网站主页>>>项目整合精选>>>项目整合精选>>>Ranelic Acid CAS Registry Number: 135459-90-4 5-[二(羧甲基)氨基]-2-羧基-4-氰基-3-噻吩乙酸

Ranelic Acid CAS Registry Number: 135459-90-4 5-[二(羧甲基)氨基]-2-羧基-4-氰基-3-噻吩乙酸


CAS Name: 5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid
Additional Names: 2-[N,N-di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid
Percent Composition: C 42.11%, H 2.94%, N 8.18%, O 37.39%, S 9.37%
📌 参考资料/链接:
Literature References: Prepn: M. Wierzbicki et al., EP 415850; eidem, US 5128367 (1991, 1992 both to Adir Co.).

📄 详细内容


Properties: Crystals from ethyl ether, contains 4% ether.
Derivative Type: Strontium salt
CAS Registry Number: 135459-87-9
Additional Names: Strontium ranelateTrademarks: Osseor (Servier); Protelos (Servier); Protos (Servier)
Percent Composition: C 28.07%, H 1.18%, N 5.46%, O 24.93%, S 6.24%, Sr 34.13%
Literature References: Bone metabolism modulator; inhibits bone resorption while maintaining bone formation. Effect on human chondrocytes in vitro: Y. Henrotin et al., J. Bone Miner. Res.
16, 299 (2001). Effect on bone remodeling in monkeys: J. Buehler et al., Bone
29, 176 (2001). Clinical trial in postmenopausal osteoporosis: P. J. Meunier et al., N. Engl. J. Med.
350, 459 (2004).
Therap-Cat: Strontium salt as antiosteoporotic.
产品链接: 135459-90-4››