙醛二乙缩醛置于乙醇体系中,化学反应生成 库美香豆素
参考文献:Veldstra Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1953,Vol. 72,P. 358,361,364
标题:Veldstra Et Al.,Recueil Des Travaux Chimiques Des Pays-Bas,1953,Vol. 72,P. 358,361,364
海关参考信息
- 2902200000-苯
2909199090-其他醚及其衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/978-3-642-68912-3_79
摘要:Nobel A. C. 1983. In: Dictionary of Medical Objects / Medizinisches Sachwörterbuch / Dictionnaire d’Objets Médicaux / Medicinae Rerum Verborum Index.
参考文献:10.1007/978-3-031-75678-8_17
摘要:Rani R, Chanu SY, Sharma GS, Mondal N, Mohanty D. Genetic Enhancement of Leguminous Microgreens: A Frontier in Sustainable Nutrition. 2025. In: Recent Trends and Applications of Leguminous Microgreens as Functional Foods.
参考文献:10.1007/978-3-032-14975-6_6
摘要:Thakur A, Palvi, Patel SS, Das K. Harvesting, Postharvest Handling, and Minimal Processing of Microgreens. 2026. In: Microgreens: Production, Processing and Utilisation.
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