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Cyamemazine CAS Registry Number: 3546-03-0 氰美马嗪


CAS Name: 10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
Additional Names: 2-cyano-10-(3-dimethylamino-2-methylpropyl)phenothiazine; 10-(3-dimethylamino-2-methylpropyl)-3-cyanophenothiazine; cyamepromazineTrademarks: Kyamepromazine; Cianatil; Tercian (Thžaplix)
Percent Composition: C 70.55%, H 6.54%, N 12.99%, S 9.91%
📌 参考资料/链接:
Literature References: Prepn: Jacob, Robert, US 2877224 (1959 to Rhône-Poulenc). Synthesis: Craig et al., J. Org. Chem. 26, 1138 (1961). Biotransformation studies: Robinson, J. Pharm. Pharmacol. 18, 19 (1966). Chemistry: Kiger, Kiger, Ann. Pharm. Fr. 23, 489 (1965).

📄 详细内容


Properties: Yellow oil, bp0.2-0.5 205-220°; also reported as yellow powder, mp 89-96° (Kiger). Practically insol in water. Sol in ethanol and in organic solvents.
Melting point: mp 89-96° (Kiger)
Boiling point: bp0.2-0.5 205-220°
Derivative Type: Maleate
Percent Composition: C 62.85%, H 5.73%, N 9.56%, O 14.56%, S 7.30%
Properties: Pale yellow plates from methanol-ethanol, mp 196-197° (Craig).
Melting point: mp 196-197° (Craig)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.
产品链接: 3546-03-0››