Spizofurone CAS Registry Number: 72492-12-7 螺佐呋酮
CAS Name: 5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-oneTrademarks: Maon (Takeda)
Percent Composition: C 71.28%, H 4.98%, O 23.74%
📌 参考资料/链接：
Literature References: Prepn: H. Sugihara et al., EP 3084; eidem, US 4284644 (1979, 1981 both to Takeda); M. Kawada et al., Chem. Pharm. Bull. 32, 3532 (1984). One step synthesis: M. Watanabe et al., ibid. 3373. Anti-ulcerative effect in animals: N. Inatomi et al., Arzneim.-Forsch. 35, 1553 (1985). Cytoprotective effects on rat gastric mucosa: eidem, Eur. J. Pharmacol. 112, 81 (1985). Stimulation of endogenous prostaglandin synthesis in vitro: I. Inada et al., ibid. 124, 149 (1986).
📄 详细内容
Properties: Crystals from ethanol, mp 102-104° (Kawada); also reported as mp 106-107° (Watanabe).
Melting point: mp 102-104° (Kawada); mp 106-107° (Watanabe)
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Cytoprotectant (Gastric).
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 72492-12-7››