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Deptropine CAS Registry Number: 604-51-3 地普托品

CAS Name: endo-3-[(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane
Additional Names: 3a-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-1aH,5aH-tropane; dibenzheptropine
Percent Composition: C 82.84%, H 8.16%, N 4.20%, O 4.80%

📌 参考资料/链接：
Literature References: Prepn: Van der Stelt et al., J. Med. Pharm. Chem. 4, 335 (1961). Pharmacology: Funcke et al., Arch. Int. Pharmacodyn. 148, 135 (1964); Timmerman et al., ibid. 187, 291 (1970). Metabolism: Hespe et al., ibid. 164, 397 (1966).

📄 详细内容

Derivative Type: Citrate
CAS Registry Number: 2169-75-7Trademarks: Brontine (Yamanouchi)
Percent Composition: C 66.27%, H 6.71%, N 2.66%, O 24.35%
Properties: LD50 in mice (mg/kg): 32 i.v.; 300 orally (Timmerman).
Toxicity data: LD50 in mice (mg/kg): 32 i.v.; 300 orally (Timmerman)
Derivative Type: Maleate
Percent Composition: C 72.14%, H 6.95%, N 3.12%, O 17.80%
Properties: Crystals from ethanol, acetone, ethyl acetate or chloroform, mp 133-136°.
Melting point: mp 133-136°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.
产品链接: 604-51-3››

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